NAADP mobilizes Ca2+ from reserve granules, lysosome-related organelles, in sea urchin eggs GC Churchill, Y Okada, JM Thomas, AA Genazzani, S Patel, A Galione Cell 111 (5), 703-708, 2002 | 563 | 2002 |
Molecular properties of inositol 1, 4, 5-trisphosphate receptors. S Patel, SK Joseph, AP Thomas Cell calcium 25 (3), 247, 1999 | 544 | 1999 |
Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling E Brailoiu, D Churamani, X Cai, MG Schrlau, GC Brailoiu, X Gao, ... Journal of Cell Biology 186 (2), 201-209, 2009 | 464 | 2009 |
Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP P Gomez-Suaga, B Luzon-Toro, D Churamani, L Zhang, D Bloor-Young, ... Human molecular genetics 21 (3), 511-525, 2012 | 358 | 2012 |
Acidic calcium stores open for business: expanding the potential for intracellular Ca2+ signaling S Patel, R Docampo Trends in cell biology 20 (5), 277-286, 2010 | 283 | 2010 |
Probing the complexities of astrocyte calcium signaling E Shigetomi, S Patel, BS Khakh Trends in cell biology 26 (4), 300-312, 2016 | 279 | 2016 |
Organelle selection determines agonist-specific Ca2+ signals in pancreatic acinar and β cells M Yamasaki, R Masgrau, AJ Morgan, GC Churchill, S Patel, SJH Ashcroft, ... Journal of Biological Chemistry 279 (8), 7234-7240, 2004 | 253 | 2004 |
Direct mobilisation of lysosomal Ca2+ triggers complex Ca2+ signals BS Kilpatrick, ER Eden, AH Schapira, CE Futter, S Patel Journal of cell science 126 (1), 60-66, 2013 | 209 | 2013 |
Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition LN Hockey, BS Kilpatrick, ER Eden, Y Lin-Moshier, GC Brailoiu, E Brailoiu, ... Journal of Cell Science 128 (2), 232-238, 2015 | 202 | 2015 |
Convergent regulation of the lysosomal two‐pore channel‐2 by Mg2+, NAADP, PI(3,5)P2 and multiple protein kinases A Jha, M Ahuja, S Patel, E Brailoiu, S Muallem The EMBO journal 33 (5), 501-511, 2014 | 197 | 2014 |
Photoaffinity Labeling of Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Targets in Mammalian Cells*♦ Y Lin-Moshier, TF Walseth, D Churamani, SM Davidson, JT Slama, ... Journal of Biological Chemistry 287 (4), 2296-2307, 2012 | 197 | 2012 |
Coordination of Ca2+ signalling by NAADP S Patel, GC Churchill, A Galione Trends in biochemical sciences 26 (8), 482-489, 2001 | 188 | 2001 |
Sperm deliver a new second messenger: NAADP GC Churchill, JS O'Neill, R Masgrau, S Patel, JM Thomas, AA Genazzani, ... Current biology 13 (2), 125-128, 2003 | 187 | 2003 |
An NAADP-gated two-pore channel targeted to the plasma membrane uncouples triggering from amplifying Ca2+ signals E Brailoiu, T Rahman, D Churamani, DL Prole, GC Brailoiu, R Hooper, ... Journal of Biological Chemistry 285 (49), 38511-38516, 2010 | 185 | 2010 |
Role of NAADP and cADPR in the induction and maintenance of agonist-evoked Ca2+ spiking in mouse pancreatic acinar cells M Yamasaki, JM Thomas, GC Churchill, C Garnham, AM Lewis, ... Current biology 15 (9), 874-878, 2005 | 173 | 2005 |
Function and dysfunction of two-pore channels S Patel Science signaling 8 (384), re7-re7, 2015 | 166 | 2015 |
Decorin activates the epidermal growth factor receptor and elevates cytosolic Ca2+ in A431 carcinoma cells S Patel, M Santra, DJ McQuillan, RV Iozzo, AP Thomas Journal of Biological Chemistry 273 (6), 3121-3124, 1998 | 147 | 1998 |
Agonist-mediated switching of ion selectivity in TPC2 differentially promotes lysosomal function S Gerndt, CC Chen, YK Chao, Y Yuan, S Burgstaller, A Scotto Rosato, ... Elife 9, e54712, 2020 | 146 | 2020 |
An ancestral deuterostome family of two-pore channels mediates nicotinic acid adenine dinucleotide phosphate-dependent calcium release from acidic organelles E Brailoiu, R Hooper, X Cai, GC Brailoiu, MV Keebler, NJ Dun, ... Journal of Biological Chemistry 285 (5), 2897-2901, 2010 | 143 | 2010 |
Nicotinic acid adenine dinucleotide phosphate (NAADP) regulates autophagy in cultured astrocytes GJS Pereira, H Hirata, GM Fimia, LG Do Carmo, C Bincoletto, SW Han, ... Journal of Biological Chemistry 286 (32), 27875-27881, 2011 | 141 | 2011 |