Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study A Sáez-Cirión, C Bacchus, L Hocqueloux, V Avettand-Fenoel, I Girault, ... PLoS pathogens 9 (3), e1003211, 2013 | 1185 | 2013 |
HIV controllers exhibit potent CD8 T cell capacity to suppress HIV infection ex vivo and peculiar cytotoxic T lymphocyte activation phenotype A Sáez-Cirión, C Lacabaratz, O Lambotte, P Versmisse, A Urrutia, ... Proceedings of the National Academy of Sciences 104 (16), 6776-6781, 2007 | 755 | 2007 |
International AIDS Society global scientific strategy: towards an HIV cure 2016 SG Deeks, SR Lewin, AL Ross, J Ananworanich, M Benkirane, P Cannon, ... Nature medicine 22 (8), 839-850, 2016 | 490 | 2016 |
Antigen sensitivity is a major determinant of CD8+ T-cell polyfunctionality and HIV-suppressive activity JR Almeida, D Sauce, DA Price, L Papagno, SY Shin, A Moris, M Larsen, ... Blood, The Journal of the American Society of Hematology 113 (25), 6351-6360, 2009 | 283 | 2009 |
Heterogeneity in HIV suppression by CD8 T cells from HIV controllers: association with Gag-specific CD8 T cell responses A Sáez-Cirión, M Sinet, SY Shin, A Urrutia, P Versmisse, C Lacabaratz, ... The Journal of Immunology 182 (12), 7828-7837, 2009 | 261 | 2009 |
HIV-1 virological remission lasting more than 12 years after interruption of early antiretroviral therapy in a perinatally infected teenager enrolled in the French ANRS EPF … P Frange, A Faye, V Avettand-Fenoël, E Bellaton, D Descamps, M Angin, ... The lancet HIV 3 (1), e49-e54, 2016 | 181 | 2016 |
HIV cure research: advances and prospects CP Passaes, A Sáez-Cirión Virology 454, 340-352, 2014 | 172 | 2014 |
Cellular metabolism is a major determinant of HIV-1 reservoir seeding in CD4+ T cells and offers an opportunity to tackle infection JC Valle-Casuso, M Angin, S Volant, C Passaes, V Monceaux, ... Cell metabolism 29 (3), 611-626. e5, 2019 | 161 | 2019 |
Sphingomyelin and cholesterol promote HIV-1 gp41 pretransmembrane sequence surface aggregation and membrane restructuring A Sáez-Cirión, S Nir, M Lorizate, A Agirre, A Cruz, J Pérez-Gil, JL Nieva Journal of Biological Chemistry 277 (24), 21776-21785, 2002 | 155 | 2002 |
Restriction of HIV-1 replication in macrophages and CD4+ T cells from HIV controllers A Sáez-Cirión, C Hamimi, A Bergamaschi, A David, P Versmisse, ... Blood, The Journal of the American Society of Hematology 118 (4), 955-964, 2011 | 144 | 2011 |
HIV controllers: how do they tame the virus? A Sáez-Cirión, G Pancino, M Sinet, A Venet, O Lambotte Trends in immunology 28 (12), 532-540, 2007 | 137 | 2007 |
Clinical and public health implications of acute and early HIV detection and treatment: a scoping review SE Rutstein, J Ananworanich, S Fidler, C Johnson, EJ Sanders, O Sued, ... African Journal of Reproduction and Gynaecological Endoscopy 20 (1), 2017 | 135 | 2017 |
Replication-competent HIV strains infect HIV controllers despite undetectable viremia (ANRS EP36 study) A Lamine, A Caumont-Sarcos, ML Chaix, A Saez-Cirion, C Rouzioux, ... Aids 21 (8), 1043-1045, 2007 | 135 | 2007 |
Combined ART started during acute HIV infection protects central memory CD4+ T cells and can induce remission A Cheret, C Bacchus-Souffan, V Avettand-Fenoël, A Mélard, G Nembot, ... Journal of Antimicrobial Chemotherapy 70 (7), 2108-2120, 2015 | 119 | 2015 |
The pre-transmembrane region of the human immunodeficiency virus type-1 glycoprotein: a novel fusogenic sequence T Suárez, S Nir, FM Goñi, A Saéz-Cirión, JL Nieva FEBS letters 477 (1-2), 145-149, 2000 | 117 | 2000 |
p21-mediated RNR2 repression restricts HIV-1 replication in macrophages by inhibiting dNTP biosynthesis pathway A Allouch, A David, SM Amie, H Lahouassa, L Chartier, ... Proceedings of the National Academy of Sciences 110 (42), E3997-E4006, 2013 | 113 | 2013 |
Elevated IP10 levels are associated with immune activation and low CD4+ T-cell counts in HIV controller patients N Noel, F Boufassa, C Lécuroux, A Saez-Cirion, C Bourgeois, ... Aids 28 (4), 467-476, 2014 | 108 | 2014 |
High antibody-dependent cellular cytotoxicity responses are correlated with strong CD8 T cell viral suppressive activity but not with B57 status in HIV-1 elite controllers O Lambotte, J Pollara, F Boufassa, C Moog, A Venet, BF Haynes, ... PloS one 8 (9), e74855, 2013 | 103 | 2013 |
Structural and functional roles of HIV-1 gp41 pretransmembrane sequence segmentation A Sáez-Cirión, JLR Arrondo, MJ Gómara, M Lorizate, I Iloro, G Melikyan, ... Biophysical Journal 85 (6), 3769-3780, 2003 | 98 | 2003 |
In-depth virological and immunological characterization of HIV-1 cure after CCR5Δ32/Δ32 allogeneic hematopoietic stem cell transplantation BEO Jensen, E Knops, L Cords, N Lübke, M Salgado, K Busman-Sahay, ... Nature medicine 29 (3), 583-587, 2023 | 92 | 2023 |