The ageing haematopoietic stem cell compartment H Geiger, G De Haan, MC Florian Nature Reviews Immunology 13 (5), 376-389, 2013 | 601 | 2013 |
Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation MC Florian, K Dörr, A Niebel, D Daria, H Schrezenmeier, M Rojewski, ... Cell stem cell 10 (5), 520-530, 2012 | 525 | 2012 |
Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy. Cell 69 (5), 807-823, 2017 | 426 | 2017 |
A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing MC Florian, KJ Nattamai, K Dörr, G Marka, B Überle, V Vas, C Eckl, ... Nature 503 (7476), 392-396, 2013 | 322 | 2013 |
MiR-128 up-regulation inhibits Reelin and DCX expression and reduces neuroblastoma cell motility and invasiveness C Evangelisti, M Florian, I Massimi, C Dominici, G Giannini, S Galardi, ... The FASEB Journal 23 (12), 4276-4287, 2009 | 174 | 2009 |
Osteopontin attenuates aging‐associated phenotypes of hematopoietic stem cells N Guidi, M Sacma, L Ständker, K Soller, G Marka, K Eiwen, JM Weiss, ... The EMBO journal 36 (7), 840-853, 2017 | 153 | 2017 |
Understanding intrinsic hematopoietic stem cell aging E Mejia-Ramirez, MC Florian haematologica 105 (1), 22, 2020 | 127 | 2020 |
Aging alters the epigenetic asymmetry of HSC division MC Florian, M Klose, M Sacma, J Jablanovic, L Knudson, KJ Nattamai, ... PLoS biology 16 (9), e2003389, 2018 | 118 | 2018 |
Haematopoietic stem cells in perisinusoidal niches are protected from ageing M Saçma, J Pospiech, R Bogeska, W de Back, JP Mallm, V Sakk, K Soller, ... Nature cell biology 21 (11), 1309-1320, 2019 | 113 | 2019 |
Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging R Bogeska, AM Mikecin, P Kaschutnig, M Fawaz, M Büchler-Schäff, D Le, ... Cell stem cell 29 (8), 1273-1284. e8, 2022 | 103 | 2022 |
HSC aging and senescent immune remodeling MD Denkinger, H Leins, R Schirmbeck, MC Florian, H Geiger Trends in immunology 36 (12), 815-824, 2015 | 103 | 2015 |
Concise review: polarity in stem cells, disease, and aging M Carolina Florian, H Geiger Stem cells 28 (9), 1623-1629, 2010 | 101 | 2010 |
LaminA/C regulates epigenetic and chromatin architecture changes upon aging of hematopoietic stem cells A Grigoryan, N Guidi, K Senger, T Liehr, K Soller, G Marka, A Vollmer, ... Genome biology 19, 1-21, 2018 | 77 | 2018 |
Retinoic acid reduces human neuroblastoma cell migration and invasiveness: effects on DCX, LIS1, neurofilaments-68 and vimentin expression E Messi, MC Florian, C Caccia, M Zanisi, R Maggi BMC cancer 8, 1-12, 2008 | 64 | 2008 |
Acute myeloid leukemia: aging and epigenetics P Zjablovskaja, MC Florian Cancers 12 (1), 103, 2019 | 61 | 2019 |
Stem cell-specific mechanisms ensure genomic fidelity within HSCs and upon aging of HSCs BM Moehrle, K Nattamai, A Brown, MC Florian, M Ryan, M Vogel, ... Cell reports 13 (11), 2412-2424, 2015 | 61 | 2015 |
Atypical protein kinase C (aPKCζ and aPKCλ) is dispensable for mammalian hematopoietic stem cell activity and blood formation A Sengupta, A Duran, E Ishikawa, MC Florian, SK Dunn, AM Ficker, ... Proceedings of the National Academy of Sciences 108 (24), 9957-9962, 2011 | 59 | 2011 |
Rational identification of a Cdc42 inhibitor presents a new regimen for long-term hematopoietic stem cell mobilization W Liu, W Du, X Shang, L Wang, C Evelyn, MC Florian, M A. Ryan, ... Leukemia 33 (3), 749-761, 2019 | 50 | 2019 |
Niche WNT5A regulates the actin cytoskeleton during regeneration of hematopoietic stem cells C Schreck, R Istvánffy, C Ziegenhain, T Sippenauer, F Ruf, L Henkel, ... Journal of experimental medicine 214 (1), 165-181, 2017 | 48 | 2017 |
RhoA GTPase controls cytokinesis and programmed necrosis of hematopoietic progenitors X Zhou, MC Florian, P Arumugam, X Chen, JA Cancelas, R Lang, P Malik, ... Journal of Experimental Medicine 210 (11), 2371-2385, 2013 | 45 | 2013 |