| Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases M Steger, F Tonelli, G Ito, P Davies, M Trost, M Vetter, S Wachter, ... elife 5, e12813, 2016 | 910 | 2016 |
| Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ... Science 370 (6521), eabe9403, 2020 | 647 | 2020 |
| Characterization of a selective inhibitor of the Parkinson's disease kinase LRRK2 X Deng, N Dzamko, A Prescott, P Davies, Q Liu, Q Yang, JD Lee, ... Nature chemical biology 7 (4), 203-205, 2011 | 474 | 2011 |
| Characterization of VPS34-IN1, a selective inhibitor of Vps34, reveals that the phosphatidylinositol 3-phosphate-binding SGK3 protein kinase is a downstream target of class III … R Bago, N Malik, MJ Munson, AR Prescott, P Davies, E Sommer, N Shpiro, ... Biochemical Journal 463 (3), 413-427, 2014 | 305 | 2014 |
| Progressive dopaminergic alterations and mitochondrial abnormalities in LRRK2 G2019S knock-in mice M Yue, KM Hinkle, P Davies, E Trushina, FC Fiesel, TA Christenson, ... Neurobiology of disease 78, 172-195, 2015 | 260 | 2015 |
| Alpha-synuclein is a cellular ferrireductase P Davies, D Moualla, DR Brown PloS one 6 (1), e15814, 2011 | 233 | 2011 |
| A plasmid DNA-launched SARS-CoV-2 reverse genetics system and coronavirus toolkit for COVID-19 research SJ Rihn, A Merits, S Bakshi, ML Turnbull, A Wickenhagen, AJT Alexander, ... PLoS biology 19 (2), e3001091, 2021 | 190 | 2021 |
| LRRK2 is a negative regulator of Mycobacterium tuberculosis phagosome maturation in macrophages A Härtlova, S Herbst, J Peltier, A Rodgers, O Bilkei‐Gorzo, A Fearns, ... The EMBO journal 37 (12), e98694, 2018 | 174 | 2018 |
| Development of phospho-specific Rab protein antibodies to monitor in vivo activity of the LRRK2 Parkinson's disease kinase P Lis, S Burel, M Steger, M Mann, F Brown, F Diez, F Tonelli, JL Holton, ... Biochemical Journal 475 (1), 1-22, 2018 | 132 | 2018 |
| Deconvoluting the Cu2+ binding modes of full-length prion protein M Klewpatinond, P Davies, S Bowen, DR Brown, JH Viles Journal of Biological Chemistry 283 (4), 1870-1881, 2008 | 120 | 2008 |
| Manganese binding to the prion protein MW Brazier, P Davies, E Player, F Marken, JH Viles, DR Brown Journal of Biological Chemistry 283 (19), 12831-12839, 2008 | 115 | 2008 |
| Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies P Davies, KM Hinkle, NN Sukar, B Sepulveda, R Mesias, G Serrano, ... Biochemical Journal 453 (1), 101-113, 2013 | 101 | 2013 |
| The cellular prion protein traps Alzheimer's Aβ in an oligomeric form and disassembles amyloid fibers ND Younan, CJ Sarell, P Davies, DR Brown, JH Viles The FASEB Journal 27 (5), 1847, 2013 | 101 | 2013 |
| Early onset prion disease from octarepeat expansion correlates with copper binding properties DJ Stevens, ED Walter, A Rodríguez, D Draper, P Davies, DR Brown, ... PLoS pathogens 5 (4), e1000390, 2009 | 93 | 2009 |
| The synucleins are a family of redox-active copper binding proteins P Davies, X Wang, CJ Sarell, A Drewett, F Marken, JH Viles, DR Brown Biochemistry 50 (1), 37-47, 2011 | 85 | 2011 |
| The chemistry of copper binding to PrP: is there sufficient evidence to elucidate a role for copper in protein function? P Davies, DR Brown Biochemical Journal 410 (2), 237-244, 2008 | 83 | 2008 |
| Photoactivatable prodrugs of antimelanoma agent vemurafenib R Horbert, B Pinchuk, P Davies, D Alessi, C Peifer ACS chemical biology 10 (9), 2099-2107, 2015 | 77 | 2015 |
| Biochemical characterization of protease activity of Nsp3 from SARS-CoV-2 and its inhibition by nanobodies LA Armstrong, SM Lange, V Dee Cesare, SP Matthews, RS Nirujogi, ... PloS one 16 (7), e0253364, 2021 | 71 | 2021 |
| Investigation of LKB1 Ser431 phosphorylation and Cys433 farnesylation using mouse knockin analysis reveals an unexpected role of prenylation in regulating … VP Houde, MS Ritorto, R Gourlay, J Varghese, P Davies, N Shpiro, ... Biochemical Journal 458 (1), 41-56, 2014 | 71 | 2014 |
| Copper (II)-induced secondary structure changes and reduced folding stability of the prion protein ND Younan, M Klewpatinond, P Davies, AV Ruban, DR Brown, JH Viles Journal of molecular biology 410 (3), 369-382, 2011 | 71 | 2011 |
