Novel Mad2-targeting miR-493-3p controls mitotic fidelity and cancer cells’ sensitivity to paclitaxel M Tambe, S Pruikkonen, J Mäki-Jouppila, P Chen, BV Elgaaen, ... Oncotarget 7 (11), 12267, 2016 | 44 | 2016 |
Excess of miRNA-378a-5p perturbs mitotic fidelity and correlates with breast cancer tumourigenesis in vivo S Winsel, J Mäki-Jouppila, M Tambe, MR Aure, S Pruikkonen, AL Salmela, ... British journal of cancer 111 (11), 2142-2151, 2014 | 33 | 2014 |
MicroRNA let-7b regulates genomic balance by targeting Aurora B kinase JHE Mäki-Jouppila, S Pruikkonen, MB Tambe, MR Aure, T Halonen, ... Molecular oncology 9 (6), 1056-1070, 2015 | 26 | 2015 |
Pan-RAF inhibition induces apoptosis in acute myeloid leukemia cells and synergizes with BCL2 inhibition M Tambe, E Karjalainen, M Vähä-Koskela, D Bulanova, BT Gjertsen, ... Leukemia 34 (12), 3186-3196, 2020 | 24 | 2020 |
Reduced levels of Dusp3/Vhr phosphatase impair normal spindle bipolarity in an Erk1/2 activity‐dependent manner MB Tambe, E Narvi, M Kallio FEBS letters 590 (16), 2757-2767, 2016 | 14 | 2016 |
Paradox-breaker Pan-RAF inhibitors induce an AML-specific cytotoxic response and synergize with venetoclax to display superior antileukemic activity M Tambe, E Karjalainen, M Vaha-Koskela, CA Heckman, K Porkka, ... Blood 132, 2210, 2018 | 3 | 2018 |
Venetoclax triggers sublethal apoptotic signaling in venetoclax-resistant acute myeloid leukemia cells and induces vulnerability to PARP inhibition and azacitidine M Tambe, S Unterberger, MC Kriegbaum, I Vänttinen, EJ Olgac, ... Cell Death & Disease 15 (10), 750, 2024 | 1 | 2024 |
Venetoclax triggers sub-lethal apoptotic signaling in venetoclax-resistant acute myeloid leukemia cells and induces vulnerability to PARP inhibition and azacitidine C Heckman, M Tambe, M Kriegbaum, I Vänttinen, EJ Olgac, M Kontro, ... | 1 | 2023 |
Efficacy of the Peptide Drug Conjugates Melflufen and OPDC3 in Venetoclax Resistant Acute Myeloid Leukemia R Kumari, JJ Miettinen, MB Tambe, J Olgac, T Ruokoranta, N Ikonen, ... Blood 144, 1548, 2024 | | 2024 |
Predictors of Response and Rational Combinations for the Novel MCL-1 Inhibitor MIK665 in Acute Myeloid Leukemia J Saad, R Newman, E Khabusheva, S Aakko, E Durand, MB Tambe, ... Blood 144, 1560, 2024 | | 2024 |
P426: HDAC INHIBITORS RESTORE SENSITIVITY TO VENETOCLAX AND NAVITOCLAX IN AML CELLS RESULTING IN THE IRREVERSIBLE DNA DAMAGE E Khabusheva, M Tambe, J Miettinen, C Heckman HemaSphere 7 (Suppl), e0089664, 2023 | | 2023 |
New Roads to Genomic Imbalance: Microrna-and Protein Phosphatase-Mediated Regulation of Mitosis M Tambe Annales Universitatis Turkuensis D 1243, 2016 | | 2016 |
Tumor suppressor miRNA let-7b promotes mitotic errors and targets Aurora B kinase JH Maeki-Jouppila, S Pruikkonen, M Tambe, MR Aure, T Halonen, ... FEBS JOURNAL 281, 84-85, 2014 | | 2014 |
Sensitization of cancer cells to inhibitors of heat shock protein 90 (Hsp90) and proteasome by Abamectin MB Tambe | | |