| Experimental models for the discovery of novel anticonvulsant drugs: focus on pentylenetetrazole-induced seizures and associated memory deficits A Alachkar, SK Ojha, A Sadeq, A Adem, A Frank, H Stark, B Sadek Current pharmaceutical design 26 (15), 1693-1711, 2020 | 43 | 2020 |
| The histamine H3 receptor antagonist E159 reverses memory deficits induced by dizocilpine in passive avoidance and novel object recognition paradigm in rats A Alachkar, D Łażewska, K Kieć-Kononowicz, B Sadek Frontiers in Pharmacology 8, 709, 2017 | 40 | 2017 |
| Antagonism of histamine H3 receptors alleviates pentylenetetrazole-induced kindling and associated memory deficits by mitigating oxidative stress, central neurotransmitters … A Alachkar, S Azimullah, M Lotfy, E Adeghate, SK Ojha, R Beiram, ... Molecules 25 (7), 1575, 2020 | 29 | 2020 |
| Studies on anticonvulsant effects of novel histamine H3R antagonists in electrically and chemically induced seizures in rats A Alachkar, D Łażewska, G Latacz, A Frank, A Siwek, A Lubelska, ... International journal of molecular sciences 19 (11), 3386, 2018 | 28 | 2018 |
| Rational design of new multitarget histamine H3 receptor ligands as potential candidates for treatment of Alzheimer’s disease D Łażewska, M Bajda, M Kaleta, P Zaręba, A Doroz-Płonka, A Siwek, ... European Journal of Medicinal Chemistry 207, 112743, 2020 | 23 | 2020 |
| Histamine H3 receptor antagonist E177 attenuates amnesia induced by dizocilpine without modulation of anxiety-like behaviors in rats A Alachkar, N Khan, D Łażewska, K Kieć-Kononowicz, B Sadek Neuropsychiatric disease and treatment, 531-542, 2019 | 18 | 2019 |
| The neuroprotective effects of histamine H3 receptor antagonist E177 on pilocarpine-induced status epilepticus in rats A Alachkar, S Azimullah, SK Ojha, R Beiram, D Łażewska, ... Molecules 24 (22), 4106, 2019 | 16 | 2019 |
| Anticonvulsant evaluation of novel non-imidazole histamine H3R antagonists in different convulsion models in rats A Alachkar, G Latacz, A Siwek, A Lubelska, E Honkisz, A Gryboś, ... Pharmacology Biochemistry and Behavior 170, 14-24, 2018 | 10 | 2018 |
| Ameliorating effects of histamine H3 receptor antagonist E177 on acute pentylenetetrazole-induced memory impairments in rats A Alachkar, M Lotfy, E Adeghate, D Łażewska, K Kieć-Kononowicz, ... Behavioural Brain Research 405, 113193, 2021 | 8 | 2021 |
| ANTICONVULSANT AND PROCOGNITIVE EFFECT OF NONIMIDAZOLE HISTAMINE H3R RECEPTOR ANTAGONISTS/INVERSE AGONISTS IN EXPERIMENTAL ANIMAL MODELS AI Alachkar | | 2020 |
| THE HISTAMINE H-3 RECEPTOR ANTAGONIST E177 REVERSES AMNESIA INDUCED BY DIZOCILPINE IN PASSIVE AVOIDANCE PARADIGM AND NOVEL OBJECT RECOGNITION IN RATS A Alachkar, N Khan, D Lazewska, K Kiec-Kononowicz, B Sadek INFLAMMATION RESEARCH 67, S12-S12, 2018 | | 2018 |
Bassem Shaban SadekProfessor, Department of Pharmacology and Therapeutics, United Arab Emirates University在 uaeu.ac.ae 的电子邮件经过验证
