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Mahesh Tambe
Mahesh Tambe
Postdoctoral Researcher
在 helsinki.fi 的电子邮件经过验证
标题
引用次数
引用次数
年份
Novel Mad2-targeting miR-493-3p controls mitotic fidelity and cancer cells’ sensitivity to paclitaxel
M Tambe, S Pruikkonen, J Mäki-Jouppila, P Chen, BV Elgaaen, ...
Oncotarget 7 (11), 12267, 2016
442016
Excess of miRNA-378a-5p perturbs mitotic fidelity and correlates with breast cancer tumourigenesis in vivo
S Winsel, J Mäki-Jouppila, M Tambe, MR Aure, S Pruikkonen, AL Salmela, ...
British journal of cancer 111 (11), 2142-2151, 2014
332014
MicroRNA let-7b regulates genomic balance by targeting Aurora B kinase
JHE Mäki-Jouppila, S Pruikkonen, MB Tambe, MR Aure, T Halonen, ...
Molecular oncology 9 (6), 1056-1070, 2015
262015
Pan-RAF inhibition induces apoptosis in acute myeloid leukemia cells and synergizes with BCL2 inhibition
M Tambe, E Karjalainen, M Vähä-Koskela, D Bulanova, BT Gjertsen, ...
Leukemia 34 (12), 3186-3196, 2020
242020
Reduced levels of Dusp3/Vhr phosphatase impair normal spindle bipolarity in an Erk1/2 activity‐dependent manner
MB Tambe, E Narvi, M Kallio
FEBS letters 590 (16), 2757-2767, 2016
142016
Paradox-breaker Pan-RAF inhibitors induce an AML-specific cytotoxic response and synergize with venetoclax to display superior antileukemic activity
M Tambe, E Karjalainen, M Vaha-Koskela, CA Heckman, K Porkka, ...
Blood 132, 2210, 2018
32018
Venetoclax triggers sublethal apoptotic signaling in venetoclax-resistant acute myeloid leukemia cells and induces vulnerability to PARP inhibition and azacitidine
M Tambe, S Unterberger, MC Kriegbaum, I Vänttinen, EJ Olgac, ...
Cell Death & Disease 15 (10), 750, 2024
12024
Venetoclax triggers sub-lethal apoptotic signaling in venetoclax-resistant acute myeloid leukemia cells and induces vulnerability to PARP inhibition and azacitidine
C Heckman, M Tambe, M Kriegbaum, I Vänttinen, EJ Olgac, M Kontro, ...
12023
Efficacy of the Peptide Drug Conjugates Melflufen and OPDC3 in Venetoclax Resistant Acute Myeloid Leukemia
R Kumari, JJ Miettinen, MB Tambe, J Olgac, T Ruokoranta, N Ikonen, ...
Blood 144, 1548, 2024
2024
Predictors of Response and Rational Combinations for the Novel MCL-1 Inhibitor MIK665 in Acute Myeloid Leukemia
J Saad, R Newman, E Khabusheva, S Aakko, E Durand, MB Tambe, ...
Blood 144, 1560, 2024
2024
P426: HDAC INHIBITORS RESTORE SENSITIVITY TO VENETOCLAX AND NAVITOCLAX IN AML CELLS RESULTING IN THE IRREVERSIBLE DNA DAMAGE
E Khabusheva, M Tambe, J Miettinen, C Heckman
HemaSphere 7 (Suppl), e0089664, 2023
2023
New Roads to Genomic Imbalance: Microrna-and Protein Phosphatase-Mediated Regulation of Mitosis
M Tambe
Annales Universitatis Turkuensis D 1243, 2016
2016
Tumor suppressor miRNA let-7b promotes mitotic errors and targets Aurora B kinase
JH Maeki-Jouppila, S Pruikkonen, M Tambe, MR Aure, T Halonen, ...
FEBS JOURNAL 281, 84-85, 2014
2014
Sensitization of cancer cells to inhibitors of heat shock protein 90 (Hsp90) and proteasome by Abamectin
MB Tambe
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