Direct reprogramming of resident NG2 glia into neurons with properties of fast-spiking parvalbumin-containing interneurons M Pereira, M Birtele, S Shrigley, JA Benitez, E Hedlund, M Parmar, ... Stem cell reports 9 (3), 742-751, 2017 | 108 | 2017 |
Single cell transcriptomics identifies stem cell-derived graft composition in a model of Parkinson’s disease K Tiklová, S Nolbrant, A Fiorenzano, ÅK Björklund, Y Sharma, A Heuer, ... Nature communications 11 (1), 2434, 2020 | 93 | 2020 |
Single-cell transcriptomics captures features of human midbrain development and dopamine neuron diversity in brain organoids A Fiorenzano, E Sozzi, M Birtele, J Kajtez, J Giacomoni, F Nilsson, ... Nature communications 12 (1), 7302, 2021 | 61 | 2021 |
3D‐Printed soft lithography for complex compartmentalized microfluidic neural devices J Kajtez, S Buchmann, S Vasudevan, M Birtele, S Rocchetti, CJ Pless, ... Advanced Science 7 (16), 2001150, 2020 | 55 | 2020 |
Embedded 3D printing in self‐healing annealable composites for precise patterning of functionally mature human neural constructs J Kajtez, MF Wesseler, M Birtele, FR Khorasgani, D Rylander Ottosson, ... Advanced Science 9 (25), 2201392, 2022 | 34 | 2022 |
Direct reprogramming of human fetal-and stem cell-derived glial progenitor cells into midbrain dopaminergic neurons S Nolbrant, J Giacomoni, DB Hoban, A Bruzelius, M Birtele, ... Stem Cell Reports 15 (4), 869-882, 2020 | 24 | 2020 |
Age-related pathological impairments in directly reprogrammed dopaminergic neurons derived from patients with idiopathic Parkinson’s disease J Drouin-Ouellet, EM Legault, F Nilsson, K Pircs, J Bouquety, F Petit, ... Stem Cell Reports 17 (10), 2203-2219, 2022 | 23 | 2022 |
Dual modulation of neuron‐specific microRNAs and the REST complex promotes functional maturation of human adult induced neurons M Birtele, Y Sharma, S Kidnapillai, S Lau, TB Stoker, RA Barker, ... FEBS letters 593 (23), 3370-3380, 2019 | 20 | 2019 |
Direct reprogramming into interneurons: potential for brain repair M Pereira, M Birtele, D Rylander Ottosson Cellular and molecular life sciences 76, 3953-3967, 2019 | 19 | 2019 |
Silk scaffolding drives self-assembly of functional and mature human brain organoids E Sozzi, J Kajtez, A Bruzelius, MF Wesseler, F Nilsson, M Birtele, ... Frontiers in cell and developmental biology 10, 1023279, 2022 | 12 | 2022 |
Single-cell profiling of coding and noncoding genes in human dopamine neuron differentiation F Nilsson, P Storm, E Sozzi, D Hidalgo Gil, M Birtele, Y Sharma, M Parmar, ... Cells 10 (1), 137, 2021 | 12 | 2021 |
Non-synaptic function of the autism spectrum disorder-associated gene SYNGAP1 in cortical neurogenesis M Birtele, A Del Dosso, T Xu, T Nguyen, B Wilkinson, N Hosseini, ... Nature Neuroscience 26 (12), 2090-2103, 2023 | 10 | 2023 |
Human cerebellar organoids with functional Purkinje cells A Atamian, M Birtele, N Hosseini, T Nguyen, A Seth, A Del Dosso, S Paul, ... Cell Stem Cell 31 (1), 39-51. e6, 2024 | 9 | 2024 |
Single-cell transcriptional and functional analysis of dopaminergic neurons in organoid-like cultures derived from human fetal midbrain M Birtele, P Storm, Y Sharma, J Kajtez, JN Wahlestedt, E Sozzi, F Nilsson, ... Development 149 (23), dev200504, 2022 | 9 | 2022 |
Single cell gene expression analysis reveals human stem cell-derived graft composition in a cell therapy model of Parkinson’s disease K Tiklová, S Nolbrant, A Fiorenzano, ÅK Björklund, Y Sharma, A Heuer, ... bioRxiv, 720870, 2019 | 7 | 2019 |
In vivo direct reprogramming of resident glial cells into interneurons by intracerebral injection of viral vectors M Pereira, M Birtele, DR Ottosson JoVE (Journal of Visualized Experiments), e59465, 2019 | 7 | 2019 |
The autism-associated gene SYNGAP1 regulates human cortical neurogenesis M Birtele, AD Dosso, T Xu, T Nguyen, B Wilkinson, JP Urenda, G Knight, ... BioRxiv, 2022.05. 10.491244, 2022 | 6 | 2022 |
Evaluation of TH-Cre knock-in cell lines for detection and specific targeting of stem cell-derived dopaminergic neurons A Fiorenzano, M Birtele, JN Wahlestedt, M Parmar Heliyon 7 (1), 2021 | 6 | 2021 |
Present and future modeling of human psychiatric connectopathies with brain organoids JP Urenda, A Del Dosso, M Birtele, G Quadrato Biological Psychiatry 93 (7), 606-615, 2023 | 5 | 2023 |
Age-related pathological impairments in induced neurons derived from patients with idiopathic Parkinson’s disease J Drouin-Ouellet, K Pircs, EM Legault, M Birtele, F Nilsson, S Shrigley, ... Biorxiv, 2021.04. 23.441070, 2021 | 4 | 2021 |