Selective inhibition of cocaine-seeking behaviour by a partial dopamine D3 receptor agonist M Pilla, S Perachon, F Sautel, F Garrido, A Mann, CG Wermuth, ... Nature 400 (6742), 371-375, 1999 | 707 | 1999 |
Identification of a low–molecular weight TrkB antagonist with anxiolytic and antidepressant activity in mice M Cazorla, J Prémont, A Mann, N Girard, C Kellendonk, D Rognan The Journal of clinical investigation 121 (5), 1846-1857, 2011 | 418 | 2011 |
Nafadotride, a potent preferential dopamine D3 receptor antagonist, activates locomotion in rodents. F Sautel, N Griffon, P Sokoloff, JC Schwartz, C Launay, P Simon, ... Journal of Pharmacology and Experimental Therapeutics 275 (3), 1239-1246, 1995 | 228 | 1995 |
N-(ω-(4-(2-methoxyphenyl) piperazin-1-yl) alkyl) carboxamides as dopamine D2 and D3 receptor ligands A Hackling, R Ghosh, S Perachon, A Mann, HD Höltje, CG Wermuth, ... Journal of medicinal chemistry 46 (18), 3883-3899, 2003 | 137 | 2003 |
Mild chemo-selective hydration of terminal alkynes catalysed by AgSbF 6 A Mann, A Wagner Chemical Communications 48 (3), 434-436, 2012 | 132 | 2012 |
A potent new beta2-adrenoceptor blocking agent. JL Imbs, F Miesch, J Schwartz, J Velly, G Leclerc, A Mann, CG Wermuth British Journal of Pharmacology 60 (3), 357, 1977 | 111 | 1977 |
Inhibition of cyclic adenosine-3', 5'-monophosphate phosphodiesterase from vascular smooth muscle by rolipram analogs MC Marivet, JJ Bourguignon, C Lugnier, A Mann, JC Stoclet, CG Wermuth Journal of medicinal chemistry 32 (7), 1450-1457, 1989 | 103 | 1989 |
Acylthiourea, acylurea, and acylguanidine derivatives with potent hedgehog inhibiting activity A Solinas, H Faure, H Roudaut, E Traiffort, A Schoenfelder, A Mann, ... Journal of medicinal chemistry 55 (4), 1559-1571, 2012 | 101 | 2012 |
Selective removal of the tert-butoxycarbonyl group from secondary amines: ZnBr2 as the deprotecting reagent SC Nigama, AÉ Mann, M Taddei, CG Wermutha Synthetic Communications 19 (18), 3139-3142, 1989 | 95 | 1989 |
Phenylaziridine as a masked 1, 3 dipole in reactions with nonactivated alkenes I Ungureanu, P Klotz, A Mann Angewandte Chemie International Edition 39 (24), 4615-4617, 2000 | 88 | 2000 |
Short access to (+)-lupinine and (+)-epiquinamide via double hydroformylation E Airiau, T Spangenberg, N Girard, B Breit, A Mann Organic Letters 12 (3), 528-531, 2010 | 82 | 2010 |
Synthesis and. beta.-adrenergic blocking activity of a novel class of aromatic oxime ethers G Leclerc, A Mann, CG Wermuth, N Bieth, J Schwartz Journal of medicinal chemistry 20 (12), 1657-1662, 1977 | 82 | 1977 |
Microwaves make hydroformylation a rapid and easy process E Petricci, A Mann, A Schoenfelder, A Rota, M Taddei Organic Letters 8 (17), 3725-3727, 2006 | 78 | 2006 |
Hydroformylation of alkenylamines. Concise approaches toward piperidines, quinolizidines, and related alkaloids E Airiau, N Girard, M Pizzeti, J Salvadori, M Taddei, A Mann The Journal of Organic Chemistry 75 (24), 8670-8673, 2010 | 76 | 2010 |
Conformational restriction and/or steric hindrance in medicinal chemistry A Mann The practice of medicinal chemistry, 363-379, 2008 | 75 | 2008 |
Hydroformylation of homoallylic azides: A rapid approach toward alkaloids T Spangenberg, B Breit, A Mann Organic Letters 11 (2), 261-264, 2009 | 74 | 2009 |
MRT-92 inhibits Hedgehog signaling by blocking overlapping binding sites in the transmembrane domain of the Smoothened receptor L Hoch, H Faure, H Roudaut, A Schoenfelder, A Mann, N Girard, ... The FASEB Journal 29 (5), 1817, 2015 | 70 | 2015 |
Stereoselective synthesis of 3-alkylated glutamic acids: application to the synthesis of secokainic acid I Jako, P Uiber, A Mann, CG Wermuth, T Boulanger, B Norberg, G Evrard, ... The Journal of Organic Chemistry 56 (19), 5729-5733, 1991 | 69 | 1991 |
1, 3-stereocontrol with bromoallenes. Synthesis of N-Boc-ADDA, the unique amino acid present in several inhibitors of serine/threonine phosphatases F DAniello, A Mann, M Taddei Journal of organic chemistry 61, 4870-4871, 1996 | 68 | 1996 |
Synthesis and biochemical evaluation of baclofen analogs locked in the baclofen solid-state conformation A Mann, T Boulanger, B Brandau, F Durant, G Evrard, M Heaulme, ... Journal of medicinal chemistry 34 (4), 1307-1313, 1991 | 68 | 1991 |