Instructive role of MLL-fusion proteins revealed by a model of t (4; 11) pro-B acute lymphoblastic leukemia S Lin, RT Luo, A Ptasinska, J Kerry, SA Assi, M Wunderlich, T Imamura, ... Cancer Cell 30 (5), 737-749, 2016 | 110 | 2016 |
The AS‐RBM15 lncRNA enhances RBM15 protein translation during megakaryocyte differentiation NT Tran, H Su, A Khodadadi‐Jamayran, S Lin, L Zhang, D Zhou, ... EMBO reports 17 (6), 887-900, 2016 | 74 | 2016 |
UBASH3B/Sts-1-CBL axis regulates myeloid proliferation in human preleukemia induced by AML1-ETO S Goyama, J Schibler, A Gasilina, M Shrestha, S Lin, KA Link, J Chen, ... Leukemia 30 (3), 728-739, 2016 | 62 | 2016 |
TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma BKA Seong, NV Dharia, S Lin, KA Donovan, S Chong, A Robichaud, ... Cancer cell 39 (9), 1262-1278. e7, 2021 | 60 | 2021 |
The thrombopoietin/MPL/Bcl-xL pathway is essential for survival and self-renewal in human preleukemia induced by AML1-ETO FS Chou, A Griesinger, M Wunderlich, S Lin, KA Link, M Shrestha, ... Blood 120 (4), 709-719, 2012 | 60 | 2012 |
RUNX1-ETO Leukemia S Lin, JC Mulloy, S Goyama RUNX Proteins in Development and Cancer, 151-173, 2017 | 58 | 2017 |
STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma B Adane, G Alexe, BKA Seong, D Lu, EE Hwang, D Hnisz, CA Lareau, ... Cancer Cell 39 (6), 827-844. e10, 2021 | 53 | 2021 |
Salt-inducible kinase inhibition suppresses acute myeloid leukemia progression in vivo Y Tarumoto, S Lin, J Wang, JP Milazzo, Y Xu, B Lu, Z Yang, Y Wei, ... Blood 135 (1), 56-70, 2020 | 49 | 2020 |
An in vivo CRISPR screening platform for prioritizing therapeutic targets in AML S Lin, C Larrue, NK Scheidegger, BKA Seong, NV Dharia, M Kuljanin, ... Cancer Discovery, 2021 | 43 | 2021 |
A FOXO1-induced oncogenic network defines the AML1-ETO preleukemic program S Lin, A Ptasinska, X Chen, M Shrestha, SA Assi, PS Chin, MR Imperato, ... Blood 130 (10), 1213-1222, 2017 | 42 | 2017 |
The full transforming capacity of MLL-Af4 is interlinked with lymphoid lineage commitment S Lin, RT Luo, M Shrestha, MJ Thirman, JC Mulloy Blood 130 (7), 903-907, 2017 | 37 | 2017 |
Epigenetic regulator genes direct lineage switching in MLL/AF4 leukemia R Tirtakusuma, K Szoltysek, P Milne, VV Grinev, A Ptasinska, PS Chin, ... Blood, The Journal of the American Society of Hematology 140 (17), 1875-1890, 2022 | 35 | 2022 |
Matched targeted therapy for pediatric patients with relapsed, refractory, or high-risk leukemias: A report from the LEAP consortium Y Pikman, SK Tasian, ML Sulis, K Stevenson, TM Blonquist, BA Winger, ... Cancer discovery 11 (6), 1424-1439, 2021 | 26 | 2021 |
Supraphysiologic levels of the AML1-ETO isoform AE9a are essential for transformation KA Link, S Lin, M Shrestha, M Bowman, M Wunderlich, CD Bloomfield, ... Proceedings of the National Academy of Sciences 113 (32), 9075-9080, 2016 | 24 | 2016 |
Unleashing cell-intrinsic inflammation as a strategy to kill AML blasts JM Ellegast, G Alexe, A Hamze, S Lin, HJ Uckelmann, PJ Rauch, ... Cancer Discovery 12 (7), 1760-1781, 2022 | 20 | 2022 |
Depletion of creatine phosphagen energetics with a covalent creatine kinase inhibitor N Darabedian, W Ji, M Fan, S Lin, HS Seo, EV Vinogradova, TM Yaron, ... Nature Chemical Biology, 1-10, 2023 | 18 | 2023 |
The ETS transcription factor ETV6 constrains the transcriptional activity of EWS–FLI to promote Ewing sarcoma DY Lu, JM Ellegast, KN Ross, CF Malone, S Lin, NW Mabe, NV Dharia, ... Nature Cell Biology, 1-13, 2023 | 17 | 2023 |
Immortalization of human AE pre-leukemia cells by hTERT allows leukemic transformation S Lin, J Wei, M Wunderlich, FS Chou, JC Mulloy Oncotarget 7 (35), 55939-55950, 2016 | 12 | 2016 |
Mitochondrial fusion is a therapeutic vulnerability of acute myeloid leukemia C Larrue, S Mouche, S Lin, F Simonetta, NK Scheidegger, L Poulain, ... Leukemia 37 (4), 765-775, 2023 | 10 | 2023 |
The Transcriptome Heterogeneity of MLL-Fusion ALL Is Driven By Fusion Partners Via Distinct Chromatin Binding S Lin, A Ptasinska, SA Assi, J Kerry, RA Meetei, RT Luo, MJ Thirman, ... Blood 128 (22), 576-576, 2016 | 3 | 2016 |