Single-cell transcriptomic analysis of human lung provides insights into the pathobiology of pulmonary fibrosis PA Reyfman, JM Walter, N Joshi, KR Anekalla, AC McQuattie-Pimentel, ... American journal of respiratory and critical care medicine 199 (12), 1517-1536, 2019 | 1029 | 2019 |
Monocyte-derived alveolar macrophages drive lung fibrosis and persist in the lung over the life span AV Misharin, L Morales-Nebreda, PA Reyfman, CM Cuda, JM Walter, ... Journal of Experimental Medicine 214 (8), 2387-2404, 2017 | 899 | 2017 |
Alveolar macrophages N Joshi, JM Walter, AV Misharin Cellular immunology 330, 86-90, 2018 | 273 | 2018 |
A spatially restricted fibrotic niche in pulmonary fibrosis is sustained by M-CSF/M-CSFR signalling in monocyte-derived alveolar macrophages N Joshi, S Watanabe, R Verma, RP Jablonski, CI Chen, P Cheresh, ... European Respiratory Journal 55 (1), 2020 | 224 | 2020 |
The lung microenvironment shapes a dysfunctional response of alveolar macrophages in aging AC McQuattie-Pimentel, Z Ren, N Joshi, S Watanabe, T Stoeger, M Chi, ... The Journal of clinical investigation 131 (4), 2021 | 111 | 2021 |
Hepatocyte tissue factor activates the coagulation cascade in mice BP Sullivan, AK Kopec, N Joshi, H Cline, JA Brown, SC Bishop, ... Blood, The Journal of the American Society of Hematology 121 (10), 1868-1874, 2013 | 78 | 2013 |
RNA sequencing identifies novel translational biomarkers of kidney fibrosis FL Craciun, V Bijol, AK Ajay, P Rao, RK Kumar, J Hutchinson, O Hofmann, ... Journal of the American society of nephrology 27 (6), 1702-1713, 2016 | 72 | 2016 |
Fibrin (ogen) drives repair after acetaminophen-induced liver injury via leukocyte αMβ2 integrin-dependent upregulation of Mmp12 AK Kopec, N Joshi, H Cline-Fedewa, AV Wojcicki, JL Ray, BP Sullivan, ... Journal of hepatology 66 (4), 787-797, 2017 | 67 | 2017 |
Thrombin Inhibition with Dabigatran Protects against High-Fat Diet–Induced Fatty Liver Disease in Mice AK Kopec, N Joshi, KL Towery, KM Kassel, BP Sullivan, MJ Flick, ... Journal of Pharmacology and Experimental Therapeutics 351 (2), 288-297, 2014 | 67 | 2014 |
Platelets and protease-activated receptor-4 contribute to acetaminophen-induced liver injury in mice K Miyakawa, N Joshi, BP Sullivan, R Albee, C Brandenberger, ... Blood, The Journal of the American Society of Hematology 126 (15), 1835-1843, 2015 | 64 | 2015 |
Role of hemostatic factors in hepatic injury and disease: animal models de‐liver AK Kopec, N Joshi, JP Luyendyk Journal of Thrombosis and Haemostasis 14 (7), 1337-1349, 2016 | 55 | 2016 |
Coagulation‐driven platelet activation reduces cholestatic liver injury and fibrosis in mice N Joshi, AK Kopec, KM O'brien, KL Towery, H Cline‐Fedewa, KJ Williams, ... Journal of Thrombosis and Haemostasis 13 (1), 57-71, 2015 | 49 | 2015 |
Resetting proteostasis with ISRIB promotes epithelial differentiation to attenuate pulmonary fibrosis S Watanabe, NS Markov, Z Lu, R Piseaux Aillon, S Soberanes, ... Proceedings of the National Academy of Sciences 118 (20), e2101100118, 2021 | 48 | 2021 |
Multidimensional assessment of the host response in mechanically ventilated patients with suspected pneumonia JM Walter, Z Ren, T Yacoub, PA Reyfman, RD Shah, H Abdala-Valencia, ... American journal of respiratory and critical care medicine 199 (10), 1225-1237, 2019 | 36 | 2019 |
Fibrin deposition following bile duct injury limits fibrosis through an αMβ2-dependent mechanism N Joshi, AK Kopec, JL Ray, H Cline-Fedewa, A Nawabi, T Schmitt, ... Blood, The Journal of the American Society of Hematology 127 (22), 2751-2762, 2016 | 34 | 2016 |
Residual endotoxin induces primary graft dysfunction through ischemia/reperfusion-primed alveolar macrophages M Akbarpour, E Lecuona, SF Chiu, Q Wu, M Querrey, R Fernandez, ... The Journal of clinical investigation 130 (8), 4456-4469, 2020 | 28 | 2020 |
Impaired phagocytic function in CX3CR1+ tissue‐resident skeletal muscle macrophages prevents muscle recovery after influenza A virus‐induced pneumonia in … CE Runyan, LC Welch, E Lecuona, M Shigemura, L Amarelle, ... Aging cell 19 (9), e13180, 2020 | 26 | 2020 |
Von Willebrand factor deficiency reduces liver fibrosis in mice N Joshi, AK Kopec, JL Ray, H Cline-Fedewa, DJ Groeneveld, T Lisman, ... Toxicology and applied pharmacology 328, 54-59, 2017 | 22 | 2017 |
The sphingosine kinase 1 inhibitor, PF543, mitigates pulmonary fibrosis by reducing lung epithelial cell mtDNA damage and recruitment of fibrogenic monocytes P Cheresh, SJ Kim, LS Huang, S Watanabe, N Joshi, KJN Williams, M Chi, ... International journal of molecular sciences 21 (16), 5595, 2020 | 20 | 2020 |
Targeting phospholipase D4 attenuates kidney fibrosis P Trivedi, RK Kumar, A Iyer, S Boswell, C Gerarduzzi, VP Dadhania, ... Journal of the American Society of Nephrology 28 (12), 3579-3589, 2017 | 20 | 2017 |