| A novel automated lazy learning QSAR (ALL-QSAR) approach: method development, applications, and virtual screening of chemical databases using validated ALL-QSAR models S Zhang, A Golbraikh, S Oloff, H Kohn, A Tropsha Journal of chemical information and modeling 46 (5), 1984-1995, 2006 | 269 | 2006 |
| Synthesis and Anticonvulsant Activities of N-Benzyl-2-acetamidopropionamide Derivatives D Choi, JP Stables, H Kohn Journal of medicinal chemistry 39 (9), 1907-1916, 1996 | 214 | 1996 |
| Application of predictive QSAR models to database mining: identification and experimental validation of novel anticonvulsant compounds M Shen, C Béguin, A Golbraikh, JP Stables, H Kohn, A Tropsha Journal of medicinal chemistry 47 (9), 2356-2364, 2004 | 184 | 2004 |
| Quantitative Structure−Activity Relationship Analysis of Functionalized Amino Acid Anticonvulsant Agents Using k Nearest Neighbor and Simulated Annealing PLS … M Shen, A LeTiran, Y Xiao, A Golbraikh, H Kohn, A Tropsha Journal of medicinal chemistry 45 (13), 2811-2823, 2002 | 183 | 2002 |
| Lacosamide, a novel anti-convulsant drug, shows efficacy with a wide safety margin in rodent models for epilepsy T Stöhr, HJ Kupferberg, JP Stables, D Choi, RH Harris, H Kohn, N Walton, ... Epilepsy research 74 (2-3), 147-154, 2007 | 178 | 2007 |
| Role of the C-10 substituent in mitomycin C-1− DNA bonding VS Li, D Choi, Z Wang, LS Jimenez, M Tang, H Kohn Journal of the American Chemical Society 118 (10), 2326-2331, 1996 | 145 | 1996 |
| Effect of structural modification of the hydantoin ring on anticonvulsant activity S Cortes, ZK Liao, D Watson, H Kohn Journal of medicinal chemistry 28 (5), 601-606, 1985 | 145 | 1985 |
| Translational stroke research: vision and opportunities F Bosetti, JI Koenig, C Ayata, SA Back, K Becker, JP Broderick, ... Stroke 48 (9), 2632-2637, 2017 | 137 | 2017 |
| The inefficiency of incisions of ecteinascidin 743–DNA adducts by the UvrABC nuclease and the unique structural feature of the DNA adducts can be used to explain the repair … M Zewail-Foote, VS Li, H Kohn, D Bearss, M Guzman, LH Hurley Chemistry & Biology 8 (11), 1033-1049, 2001 | 126 | 2001 |
| Transcription termination factor rho: the site of bicyclomycin inhibition in Escherichia coli A Zwiefka, H Kohn, WR Widger Biochemistry 32 (14), 3564-3570, 1993 | 126 | 1993 |
| The 1.9 Å Crystal Structure of Alanine Racemase from Mycobacterium tuberculosis Contains a Conserved Entryway into the Active Site, P LeMagueres, H Im, J Ebalunode, U Strych, MJ Benedik, JM Briggs, ... Biochemistry 44 (5), 1471-1481, 2005 | 116 | 2005 |
| Functionalized amino acid anticonvulsants: synthesis and pharmacological evaluation of conformationally restricted analogues A LeTiran, JP Stables, H Kohn Bioorganic & medicinal chemistry 9 (10), 2693-2708, 2001 | 108 | 2001 |
| Studies on the bonding specificity for mitomycin C-DNA monoalkylation processes VS Li, H Kohn Journal of the American Chemical Society 113 (1), 275-283, 1991 | 102 | 1991 |
| The molecular basis for the mode of action of bicyclomycin H Kohn, W Widger Current Drug Targets-Infectious Disorders 5 (3), 273-295, 2005 | 97 | 2005 |
| Useful tools for biomolecule isolation, detection, and identification: acylhydrazone-based cleavable linkers KD Park, R Liu, H Kohn Chemistry & biology 16 (7), 763-772, 2009 | 95 | 2009 |
| Methylated cyclodextrin and a cyclodextrin polymer as catalysts in selective anisole chlorination R Breslow, H Kohn, B Siegel Tetrahedron Letters 17 (20), 1645-1646, 1976 | 88 | 1976 |
| Structural mechanism of inhibition of the Rho transcription termination factor by the antibiotic bicyclomycin E Skordalakes, AP Brogan, BS Park, H Kohn, JM Berger Structure 13 (1), 99-109, 2005 | 82 | 2005 |
| Preparation and anticonvulsant activity of a series of functionalized. alpha.-heteroatom-substituted amino acids H Kohn, KN Sawhney, P LeGall, DW Robertson, JD Leander Journal of medicinal chemistry 34 (8), 2444-2452, 1991 | 79 | 1991 |
| Functionalized DL-amino acid derivatives. Potent new agents for the treatment of epilepsy JD Conley, H Kohn Journal of medicinal chemistry 30 (3), 567-574, 1987 | 77 | 1987 |
| Preparation and anticonvulsant activity of a series of functionalized. alpha.-aromatic and. alpha.-heteroaromatic amino acids H Kohn, KN Sawhney, P LeGall, JD Conley, DW Robertson, JD Leander Journal of medicinal chemistry 33 (3), 919-926, 1990 | 74 | 1990 |
