Histone acetylation of glucose-induced thioredoxin-interacting protein gene expression in pancreatic islets P Bompada, D Atac, C Luan, R Andersson, JD Omella, EO Laakso, ... The international journal of biochemistry & cell biology 81, 82-91, 2016 | 27 | 2016 |
Structural mechanism for inhibition of PP2A-B56α and oncogenicity by CIP2A K Pavic, N Gupta, JD Omella, R Derua, A Aakula, R Huhtaniemi, ... Nature communications 14 (1), 1143, 2023 | 22 | 2023 |
PPP2R4 dysfunction promotes KRAS-mutant lung adenocarcinoma development and mediates opposite responses to MEK and mTOR inhibition B Meeusen, EE Cortesi, JD Omella, A Sablina, JJ Ventura, V Janssens Cancer Letters 520, 57-67, 2021 | 13 | 2021 |
An okadaic acid fragment analogue prevents nicotine-induced resistance to cisplatin by recovering PP2A activity in non-small cell lung cancer cells RL Arribas, A Bordas, JD Omella, JL Cedillo, V Janssens, C Montiel, ... Bioorganic Chemistry 100, 103874, 2020 | 10 | 2020 |
Differential proteomic analysis of hepatocellular carcinomas from Ppp2r5d knockout mice and normal (knockout) livers C Lambrecht, GB Ferreira, JD Omella, L Libbrecht, R De Vos, R Derua, ... Cancer genomics & proteomics 17 (6), 669-685, 2020 | 7 | 2020 |
Regulation of nuclear receptor interacting protein 1 (NRIP1) gene expression in response to weight loss and exercise in humans Y De Marinis, J Sun, P Bompada, J Domènech Omella, C Luan, A Halu, ... Obesity 25 (8), 1400-1409, 2017 | 4 | 2017 |
The PPP2R1A cancer hotspot mutant p.R183W increases clofarabine resistance in uterine serous carcinoma cells by a gain-of-function mechanism M Remmerie, R Dok, Z Wang, JD Omella, S Alen, C Cokelaere, ... Cellular Oncology, 1-19, 2024 | | 2024 |
The tumor suppressive role of Protein Phosphatase 2A B56δ subunit in primary liver cancer J Domènech Omella | | 2023 |
A Novel Mouse Model of Combined Hepatocellular-Cholangiocarcinoma Induced by Diethylnitrosamine and Loss of Ppp2r5d J Domènech Omella, EE Cortesi, I Verbinnen, M Remmerie, H Wu, ... Cancers 15 (16), 4193, 2023 | | 2023 |
The therapeutic potential of clofarabine in type II uterine cancers is PPP2R1A hotspot mutant and cell-context dependent M Remmerie, R Dok, J Domènech Omella, C Cokelaere, S Nuyts, ... EMBO Workshop'Signaling regulation by Protein Phosphatases: Mechanisms and …, 2023 | | 2023 |
Silencing CNNM4 in cholangiocarcinoma inhibits tumoral progression by means of non-canonical ferroptosis M Mercado-Gómez, AE Giné, M Bravo, M Azkargorta, M Serrano-Macia, ... Journal of Hepatology 78, S544-S545, 2023 | | 2023 |
Molecular insights into the tumour suppressor role of Protein Phosphatase 2A B56delta complex in human liver, and its clinically relevant inhibition by Cancerous Inhibitor of PP2A J Domènech Omella, B Meeusen, E Cortesi, K Zwaenepoel, R Derua, ... Journal of Hepatology 77 (suppl 1), S637-S638, 2022 | | 2022 |
Therapeutic suitability of Small Activators of PP2A in sorafenib-and regorafenib-resistant HCC cell lines J Domènech Omella, E Dreesen, L Guffens, B Meeusen, M Ohlmeyer, ... Liver Cancer Summit 2022, Date: 2022/02/03-2022/02/05, Location: Estoril …, 2022 | | 2022 |
The tumor suppressive role of PP2A-B56δ phosphatase in liver: Mechanisms of inhibition and relevance in human HCC J Domènech Omella, B Meeusen, EE Cortesi, R Derua, K Zwaenepoel, ... LKI Oncoforum 2021, Location: Leuven, 2021 | | 2021 |
An okadaic acid fragment analogue prevents nicotine-induced chemoresistance to cisplatin by recovering the impaired PP2A activity in NSCLC R Lopez Arribas, A Bordas, J Domènech Omella, C Montiel, V Janssens, ... FEBS Advanced Course Europhosphatase 2019: From molecular mechanisms to …, 2019 | | 2019 |
On the tumor suppressive role of PP2A-B56delta in hepatocellular carcinoma J Domènech Omella, K Zwaenepoel, Y Hoorne, P Pauwels, R Derua, ... FEBS Advanced course Europhosphatase 2019: From molecular mechanisms to …, 2019 | | 2019 |
Histone acetylation and transcriptome mapping reveals distinct glucose-regulated genomic regions mediated by histone acetyltransferase p300 in pancreatic beta cells P Bompada, P Volkov, R Andersson, M Bysani, S Atanur, C Luan, ... European Association for the Study of Diabetes, Date: 2018/10/01-2018/10/05 …, 2018 | | 2018 |