Counting absolute numbers of molecules using unique molecular identifiers T Kivioja, A Vähärautio, K Karlsson, M Bonke, M Enge, S Linnarsson, ... Nature methods 9 (1), 72-74, 2012 | 1228 | 2012 |
Organoid modeling of the tumor immune microenvironment JT Neal, X Li, J Zhu, V Giangarra, CL Grzeskowiak, J Ju, IH Liu, SH Chiou, ... Cell 175 (7), 1972-1988. e16, 2018 | 1116 | 2018 |
Applications of organoids for cancer biology and precision medicine YH Lo, K Karlsson, CJ Kuo Nature Cancer 1 (8), 761-773, 2020 | 117 | 2020 |
A CRISPR/Cas9-Engineered ARID1A-Deficient Human Gastric Cancer Organoid Model Reveals Essential and Nonessential Modes of Oncogenic Transformation YH Lo, KS Kolahi, Y Du, CY Chang, A Krokhotin, A Nair, WD Sobba, ... Cancer discovery 11 (6), 1562-1581, 2021 | 104 | 2021 |
Counting absolute number of molecules using unique molecular identifiers T Kivioja, A Vähärautio, K Karlsson, M Bonke, S Linnarsson, J Taipale Nature Precedings, 1-1, 2011 | 79 | 2011 |
Single-cell mRNA isoform diversity in the mouse brain K Karlsson, S Linnarsson BMC genomics 18, 1-11, 2017 | 66 | 2017 |
Single cell transcriptomics suggest that human adipocyte progenitor cells constitute a homogeneous cell population JR Acosta, S Joost, K Karlsson, A Ehrlund, X Li, M Aouadi, M Kasper, ... Stem Cell Research & Therapy 8, 1-6, 2017 | 65 | 2017 |
Amplification-free sequencing of cell-free DNA for prenatal non-invasive diagnosis of chromosomal aberrations K Karlsson, E Sahlin, E Iwarsson, M Westgren, M Nordenskjöld, ... Genomics 105 (3), 150-158, 2015 | 39 | 2015 |
Cancer-specific changes in DNA methylation reveal aberrant silencing and activation of enhancers in leukemia Y Qu, L Siggens, L Cordeddu, VI Gaidzik, K Karlsson, L Bullinger, ... Blood, The Journal of the American Society of Hematology 129 (7), e13-e25, 2017 | 37 | 2017 |
Deterministic evolution and stringent selection during preneoplasia K Karlsson, MJ Przybilla, E Kotler, A Khan, H Xu, K Karagyozova, ... Nature 618 (7964), 383-393, 2023 | 30 | 2023 |
Alternative TSSs are co‐regulated in single cells in the mouse brain K Karlsson, P Lönnerberg, S Linnarsson Molecular systems biology 13 (5), 930, 2017 | 25 | 2017 |
Experimental evolution in TP53 deficient human gastric organoids recapitulates tumorigenesis K Karlsson, M Przybilla, H Xu, E Kotler, K Karagyozova, A Sockell, K Liu, ... BioRxiv, 2022.04. 09.487529, 2022 | 9 | 2022 |
A microwell platform for high-throughput longitudinal phenotyping and selective retrieval of organoids A Sockell, W Wong, S Longwell, T Vu, K Karlsson, D Mokhtari, J Schaepe, ... Cell systems 14 (9), 764-776. e6, 2023 | 3 | 2023 |
Counting Molecules in Cell-free DNA and Single Cells RNA K Karlsson PQDT-Global, 2016 | 1 | 2016 |
Engineered matrices reveal stiffness-mediated chemoresistance in patient-derived pancreatic cancer organoids BL LeSavage, D Zhang, C Huerta-López, AE Gilchrist, BA Krajina, ... Nature Materials, 1-12, 2024 | | 2024 |
Advancing radiotherapy strategies for high-risk rhabdomyosarcoma: Unveiling BCL-xL inhibition as a potent sensitizer to radiotherapy S Se Whee Park, N Struyf, T Erkers, S Lehmann, MT Meister, J Drost, ... Cancer Research 84 (6_Supplement), 706-706, 2024 | | 2024 |
Large scale drug response comparison across different neuroblastoma cell model systems SW Park, E Liu, A Los, B Seashore-Ludlow, P Östling, J Molenaar, ... Cancer Research 84 (6_Supplement), 4727-4727, 2024 | | 2024 |
NOVEL DRUG COMBINATIONS FOR NEUROBLASTOMA THERAPY-EXPLORING THE FULL POTENTIAL OF THE ROCK2-SPECIFIC INHIBITOR KD025 C Tummler, A Pepich, Q Vellema, S Abu Ajamieh, SW Park, L Ljungblad, ... PEDIATRIC BLOOD & CANCER 69, S230-S230, 2022 | | 2022 |
A new mutant NPM1/IDH2R140-and PML-RARA-associated lncRNA MALNC plays a role in AML biology, prognosis and drug response A Neddermeyer, M Björklund, K Dimitris, N Struyf, K Karlsson, Y Qu, ... | | 2022 |
Sa134 A CRISPR/CAS9-ENGINEERED ARID1A-DEFICIENT HUMAN GASTRIC CANCER ORGANOID MODEL REVEALS ESSENTIAL AND NON-ESSENTIAL MODES OF ONCOGENIC TRANSFORMATION YH Lo, K Kolahi, Y Du, CY Chang, A Krokhotin, A Nair, W Sobba, ... Gastroenterology 160 (6), S-432, 2021 | | 2021 |