Immunogenicity of CIGB‐230, a therapeutic DNA vaccine preparation, in HCV‐chronically infected individuals in a Phase I clinical trial L Alvarez‐Lajonchere, NH Shoukry, B Gra, Y Amador‐Cañizares, F Helle, ... Journal of viral hepatitis 16 (3), 156-167, 2009 | 121 | 2009 |
Regulation of hepatitis C virus genome replication by Xrn1 and microRNA-122 binding to individual sites in the 5′ untranslated region PA Thibault, A Huys, Y Amador-Cañizares, JE Gailius, DE Pinel, ... Journal of virology 89 (12), 6294-6311, 2015 | 99 | 2015 |
miR-122 does not impact recognition of the HCV genome by innate sensors of RNA but rather protects the 5′ end from the cellular pyrophosphatases, DOM3Z and DUSP11 Y Amador-Cañizares, A Bernier, JA Wilson, SM Sagan Nucleic acids research 46 (10), 5139-5158, 2018 | 65 | 2018 |
miR-122, small RNA annealing and sequence mutations alter the predicted structure of the Hepatitis C virus 5′ UTR RNA to stabilize and promote viral RNA accumulation Y Amador-Cañizares, M Panigrahi, A Huys, RD Kunden, HM Adams, ... Nucleic acids research 46 (18), 9776-9792, 2018 | 48 | 2018 |
Plasmid DNA recovery using size-exclusion and perfusion chromatography M Limonta, G Márquez, I Rey, M Pupo, O Ruiz, Y Amador-Canizares, ... Advanstar Communications, Inc., 2008 | 21 | 2008 |
HCV-specific immune responses induced by CIGB-230 in combination with IFN-α plus ribavirin Y Amador-Cañizares, G Martínez-Donato, L Álvarez-Lajonchere, ... World Journal of Gastroenterology: WJG 20 (1), 148, 2014 | 20 | 2014 |
Analysis of hepatitis C virus core encoding sequences in chronically infected patients reveals mutability, predominance, genetic history and potential impact on therapy of … EE González-Horta, J Marante, Y Amador-Cañizares, L Álvarezlajonchere, ... Transfusion 37, 52.1, 2011 | 15 | 2011 |
Toxicology and biodistribution study of CIGB-230, a DNA vaccine against hepatitis C virus D Bacardí, Y Amador-Cañizares, K Cosme, D Urquiza, J Suárez, ... Human & experimental toxicology 28 (8), 479-491, 2009 | 12 | 2009 |
Ultrastructural and immunological characterization of hepatitis C core protein–DNA plasmid complexes N Acosta-Rivero, Y Aguilera, V Falcon, J Poutou, A Musacchio, ... Am J Immunol 2 (3), 67-72, 2006 | 12 | 2006 |
Neutralizing antibodies and broad, functional T cell immune response following immunization with hepatitis C virus proteins-based vaccine formulation G Martinez-Donato, Y Amador-Cañizares, L Alvarez-Lajonchere, I Guerra, ... Vaccine 32 (15), 1720-1726, 2014 | 11 | 2014 |
Induction of IgA and sustained deficiency of cell proliferative response in chronic hepatitis C Y Amador-Cañizares, L Alvarez-Lajonchere, I Guerra, I Rodríguez-Alonso, ... World journal of gastroenterology: WJG 14 (44), 6844, 2008 | 7 | 2008 |
A chimeric protein encompassing hepatitis C virus epitopes is able to elicit both humoral and cell‐mediated immune responses in mice D Aguilar‐Noriega, L Alvarez‐Lajonchere, E Brown, FL Santana, ... Biotechnology and Applied Biochemistry 61 (6), 627-636, 2014 | 4 | 2014 |
Generation and characterization of recombinant vaccinia viruses expressing a hepatitis C virus Core protein, genotype 1b, individually or as a polyprotein L Alvarez-Lajonchere, I Guerra, Y Amador-Cañizares, R Frías, ... Biotecnología Aplicada 24 (3-4), 246-253, 2007 | 4 | 2007 |
Early interferon-based treatment after detection of persistent hepatitis C virus infection: a critical decision Y Amador-Canizares, S Duenas-Carrera Journal of Interferon & Cytokine Research 30 (11), 817-824, 2010 | 3 | 2010 |
Assessment of IL-28: rs12979860 and rs8099917 Polymorphisms in a Cohort of Cuban Chronic HCV Genotype 1b Patients DP Gardón, IA Guillen, JR Fernández, H Camacho, ZC Estevez, ... Journal of Biomolecular Techniques: JBT 28 (2), 80, 2017 | 2 | 2017 |
Respuesta inmune específica contra el virus de la hepatitis C en individuos crónicamente infectados y su modificación mediante intervenciones terapéuticas que incluyen la … Y Amador Cañizares Universidad de la Habana, Facultad de Biología, 2013 | 2 | 2013 |
Immunization with a recombinant fowlpox virus expressing a hepatitis C virus core–E1 polyprotein variant, protects mice and African green monkeys (Chlorocebus aethiops sabaeus … L Alvarez‐Lajonchere, Y Amador‐Cañizares, R Frías, Y Milian, ... Biotechnology and applied biochemistry 51 (2), 97-105, 2008 | 2 | 2008 |
Antígenos de vacuna quimérica contra el virus de la hepatitis c SD CARRERA, DA NORIEGA, YA CAÑIZARES, LALP DE LEÓN, ... | | 2017 |
Chimeric vaccine antigens against hepatitis C virus SD Carrera, DA Noriega, YA Cañizares, LALP de León, GM Donato, ... US Patent 9,676,825, 2017 | | 2017 |
Antígenos vacunales quiméricos contra el virus de la hepatitis c SD CARRERA, DA NORIEGA, YA CAÑIZARES, LALP DE LEÓN, ... | | 2014 |