Studies on the synthesis and opioid agonistic activities of mitragynine-related indole alkaloids: discovery of opioid agonists structurally different from other opioid ligands H Takayama, H Ishikawa, M Kurihara, M Kitajima, N Aimi, D Ponglux, ... Journal of medicinal chemistry 45 (9), 1949-1956, 2002 | 296 | 2002 |
Antinociceptive effect of 7-hydroxymitragynine in mice: Discovery of an orally active opioid analgesic from the Thai medicinal herb Mitragyna speciosa K Matsumoto, S Horie, H Ishikawa, H Takayama, N Aimi, D Ponglux, ... Life sciences 74 (17), 2143-2155, 2004 | 275 | 2004 |
Inhibition of Th17 differentiation by anti-TNF-alpha therapy in uveitis patients with Behcet’s disease S Sugita, Y Kawazoe, A Imai, Y Yamada, S Horie, M Mochizuki Arthritis research & therapy 14, 1-12, 2012 | 150 | 2012 |
Immunohistochemical co-localization of transient receptor potential vanilloid (TRPV) 1 and sensory neuropeptides in the guinea-pig respiratory system N Watanabe, S Horie, GJ Michael, S Keir, D Spina, CP Page, JV Priestley Neuroscience 141 (3), 1533-1543, 2006 | 148 | 2006 |
Inhibitory effect of mitragynine, an alkaloid with analgesic effect from Thai medicinal plant Mitragyna speciosa, on electrically stimulated contraction of isolated guinea-pig … K Watanabe, S Yano, S Horie, LT Yamamoto Life sciences 60 (12), 933-942, 1997 | 148 | 1997 |
Phenolic compounds from Gastrodia rhizome and relaxant effects of related compounds on isolated smooth muscle preparation J Hayashi, T Sekine, S Deguchi, Q Lin, S Horie, S Tsuchiya, S Yano, ... Phytochemistry 59 (5), 513-519, 2002 | 147 | 2002 |
Antinociception, tolerance and withdrawal symptoms induced by 7-hydroxymitragynine, an alkaloid from the Thai medicinal herb Mitragyna speciosa K Matsumoto, S Horie, H Takayama, H Ishikawa, N Aimi, D Ponglux, ... Life sciences 78 (1), 2-7, 2005 | 138 | 2005 |
Immune privilege and eye‐derived T‐regulatory cells H Keino, S Horie, S Sugita Journal of immunology research 2018 (1), 1679197, 2018 | 137 | 2018 |
Antinociceptive components of Ganoderma lucidum K Koyama, T Imaizumi, M Akiba, K Kinoshita, K Takahashi, A Suzuki, ... Planta Medica 63 (03), 224-227, 1997 | 135 | 1997 |
Opioid receptor agonistic characteristics of mitragynine pseudoindoxyl in comparison with mitragynine derived from Thai medicinal plant Mitragyna speciosa LT Yamamoto, S Horie, H Takayama, N Aimi, S Sakai, S Yano, J Shan, ... General Pharmacology: The Vascular System 33 (1), 73-81, 1999 | 127 | 1999 |
Chemical and Pharmaceutical Studies on Medicinal Plants in Paraguay, Geraniin, an Angiotensin-Converting Enzyme Inhibitor from" Paraparai Mi," Phyllanthus niruri H Ueno, S Horie, Y Nishi, H Shogawa, M Kawasaki, S Suzuki, T Hayashi, ... Journal of natural products 51 (2), 357-359, 1988 | 127 | 1988 |
Retinal pigment epithelium-derived CTLA-2α induces TGFβ-producing T regulatory cells S Sugita, S Horie, O Nakamura, Y Futagami, H Takase, H Keino, ... The Journal of Immunology 181 (11), 7525-7536, 2008 | 126 | 2008 |
Contractile effect of TRPA1 receptor agonists in the isolated mouse intestine A Penuelas, K Tashima, S Tsuchiya, K Matsumoto, T Nakamura, S Horie, ... European journal of pharmacology 576 (1-3), 143-150, 2007 | 125 | 2007 |
Involvement of μ-opioid receptors in antinociception and inhibition of gastrointestinal transit induced by 7-hydroxymitragynine, isolated from Thai herbal medicine Mitragyna … K Matsumoto, Y Hatori, T Murayama, K Tashima, S Wongseripipatana, ... European journal of pharmacology 549 (1-3), 63-70, 2006 | 125 | 2006 |
Immunohistochemical localization of vanilloid receptor subtype 1 (TRPV1) in the guinea pig respiratory system N Watanabe, S Horie, GJ Michael, D Spina, CP Page, JV Priestley Pulmonary pharmacology & therapeutics 18 (3), 187-197, 2005 | 119 | 2005 |
Inhibitory effect of mitragynine, an analgesic alkaloid from Thai herbal medicine, on neurogenic contraction of the vas deferens K Matsumoto, LT Yamamoto, K Watanabe, S Yano, J Shan, PKT Pang, ... Life sciences 78 (2), 187-194, 2005 | 112 | 2005 |
Suboptimal therapy controls clinically apparent disease but not subclinical progression of Vogt-Koyanagi-Harada disease T Kawaguchi, S Horie, N Bouchenaki, K Ohno-Matsui, M Mochizuki, ... International ophthalmology 30, 41-50, 2010 | 109 | 2010 |
Localization of TRPV1 and contractile effect of capsaicin in mouse large intestine: high abundance and sensitivity in rectum and distal colon K Matsumoto, E Kurosawa, H Terui, T Hosoya, K Tashima, T Murayama, ... American Journal of Physiology-Gastrointestinal and Liver Physiology, 2009 | 109 | 2009 |
Myeloid cells expressing VEGF and arginase-1 following uptake of damaged retinal pigment epithelium suggests potential mechanism that drives the onset of choroidal angiogenesis … J Liu, DA Copland, S Horie, WK Wu, M Chen, Y Xu, B Paul Morgan, ... PloS one 8 (8), e72935, 2013 | 104 | 2013 |
Protective role of vanilloid receptor type 1 in HCl‐induced gastric mucosal lesions in rats S Horie, H Yamamoto, GJ Michael, M Uchida, A Belai, K Watanabe, ... Scandinavian journal of gastroenterology 39 (4), 303-312, 2004 | 104 | 2004 |