The landscape of cancer genes and mutational processes in breast cancer PJ Stephens, PS Tarpey, H Davies, P Van Loo, C Greenman, DC Wedge, ... Nature 486 (7403), 400-404, 2012 | 1945 | 2012 |
NASH limits anti-tumour surveillance in immunotherapy-treated HCC D Pfister, NG Núñez, R Pinyol, O Govaere, M Pinter, M Szydlowska, ... Nature 592 (7854), 450-456, 2021 | 923 | 2021 |
Clinical relevance of the Helicobacter pylori gene for blood-group antigen-binding adhesin M Gerhard, N Lehn, N Neumayer, T Borén, R Rad, W Schepp, S Miehlke, ... Proceedings of the National Academy of Sciences 96 (22), 12778-12783, 1999 | 856 | 1999 |
Generation of transgene-free induced pluripotent mouse stem cells by the piggyBac transposon K Yusa, R Rad, J Takeda, A Bradley Nature methods 6 (5), 363-369, 2009 | 801 | 2009 |
Direct identification of clinically relevant neoepitopes presented on native human melanoma tissue by mass spectrometry M Bassani-Sternberg, E Bräunlein, R Klar, T Engleitner, P Sinitcyn, ... Nature communications 7 (1), 13404, 2016 | 680 | 2016 |
Targeted Restoration of the Intestinal Microbiota with a Simple, Defined Bacteriotherapy Resolves Relapsing Clostridium difficile Disease in Mice TD Lawley, S Clare, AW Walker, MD Stares, TR Connor, C Raisen, ... PLoS pathogens 8 (10), e1002995, 2012 | 671 | 2012 |
Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV A Stukalov, V Girault, V Grass, O Karayel, V Bergant, C Urban, DA Haas, ... Nature 594 (7862), 246-252, 2021 | 664 | 2021 |
Leukemia-associated somatic mutations drive distinct patterns of age-related clonal hemopoiesis T McKerrell, N Park, T Moreno, CS Grove, H Ponstingl, J Stephens, ... Cell reports 10 (8), 1239-1245, 2015 | 552 | 2015 |
Cytokine gene polymorphisms influence mucosal cytokine expression, gastric inflammation, and host specific colonisation during Helicobacter pylori infection R Rad, A Dossumbekova, B Neu, R Lang, S Bauer, D Saur, M Gerhard, ... Gut 53 (8), 1082-1089, 2004 | 461 | 2004 |
Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer S Eser, N Reiff, M Messer, B Seidler, K Gottschalk, M Dobler, M Hieber, ... Cancer cell 23 (3), 406-420, 2013 | 411 | 2013 |
Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes S Mueller, T Engleitner, R Maresch, M Zukowska, S Lange, ... Nature 554 (7690), 62-68, 2018 | 404 | 2018 |
Toll-like receptor expression in human keratinocytes: nuclear factor κB controlled gene activation by Staphylococcus aureus is Toll-like receptor 2 but not Toll-like receptor 4 … M Mempel, V Voelcker, G Köllisch, C Plank, R Rad, M Gerhard, ... Journal of Investigative Dermatology 121 (6), 1389-1396, 2003 | 358 | 2003 |
CD25+/Foxp3+ T cells regulate gastric inflammation and Helicobacter pylori colonization in vivo R Rad, L Brenner, S Bauer, S Schwendy, L Layland, CP da Costa, ... Gastroenterology 131 (2), 525-537, 2006 | 353 | 2006 |
Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH M Dudek, D Pfister, S Donakonda, P Filpe, A Schneider, M Laschinger, ... Nature 592 (7854), 444-449, 2021 | 346 | 2021 |
Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer M Malehmir, D Pfister, S Gallage, M Szydlowska, D Inverso, E Kotsiliti, ... Nature medicine 25 (4), 641-655, 2019 | 346 | 2019 |
Rapid and efficient reprogramming of somatic cells to induced pluripotent stem cells by retinoic acid receptor gamma and liver receptor homolog 1 W Wang, J Yang, H Liu, D Lu, X Chen, Z Zenonos, LS Campos, R Rad, ... Proceedings of the National Academy of Sciences 108 (45), 18283-18288, 2011 | 298 | 2011 |
Tissue-specific tumorigenesis: context matters G Schneider, M Schmidt-Supprian, R Rad, D Saur Nature Reviews Cancer 17 (4), 239-253, 2017 | 296 | 2017 |
PiggyBac transposon mutagenesis: a tool for cancer gene discovery in mice R Rad, L Rad, W Wang, J Cadinanos, G Vassiliou, S Rice, LS Campos, ... Science 330 (6007), 1104-1107, 2010 | 293 | 2010 |
Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice GS Vassiliou, JL Cooper, R Rad, J Li, S Rice, A Uren, L Rad, P Ellis, ... Nature genetics 43 (5), 470-475, 2011 | 272 | 2011 |
The Helicobacter pylori blood group antigen-binding adhesin facilitates bacterial colonization and augments a nonspecific immune response R Rad, M Gerhard, R Lang, M Schöniger, T Rösch, W Schepp, ... The Journal of Immunology 168 (6), 3033-3041, 2002 | 266 | 2002 |