CDK9 inhibitors in acute myeloid leukemia S Boffo, A Damato, L Alfano, A Giordano Journal of Experimental & Clinical Cancer Research 37, 1-10, 2018 | 148 | 2018 |
Molecular mechanism of 17-allylamino-17-demethoxygeldanamycin (17-AAG)-induced AXL receptor tyrosine kinase degradation GP Krishnamoorthy, T Guida, L Alfano, E Avilla, M Santoro, F Carlomagno, ... Journal of Biological Chemistry 288 (24), 17481-17494, 2013 | 62 | 2013 |
Depletion of the RNA binding protein HNRNPD impairs homologous recombination by inhibiting DNA-end resection and inducing R-loop accumulation L Alfano, A Caporaso, A Altieri, M Dell’Aquila, C Landi, L Bini, F Pentimalli, ... Nucleic Acids Research 47 (8), 4068-4085, 2019 | 49 | 2019 |
NONO regulates the intra-S-phase checkpoint in response to UV radiation L Alfano, C Costa, A Caporaso, A Altieri, P Indovina, M Macaluso, ... Oncogene 35 (5), 567-576, 2016 | 35 | 2016 |
Abrogating G2/M checkpoint through WEE1 inhibition in combination with chemotherapy as a promising therapeutic approach for mesothelioma P Indovina, E Marcelli, D Di Marzo, N Casini, IM Forte, F Giorgi, L Alfano, ... Cancer biology & therapy 15 (4), 380-388, 2014 | 33 | 2014 |
RET is a heat shock protein 90 (HSP90) client protein and is knocked down upon HSP90 pharmacological block L Alfano, T Guida, L Provitera, G Vecchio, M Billaud, M Santoro, ... The Journal of Clinical Endocrinology & Metabolism 95 (7), 3552-3557, 2010 | 31 | 2010 |
RBL2/p130 is a direct AKT target and is required to induce apoptosis upon AKT inhibition in lung cancer and mesothelioma cell lines F Pentimalli, IM Forte, L Esposito, P Indovina, CA Iannuzzi, L Alfano, ... Oncogene 37 (27), 3657-3671, 2018 | 30 | 2018 |
Genomic analysis reveals association of specific SNPs with athletic performance and susceptibility to injuries in professional soccer players R La Montagna, R Canonico, L Alfano, E Bucci, S Boffo, L Staiano, ... Journal of cellular physiology 235 (3), 2139-2148, 2020 | 16 | 2020 |
HUR protects NONO from degradation by mir320, which is induced by p53 upon UV irradiation L Alfano, C Costa, A Caporaso, D Antonini, A Giordano, F Pentimalli Oncotarget 7 (47), 78127, 2016 | 15 | 2016 |
Hydrocortisone attenuates cyclosporin A‐induced nephrotoxicity in rats R Ciarcia, S Damiano, F Fiorito, G Granato, F Pagnini, V Mastellone, ... Journal of cellular biochemistry 113 (3), 997-1004, 2012 | 14 | 2012 |
HSP90 identified by a proteomic approach as druggable target to reverse platinum resistance in ovarian cancer R Lombardi, M Sonego, B Pucci, L Addi, F Iannelli, F Capone, L Alfano, ... Molecular Oncology 15 (4), 1005-1023, 2021 | 11 | 2021 |
NONO ubiquitination is mediated by FBW7 and GSK3 β via a degron lost upon chromosomal rearrangement in cancer L Alfano, A Caporaso, A Altieri, C Costa, IM Forte, CA Iannuzzi, D Barone, ... Journal of Cellular Physiology 233 (5), 4338-4344, 2018 | 11 | 2018 |
SMART (single molecule analysis of resection tracks) technique for assessing DNA end-resection in response to DNA damage A Altieri, M Dell’Aquila, F Pentimalli, A Giordano, A Luigi Bio-protocol 10 (15), e3701-e3701, 2020 | 7 | 2020 |
DNA fiber assay upon treatment with ultraviolet radiations A Luigi, A Giordano, F Pentimalli Bio-protocol 7 (11), e2301-e2301, 2017 | 5 | 2017 |
The hydrophilic extract from a new tomato genotype (named DHO) kills cancer cell lines through the modulation of the DNA damage response induced by Campthotecin treatment D Barone, CA Iannuzzi, IM Forte, MC Ragosta, M Cuomo, M Dell’Aquila, ... Frontiers in Oncology 13, 1117262, 2023 | 1 | 2023 |
CDK9-55 guides the anaphase-promoting complex/cyclosome (APC/C) in choosing the DNA repair pathway choice L Alfano, CA Iannuzzi, D Barone, IM Forte, MC Ragosta, M Cuomo, ... Oncogene 43 (17), 1263-1273, 2024 | | 2024 |
Abstract B011: CDK9-55 guides the anaphase-promoting complex/cyclosome (APC/C) in choosing the DNA repair pathway by affecting the UFL1 ubiquitination L Alfano Cancer Research 84 (1_Supplement), B011-B011, 2024 | | 2024 |
Pharmacological inhibition of CDK4/6 impairs diffuse pleural mesothelioma 3D spheroid growth and reduces viability of cisplatin-resistant cells A Costa, IM Forte, F Pentimalli, CA Iannuzzi, L Alfano, F Capone, ... Frontiers in Oncology 14, 2024 | | 2024 |
CDK9-55 guides the anaphase-promoting complex/cyclosome (APC/C) in choosing the DNA repair pathway by affecting the UFL1 ubiquitination L Alfano CANCER RESEARCH 84 (1), 2024 | | 2024 |
Changliang Shan, Nankai University, China A Sule, G Chen, A Giordano, L Alfano, D Barone, CA Iannuzzi, IM Forte, ... | | 2023 |