Adverse outcome pathways: opportunities, limitations and open questions M Leist, A Ghallab, R Graepel, R Marchan, R Hassan, SH Bennekou, ... Archives of Toxicology 91, 3477-3505, 2017 | 339 | 2017 |
Toxicogenomics directory of chemically exposed human hepatocytes M Grinberg, RM Stöber, K Edlund, E Rempel, P Godoy, R Reif, A Widera, ... Archives of toxicology 88, 2261-2287, 2014 | 150 | 2014 |
Chemokine receptor antagonists: a novel therapeutic approach in allergic diseases J Elsner, SE Escher, U Forssmann Allergy 59 (12), 1243-1258, 2004 | 135 | 2004 |
Collaborative development of predictive toxicology applications B Hardy, N Douglas, C Helma, M Rautenberg, N Jeliazkova, V Jeliazkov, ... Journal of cheminformatics 2, 1-29, 2010 | 133 | 2010 |
Inhibition of CD26/dipeptidyl peptidase IV enhances CCL11/eotaxin-mediated recruitment of eosinophils in vivo U Forssmann, C Stoetzer, M Stephan, C Kruschinski, T Skripuletz, ... The Journal of Immunology 181 (2), 1120-1127, 2008 | 130 | 2008 |
Towards grouping concepts based on new approach methodologies in chemical hazard assessment: the read-across approach of the EU-ToxRisk project SE Escher, H Kamp, SH Bennekou, A Bitsch, C Fisher, R Graepel, ... Archives of toxicology 93, 3643-3667, 2019 | 122 | 2019 |
Evaluation of inhalation TTC values with the database RepDose SE Escher, I Tluczkiewicz, M Batke, A Bitsch, C Melber, ED Kroese, ... Regulatory Toxicology and Pharmacology 58 (2), 259-274, 2010 | 85 | 2010 |
Internationalization of read-across as a validated new approach method (NAM) for regulatory toxicology C Rovida, T Barton-Maclaren, E Benfenati, F Caloni, PC Chandrasekera, ... Altex 37 (4), 579, 2020 | 76 | 2020 |
Legacy data sharing to improve drug safety assessment: the eTOX project F Sanz, F Pognan, T Steger-Hartmann, C Díaz, eTOX, M Cases, M Pastor, ... Nature reviews Drug discovery 16 (12), 811-812, 2017 | 74 | 2017 |
Comparing in vitro human liver models to in vivo human liver using RNA-Seq R Gupta, Y Schrooders, D Hauser, M van Herwijnen, W Albrecht, ... Archives of toxicology 95, 573-589, 2021 | 71 | 2021 |
Hemofiltrate CC chemokines with unique biochemical properties: HCC-1/CCL14a and HCC-2/CCL15 U Forssmann, HJ Mägert, K Adermann, SE Escher, WG Forssmann Journal of leukocyte biology 70 (3), 357-366, 2001 | 60 | 2001 |
Improvement of the Cramer classification for oral exposure using the database TTC RepDose–a strategy description I Tluczkiewicz, HE Buist, MT Martin, I Mangelsdorf, SE Escher Regulatory Toxicology and Pharmacology 61 (3), 340-350, 2011 | 58 | 2011 |
Quantum proteolytic activation of chemokine CCL15 by neutrophil granulocytes modulates mononuclear cell adhesiveness R Richter, R Bistrian, S Escher, WG Forssmann, J Vakili, R Henschler, ... The Journal of immunology 175 (3), 1599-1608, 2005 | 52 | 2005 |
Hemofiltrate CC chemokine 1 [9-74] causes effective internalization of CCR5 and is a potent inhibitor of R5-tropic human immunodeficiency virus type 1 strains in primary T … J Münch, L Ständker, S Pöhlmann, F Baribaud, A Papkalla, ... Antimicrobial agents and chemotherapy 46 (4), 982-990, 2002 | 51 | 2002 |
Solution Structure of the Human CC Chemokine 2: A Monomeric Representative of the CC Chemokine Subtype, H Sticht, SE Escher, K Schweimer, WG Forssmann, P Rösch, K Adermann Biochemistry 38 (19), 5995-6002, 1999 | 50 | 1999 |
Toxicology ontology perspectives B Hardy, G Apic, P Carthew, D Clark, D Cook, I Dix, S Escher, J Hastings, ... ALTEX-Alternatives to animal experimentation 29 (2), 139-156, 2012 | 47 | 2012 |
Data quality assessment for in silico methods: a survey of approaches and needs M Nendza, T Aldenberg, E Benfenati, R Benigni, MTD Cronin, S Escher, ... | 46* | 2010 |
Setting the stage for next-generation risk assessment with non-animal approaches: the EU-ToxRisk project experience MJ Moné, G Pallocca, SE Escher, T Exner, M Herzler, SH Bennekou, ... Archives of Toxicology 94, 3581-3592, 2020 | 43 | 2020 |
Development of a roadmap for action on new approach methodologies in risk assessment SE Escher, F Partosch, S Konzok, P Jennings, M Luijten, A Kienhuis, ... EFSA Supporting Publications 19 (6), 7341E, 2022 | 41 | 2022 |
The application of new HARD-descriptor available from the CORAL software to building up NOAEL models AP Toropova, AA Toropov, M Marzo, SE Escher, JL Dorne, N Georgiadis, ... Food and Chemical Toxicology 112, 544-550, 2018 | 41 | 2018 |