| Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy H Han, AD Jain, MI Truica, J Izquierdo-Ferrer, JF Anker, B Lysy, V Sagar, ... Cancer Cell 36 (5), 483-497, 2019 | 309 | 2019 |
| Probing the structural requirements of non-electrophilic naphthalene-based Nrf2 activators AD Jain, H Potteti, BG Richardson, L Kingsley, JP Luciano, AF Ryuzoji, ... European journal of medicinal chemistry 103, 252-268, 2015 | 98 | 2015 |
| Structural modification of the designer stimulant α-pyrrolidinovalerophenone (α-PVP) influences potency at dopamine transporters R Kolanos, F Sakloth, AD Jain, JS Partilla, MH Baumann, RA Glennon ACS chemical neuroscience 6 (10), 1726-1731, 2015 | 86 | 2015 |
| Non-electrophilic modulators of the canonical Keap1/Nrf2 pathway BG Richardson, AD Jain, TE Speltz, TW Moore Bioorganic & medicinal chemistry letters 25 (11), 2261-2268, 2015 | 77 | 2015 |
| Development of GLUT4-selective antagonists for multiple myeloma therapy C Wei, R Bajpai, H Sharma, M Heitmeier, AD Jain, SM Matulis, AK Nooka, ... European journal of medicinal chemistry 139, 573-586, 2017 | 51 | 2017 |
| Replacement of a naphthalene scaffold in Kelch-like ECH-associated protein 1 (KEAP1)/nuclear factor (erythroid-derived 2)-like 2 (NRF2) inhibitors BG Richardson, AD Jain, HR Potteti, PR Lazzara, BP David, CR Tamatam, ... Journal of medicinal chemistry 61 (17), 8029-8047, 2018 | 49 | 2018 |
| Deconstruction of the α4β2 nicotinic acetylcholine receptor positive allosteric modulator desformylflustrabromine N German, JS Kim, A Jain, M Dukat, A Pandya, Y Ma, M Weltzin, ... Journal of medicinal chemistry 54 (20), 7259-7267, 2011 | 27 | 2011 |
| Time‐Gated Detection of Cystathionine γ‐Lyase Activity and Inhibition with a Selective, Luminogenic Hydrogen Sulfide Sensor Y Yao, C Kong, L Yin, AD Jain, K Ratia, GRJ Thatcher, TW Moore, ... Chemistry–A European Journal 23 (4), 752-756, 2017 | 20 | 2017 |
| Synthesis and Evaluation of Noncovalent Naphthalene-Based KEAP1-NRF2 Inhibitors PR Lazzara, AD Jain, AC Maldonado, B Richardson, KJ Skowron, ... ACS Medicinal Chemistry Letters 11 (4), 521-527, 2020 | 18 | 2020 |
| Conjugate alkynylation of electrophilic double bonds. From regioselectivity to enantioselectivity G Blay, JR Pedro, A Sanz-Marco Synthesis 50 (17), 3281-3306, 2018 | 18 | 2018 |
| Desformylflustrabromine (dFBr) and [3H] dFBr-labeled binding sites in a nicotinic acetylcholine receptor AK Hamouda, ZJ Wang, DS Stewart, AD Jain, RA Glennon, JB Cohen Molecular Pharmacology 88 (1), 1-11, 2015 | 18 | 2015 |
| Palladium-catalyzed coupling reactions on functionalized 2-trifluoromethyl-4-chromenone scaffolds: synthesis of highly functionalized trifluoromethyl heterocycles J Izquierdo, AD Jain, SA Abdulkadir, GE Schiltz Synthesis 51 (06), 1342-1352, 2019 | 12 | 2019 |
| des-Formylflustrabromine (dFBr): A Structure–Activity Study on Its Ability To Potentiate the Action of Acetylcholine at α4β2 Nicotinic Acetylcholine Receptors M Dukat, A Jain, N German, R Ferrara-Pontoriero, Y Huang, Y Ma, ... ACS Chemical Neuroscience 9 (12), 2984-2996, 2018 | 8 | 2018 |
| Targeting pleckstrin-2/Akt signaling reduces proliferation in myeloproliferative neoplasm models X Han, Y Mei, RK Mishra, H Bi, AD Jain, GE Schiltz, B Zhao, M Sukhanova, ... The Journal of Clinical Investigation 133 (6), 2023 | 5 | 2023 |
| Substituted Heterocycles as c-MYC Targeting Agents GE Schiltz, RK Mishra, H Han, SA Abdulkadir, J Izquierdo-Ferrer, AD Jain US Patent WO 2,020,046,382 A1, 2020 | 2 | 2020 |
| Targeting Pleckstrin-2 for the Treatment of Myeloproliferative Neoplasms X Han, Y Mei, G Schiltz, R Mishra, A Jain, P Ji Blood 136, 10-11, 2020 | 1 | 2020 |
| Targeting pleckstrin-2 for the JAK2-STAT and PI3K-Akt pathways in cancer therapy X Han, Y Mei, GE Schiltz, RK Mishra, AD Jain, P Ji Cancer Research 79 (13_Supplement), 1287-1287, 2019 | 1 | 2019 |
| Proteolysis-targeting chimeric molecules (PROTACs) that induce degradation of c-MYC protein GE Schiltz, A Jain, H Han, SA Abdulkadir US Patent 11,890,346, 2024 | | 2024 |
| Substituted heterocycles as c-MYC targeting agents GE Schiltz, A Jain, H Han, SA Abdulkadir US Patent 11,420,957, 2022 | | 2022 |
| Targeting pleckstrin-2 for treating cancer P Ji, GE Schillz, RK Mishra, AD Jain US Patent App. 17/309,179, 2022 | | 2022 |
