The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints R Fredriksson, MC Lagerström, LG Lundin, HB Schiöth Molecular pharmacology 63 (6), 1256-1272, 2003 | 3931 | 2003 |
Structural diversity of G protein-coupled receptors and significance for drug discovery MC Lagerström, HB Schiöth Nature reviews Drug discovery 7 (4), 339-357, 2008 | 1861 | 2008 |
Neuronal atlas of the dorsal horn defines its architecture and links sensory input to transcriptional cell types M Häring, A Zeisel, H Hochgerner, P Rinwa, JET Jakobsson, ... Nature neuroscience 21 (6), 869-880, 2018 | 382 | 2018 |
Seven evolutionarily conserved human rhodopsin G protein‐coupled receptors lacking close relatives R Fredriksson, PJ Höglund, DEI Gloriam, MC Lagerström, HB Schiöth FEBS letters 554 (3), 381-388, 2003 | 379 | 2003 |
The human and mouse repertoire of the adhesion family of G-protein-coupled receptors TK Bjarnadóttir, R Fredriksson, PJ Höglund, DE Gloriam, MC Lagerström, ... Genomics 84 (1), 23-33, 2004 | 313 | 2004 |
VGLUT2-dependent sensory neurons in the TRPV1 population regulate pain and itch MC Lagerström, K Rogoz, B Abrahamsen, E Persson, B Reinius, ... Neuron 68 (3), 529-542, 2010 | 245 | 2010 |
The Secretin GPCRs Descended from the Family of Adhesion GPCRs KJV Nordström, MC Lagerström, LMJ Wallér, R Fredriksson, HB Schiöth Molecular biology and evolution 26 (1), 71-84, 2009 | 142 | 2009 |
There exist at least 30 human G-protein-coupled receptors with long Ser/Thr-rich N-termini R Fredriksson, DEI Gloriam, PJ Höglund, MC Lagerström, HB Schiöth Biochemical and biophysical research communications 301 (3), 725-734, 2003 | 141 | 2003 |
Association of feather colour with constitutively active melanocortin 1 receptors in chicken MK Ling, MC Lagerström, R Fredriksson, R Okimoto, NI Mundy, ... European Journal of Biochemistry 270 (7), 1441-1449, 2003 | 129 | 2003 |
The G protein–coupled receptor subset of the chicken genome MC Lagerström, AR Hellström, DE Gloriam, TP Larsson, HB Schiöth, ... PLoS computational biology 2 (6), e54, 2006 | 128 | 2006 |
Novel human G protein‐coupled receptors with long N‐terminals containing GPS domains and Ser/Thr‐rich regions R Fredriksson, MC Lagerström, PJ Höglund, HB Schiöth FEBS letters 531 (3), 407-414, 2002 | 117 | 2002 |
Synaptic changes induced by melanocortin signalling V Caruso, MC Lagerström, PK Olszewski, R Fredriksson, HB Schiöth Nature Reviews Neuroscience 15 (2), 98-110, 2014 | 95 | 2014 |
Cloning, tissue distribution, pharmacology and three-dimensional modelling of melanocortin receptors 4 and 5 in rainbow trout suggest close evolutionary relationship of these … T Haitina, J Klovins, J Andersson, R Fredriksson, MC Lagerström, ... Biochemical Journal 380 (2), 475-486, 2004 | 90 | 2004 |
Nociceptor-expressed ephrin-B2 regulates inflammatory and neuropathic pain J Zhao, G Yuan, CM Cendan, MA Nassar, MC Lagerström, K Kullander, ... Molecular pain 6, 1744-8069-6-77, 2010 | 65 | 2010 |
Restricted cortical and amygdaloid removal of vesicular glutamate transporter 2 in preadolescent mice impacts dopaminergic activity and neuronal circuitry of higher brain function Å Wallén-Mackenzie, K Nordenankar, K Fejgin, MC Lagerström, ... Journal of Neuroscience 29 (7), 2238-2251, 2009 | 63 | 2009 |
Spinal cord interneurons expressing the gastrin-releasing peptide receptor convey itch through VGLUT2-mediated signaling B Aresh, FB Freitag, S Perry, E Blümel, J Lau, MCM Franck, ... Pain 158 (5), 945-961, 2017 | 59 | 2017 |
Origin of the prolactin-releasing hormone (PRLH) receptors: evidence of coevolution between PRLH and a redundant neuropeptide Y receptor during vertebrate evolution MC Lagerström, R Fredriksson, TK Bjarnadóttir, D Fridmanis, T Holmquist, ... Genomics 85 (6), 688-703, 2005 | 57 | 2005 |
Midbrain gene screening identifies a new mesoaccumbal glutamatergic pathway and a marker for dopamine cells neuroprotected in Parkinson’s disease T Viereckel, S Dumas, CJA Smith-Anttila, B Vlcek, Z Bimpisidis, ... Scientific Reports 6 (1), 35203, 2016 | 55 | 2016 |
High affinity agonistic metal ion binding sites within the melanocortin 4 receptor illustrate conformational change of transmembrane region 3 MC Lagerström, J Klovins, R Fredriksson, D Fridmanis, T Haitina, ... Journal of Biological Chemistry 278 (51), 51521-51526, 2003 | 54 | 2003 |
Multimodal use of calcitonin gene-related peptide and substance P in itch and acute pain uncovered by the elimination of vesicular glutamate transporter 2 from transient … K Rogoz, HH Andersen, MC Lagerström, K Kullander Journal of Neuroscience 34 (42), 14055-14068, 2014 | 52 | 2014 |