PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis J Hou, R Zhao, W Xia, CW Chang, Y You, JM Hsu, L Nie, Y Chen, ... Nature cell biology 22 (10), 1264-1275, 2020 | 627 | 2020 |
Selective small molecule PARG inhibitor causes replication fork stalling and cancer cell death JH Houl, Z Ye, CA Brosey, LPF Balapiti-Modarage, S Namjoshi, A Bacolla, ... Nature communications 10 (1), 5654, 2019 | 94 | 2019 |
Cancer mutational burden is shaped by G4 DNA, replication stress and mitochondrial dysfunction A Bacolla, Z Ye, Z Ahmed, JA Tainer Progress in biophysics and molecular biology 147, 47-61, 2019 | 46 | 2019 |
Function and molecular mechanism of the DNA damage response in immunity and cancer immunotherapy Z Ye, Y Shi, SP Lees-Miller, JA Tainer Frontiers in immunology 12, 797880, 2021 | 43 | 2021 |
XRCC1 promotes replication restart, nascent fork degradation and mutagenic DNA repair in BRCA2-deficient cells BJ Eckelmann, A Bacolla, H Wang, Z Ye, EN Guerrero, W Jiang, R El-Zein, ... NAR cancer 2 (3), zcaa013, 2020 | 41 | 2020 |
PRL-3 activates mTORC1 in cancer progression Z Ye, AQO Al-Aidaroos, JE Park, HF Yuen, SD Zhang, A Gupta, Y Lin, ... Scientific reports 5 (1), 17046, 2015 | 35 | 2015 |
SLX4IP acts with SLX4 and XPF–ERCC1 to promote interstrand crosslink repair H Zhang, Z Chen, Y Ye, Z Ye, D Cao, Y Xiong, M Srivastava, X Feng, ... Nucleic acids research 47 (19), 10181-10201, 2019 | 34 | 2019 |
GRB2 enforces homology-directed repair initiation by MRE11 Z Ye, S Xu, Y Shi, A Bacolla, A Syed, D Moiani, CL Tsai, Q Shen, G Peng, ... Science Advances 7 (32), eabe9254, 2021 | 27 | 2021 |
Heritable pattern of oxidized DNA base repair coincides with pre-targeting of repair complexes to open chromatin A Bacolla, S Sengupta, Z Ye, C Yang, J Mitra, RB De-Paula, ML Hegde, ... Nucleic acids research 49 (1), 221-243, 2021 | 21 | 2021 |
PRL3 induces polyploid giant cancer cells eliminated by PRL3-zumab to reduce tumor relapse M Thura, Z Ye, AQ Al-Aidaroos, Q Xiong, JY Ong, A Gupta, J Li, K Guo, ... Communications biology 4 (1), 923, 2021 | 16 | 2021 |
Cholesterol-enriched membrane micro-domain deficiency induces doxorubicin resistance via promoting autophagy in breast cancer Y Shi, Z Ye, G Lu, N Yang, J Zhang, L Wang, J Cui, MA Del Pozo, Y Wu, ... Molecular Therapy-Oncolytics 23, 311-329, 2021 | 12 | 2021 |
PRL-3 dephosphorylates p38 MAPK to promote cell survival under stress Y Shi, S Xu, NYL Ngoi, Q Zeng, Z Ye Free Radical Biology and Medicine 177, 72-87, 2021 | 11 | 2021 |
Rag GTPases suppress PRL-3 degradation and predict poor clinical diagnosis of cancer patients with low PRL-3 mRNA expression Y Shi, S Xu, NYL Ngoi, Y Hui, Z Ye Biochemical and Biophysical Research Communications 576, 108-116, 2021 | 3 | 2021 |
Protein Tyrosine Phosphatase PRL-3: A Key Player in Cancer Signaling H Liu, X Li, Y Shi, Z Ye, X Cheng Biomolecules 14 (3), 342, 2024 | 2 | 2024 |
The Configuration of GRB2 in Protein Interaction and Signal Transduction D Wang, G Liu, Y Meng, H Chen, Z Ye, J Jing Biomolecules 14 (3), 259, 2024 | 2 | 2024 |
Discovery of novel macrocyclic derivatives as potent and selective cyclin-dependent kinase 2 inhibitors P Niu, Y Tao, Q Meng, Y Huang, S Li, K Ding, D Ma, Z Ye, M Fan Bioorganic & Medicinal Chemistry 104, 117711, 2024 | 1 | 2024 |
GRB2 stabilizes RAD51 at reversed replication forks suppressing genomic instability and innate immunity against cancer Z Ye, S Xu, Y Shi, X Cheng, Y Zhang, S Roy, S Namjoshi, MA Longo, ... Nature communications 15 (1), 2132, 2024 | 1 | 2024 |
GRB2 stabilizes RAD51 at reversed replication forks restricting genomic instability and associated innate immune response Z Ahmed, Z Ye, S Xu, Y Shi, X Cheng, Y Zhang, S Roy, S Namjoshi, ... Cancer Research 84 (6_Supplement), 6404-6404, 2024 | | 2024 |
Abstract A018: GRB2 acts at reversed forks in the BRCA2-RAD51-MRE11 axis: a therapeutic target and enabling predictive biomarker for PARP inhibitor-immunotherapy combination JA Tainer, K Schlacher, B Wang, G Peng, Z Ahmed Cancer Research 84 (1_Supplement), A018-A018, 2024 | | 2024 |
Advancements and Obstacles of PARP Inhibitors in Gastric Cancer H Chen, Y Hu, Z Zhuang, D Wang, Z Ye, J Jing, X Cheng Cancers 15 (21), 5114, 2023 | | 2023 |