Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ... Science 370 (6521), eabe9403, 2020 | 666 | 2020 |
Antiproliferative and cytotoxic effects of some σ2 agonists and σ1 antagonists in tumour cell lines NA Colabufo, F Berardi, M Contino, M Niso, C Abate, R Perrone, ... Naunyn-Schmiedeberg's archives of pharmacology 370, 106-113, 2004 | 146 | 2004 |
4-(Tetralin-1-yl)- and 4-(Naphthalen-1-yl)alkyl Derivatives of 1-Cyclohexylpiperazine as σ Receptor Ligands with Agonist σ2 Activity F Berardi, S Ferorelli, C Abate, NA Colabufo, M Contino, R Perrone, ... Journal of medicinal chemistry 47 (9), 2308-2317, 2004 | 108 | 2004 |
Elements in support of the ‘non-identity’of the PGRMC1 protein with the σ2 receptor C Abate, M Niso, V Infantino, A Menga, F Berardi European journal of pharmacology 758, 16-23, 2015 | 82 | 2015 |
Lysosomal membrane permeabilization is an early event in Sigma-2 receptor ligand mediated cell death in pancreatic cancer JR Hornick, S Vangveravong, D Spitzer, C Abate, F Berardi, ... Journal of Experimental & Clinical Cancer Research 31, 1-11, 2012 | 78 | 2012 |
Is the σ2 Receptor a Histone Binding Protein? NA Colabufo, F Berardi, C Abate, M Contino, M Niso, R Perrone Journal of medicinal chemistry 49 (14), 4153-4158, 2006 | 64 | 2006 |
Sigma‐2 Receptor Agonists as Possible Antitumor Agents in Resistant Tumors: Hints for Collateral Sensitivity M Niso, C Abate, M Contino, S Ferorelli, A Azzariti, R Perrone, ... ChemMedChem 8 (12), 2026-2035, 2013 | 60 | 2013 |
Analogues of σ receptor ligand 1-cyclohexyl-4-[3-(5-methoxy-1, 2, 3, 4-tetrahydronaphthalen-1-yl) propyl] piperazine (PB28) with added polar functionality and reduced … C Abate, M Niso, E Lacivita, PD Mosier, A Toscano, R Perrone Journal of medicinal chemistry 54 (4), 1022-1032, 2011 | 58 | 2011 |
Sigma-2 receptor: past, present and perspectives on multiple therapeutic exploitations C Abate, M Niso, F Berardi Future medicinal chemistry 10 (16), 1997-2018, 2018 | 57 | 2018 |
Novel 4-(4-Aryl)cyclohexyl-1-(2-pyridyl)piperazines as Δ8−Δ7 Sterol Isomerase (Emopamil Binding Protein) Selective Ligands with Antiproliferative Activity F Berardi, C Abate, S Ferorelli, AF de Robertis, M Leopoldo, NA Colabufo, ... Journal of medicinal chemistry 51 (23), 7523-7531, 2008 | 56 | 2008 |
Sigma-2 receptor and progesterone receptor membrane component 1 (PGRMC1) are two different proteins: Proofs by fluorescent labeling and binding of sigma-2 receptor ligands to … ML Pati, D Groza, C Riganti, J Kopecka, M Niso, F Berardi, S Hager, ... Pharmacological research 117, 67-74, 2017 | 54 | 2017 |
Exploring the Importance of Piperazine N-Atoms for σ2 Receptor Affinity and Activity in a Series of Analogs of 1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4 … F Berardi, C Abate, S Ferorelli, V Uricchio, NA Colabufo, M Niso, ... Journal of medicinal chemistry 52 (23), 7817-7828, 2009 | 53 | 2009 |
1‐Cyclohexyl‐4‐(4‐arylcyclohexyl)piperazines: Mixed σ and Human Δ8–Δ7 Sterol Isomerase Ligands with Antiproliferative and P‐Glycoprotein Inhibitory Activity C Abate, M Niso, M Contino, NA Colabufo, S Ferorelli, R Perrone, ... ChemMedChem 6 (1), 73-80, 2011 | 51 | 2011 |
PB183, a sigma receptor ligand, as a potential PET probe for the imaging of prostate adenocarcinoma NA Colabufo, C Abate, M Contino, C Inglese, M Niso, F Berardi, ... Bioorganic & medicinal chemistry letters 18 (6), 1990-1993, 2008 | 49 | 2008 |
Development of 3, 4-dihydroisoquinolin-1 (2H)-one derivatives for the positron emission tomography (PET) imaging of σ2 receptors C Abate, SV Selivanova, A Müller, SD Krämer, R Schibli, R Marottoli, ... European Journal of Medicinal Chemistry 69, 920-930, 2013 | 47 | 2013 |
Live imaging reveals a new role for the sigma-1 (σ1) receptor in allowing microglia to leave brain injuries C Moritz, F Berardi, C Abate, F Peri Neuroscience letters 591, 13-18, 2015 | 44 | 2015 |
Arylamides hybrids of two high-affinity σ2 receptor ligands as tools for the development of PET radiotracers C Abate, S Ferorelli, M Contino, R Marottoli, NA Colabufo, R Perrone, ... European journal of medicinal chemistry 46 (9), 4733-4741, 2011 | 44 | 2011 |
1-Cyclohexylpiperazine and 3, 3-Dimethylpiperidine derivatives as sigma-1 (sig1) and sigma-2 (sig2) receptor ligands: a review F Berardi, C Abate, S Ferorelli, NA Colabufo, R Perrone Central Nervous System Agents in Medicinal Chemistry (Formerly Current …, 2009 | 44 | 2009 |
Perspectives of Cannabinoid Type 2 Receptor (CB2R) Ligands in Neurodegenerative Disorders: Structure–Affinity Relationship (SAfiR) and Structure–Activity Relationship (SAR … F Spinelli, E Capparelli, C Abate, NA Colabufo, M Contino Journal of Medicinal Chemistry 60 (24), 9913-9931, 2017 | 43 | 2017 |
Sigma-2 receptor agonist derivatives of 1-Cyclohexyl-4-[3-(5-methoxy-1, 2, 3, 4-tetrahydronaphthalen-1-yl) propyl] piperazine (PB28) induce cell death via mitochondrial … ML Pati, JR Hornick, M Niso, F Berardi, D Spitzer, C Abate, W Hawkins BMC cancer 17, 1-12, 2017 | 42 | 2017 |