A global genetic interaction network maps a wiring diagram of cellular function M Costanzo, B VanderSluis, EN Koch, A Baryshnikova, C Pons, G Tan, ... Science 353 (6306), aaf1420, 2016 | 1266 | 2016 |
Using networks to measure similarity between genes: association index selection JIF Bass, A Diallo, J Nelson, JM Soto, CL Myers, AJM Walhout Nature methods 10 (12), 1169, 2013 | 242 | 2013 |
A marine microbiome antifungal targets urgent-threat drug-resistant fungi F Zhang, M Zhao, DR Braun, SS Ericksen, JS Piotrowski, J Nelson, ... Science 370 (6519), 974-978, 2020 | 137 | 2020 |
Coculture of Marine Invertebrate-Associated Bacteria and Interdisciplinary Technologies Enable Biosynthesis and Discovery of a New Antibiotic, Keyicin N Adnani, MG Chevrette, SN Adibhatla, F Zhang, Q Yu, DR Braun, ... ACS chemical biology 12 (12), 3093-3102, 2017 | 129 | 2017 |
Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network JS Reece-Hoyes, C Pons, A Diallo, A Mori, S Shrestha, S Kadreppa, ... Molecular cell 51 (1), 116-127, 2013 | 99 | 2013 |
Unraveling the biology of a fungal meningitis pathogen using chemical genetics JCS Brown, J Nelson, B VanderSluis, R Deshpande, A Butts, S Kagan, ... Cell 159 (5), 1168-1187, 2014 | 89 | 2014 |
Functional annotation of chemical libraries across diverse biological processes JS Piotrowski, SC Li, R Deshpande, SW Simpkins, J Nelson, Y Yashiroda, ... Nature chemical biology 13 (9), 982, 2017 | 88 | 2017 |
A comparative genomic approach for identifying synthetic lethal interactions in human cancer R Deshpande, MK Asiedu, M Klebig, S Sutor, E Kuzmin, J Nelson, ... Cancer research 73 (20), 6128-6136, 2013 | 71 | 2013 |
Translocon Declogger Ste24 Protects against IAPP Oligomer-Induced Proteotoxicity C Kayatekin, A Amasino, G Gaglia, J Flannick, JM Bonner, S Fanning, ... Cell 173 (1), 62-73. e9, 2018 | 63 | 2018 |
Environmental robustness of the global yeast genetic interaction network M Costanzo, J Hou, V Messier, J Nelson, M Rahman, B VanderSluis, ... Science 372 (6542), 2021 | 57 | 2021 |
Accumulation of heme biosynthetic intermediates contributes to the antibacterial action of the metalloid tellurite EH Morales, CA Pinto, R Luraschi, CM Muñoz-Villagrán, FA Cornejo, ... Nature Communications 8, 15320, 2017 | 44 | 2017 |
Phytotoxic Responses of Soybean (Glycine max L.) to Botryodiplodin, a Toxin Produced by the Charcoal Rot Disease Fungus, Macrophomina phaseolina HK Abbas, N Bellaloui, AM Butler, JL Nelson, M Abou-Karam, WT Shier Toxins 12 (1), 25, 2020 | 28 | 2020 |
Chemical Genomics, Structure Elucidation, and in Vivo Studies of the Marine-Derived Anticlostridial Ecteinamycin TP Wyche, RFR Alvarenga, JS Piotrowski, MN Duster, SR Warrack, ... ACS Chemical Biology 12 (9), 2287-2295, 2017 | 27 | 2017 |
Chemical Genomics, Structure Elucidation, and in Vivo Studies of the Marine-Derived Anticlostridial Ecteinamyc in. TP Wyche, RFR Alvarenga, JS Piotrowski, MN Duster, SR Warrack, ... | 27 | 2017 |
Using BEAN-counter to quantify genetic interactions from multiplexed barcode sequencing experiments SW Simpkins, R Deshpande, J Nelson, SC Li, JS Piotrowski, HN Ward, ... Nat Protoc 14 (2), 415-440, 2019 | 23 | 2019 |
MOSAIC: a chemical-genetic interaction data repository and web resource for exploring chemical modes of action J Nelson, SW Simpkins, H Safizadeh, SC Li, JS Piotrowski, H Hirano, ... Bioinformatics 34 (7), 1251-1252, 2017 | 22 | 2017 |
Improving Measures of Chemical Structural Similarity Using Machine Learning on Chemical–Genetic Interactions H Safizadeh, SW Simpkins, J Nelson, SC Li, JS Piotrowski, M Yoshimura, ... Journal of chemical information and modeling, 2021 | 18 | 2021 |
A New Natural Product Analog of Blasticidin S Reveals Cellular Uptake Facilitated by the NorA Multidrug Transporter JR Davison, KM Lohith, X Wang, K Bobyk, SR Mandadapu, SL Lee, ... Antimicrobial Agents and Chemotherapy 61 (6), e02635-16, 2017 | 18 | 2017 |
Predicting bioprocess targets of chemical compounds through integration of chemical-genetic and genetic interactions SW Simpkins, J Nelson, R Deshpande, SC Li, JS Piotrowski, EH Wilson, ... PLoS computational biology 14 (10), e1006532, 2018 | 14 | 2018 |
Efficient strategies for screening large-scale genetic interaction networks R Deshpande, J Nelson, SW Simpkins, M Costanzo, JS Piotrowski, SC Li, ... bioRxiv, 159632, 2017 | 10 | 2017 |