| In Vivo Comparison of the Pharmacodynamic Targets for Echinocandin Drugs against Candida Species D Andes, DJ Diekema, MA Pfaller, J Bohrmuller, K Marchillo, A Lepak Antimicrobial agents and chemotherapy 54 (6), 2497-2506, 2010 | 252 | 2010 |
| Time Course Global Gene Expression Analysis of an In Vivo Candida Biofilm JE Nett, AJ Lepak, K Marchillo, DR Andes The Journal of infectious diseases 200 (2), 307-313, 2009 | 206 | 2009 |
| Antifungal pharmacokinetics and pharmacodynamics AJ Lepak, DR Andes Cold Spring Harbor perspectives in medicine 5 (5), a019653, 2015 | 139 | 2015 |
| Animal models in the pharmacokinetic/pharmacodynamic evaluation of antimicrobial agents M Zhao, AJ Lepak, DR Andes Bioorganic & medicinal chemistry 24 (24), 6390-6400, 2016 | 117 | 2016 |
| Pharmacodynamic Target Evaluation of a Novel Oral Glucan Synthase Inhibitor, SCY-078 (MK-3118), Using an In Vivo Murine Invasive Candidiasis Model AJ Lepak, K Marchillo, DR Andes Antimicrobial Agents and Chemotherapy 59 (2), 1265-1272, 2015 | 100 | 2015 |
| Impact of Antimicrobial Dosing Regimen on Evolution of Drug Resistance In Vivo: Fluconazole and Candida albicans D Andes, A Forrest, A Lepak, J Nett, K Marchillo, L Lincoln Antimicrobial agents and chemotherapy 50 (7), 2374-2383, 2006 | 97 | 2006 |
| Pharmacodynamic optimization for treatment of invasive Candida auris infection AJ Lepak, M Zhao, EL Berkow, SR Lockhart, DR Andes Antimicrobial Agents and Chemotherapy 61 (8), 10.1128/aac. 00791-17, 2017 | 93 | 2017 |
| Isavuconazole (BAL4815) pharmacodynamic target determination in an in vivo murine model of invasive pulmonary aspergillosis against wild-type and cyp51 mutant isolates of … AJ Lepak, K Marchillo, J VanHecker, DR Andes Antimicrobial agents and chemotherapy 57 (12), 6284-6289, 2013 | 90 | 2013 |
| In Vivo Pharmacokinetics and Pharmacodynamics of ZTI-01 (Fosfomycin for Injection) in the Neutropenic Murine Thigh Infection Model against Escherichia coli … AJ Lepak, M Zhao, B VanScoy, DS Taylor, E Ellis-Grosse, PG Ambrose, ... Antimicrobial Agents and Chemotherapy 61 (6), 10.1128/aac. 00476-17, 2017 | 89 | 2017 |
| Fungal sepsis: optimizing antifungal therapy in the critical care setting A Lepak, D Andes Critical care clinics 27 (1), 123-147, 2011 | 89 | 2011 |
| Posaconazole Pharmacodynamic Target Determination against Wild-Type and Cyp51 Mutant Isolates of Aspergillus fumigatus in an In Vivo Model of Invasive … AJ Lepak, K Marchillo, J VanHecker, DR Andes Antimicrobial agents and chemotherapy 57 (1), 579-585, 2013 | 81 | 2013 |
| In Vivo Pharmacokinetics and Pharmacodynamics of APX001 against Candida spp. in a Neutropenic Disseminated Candidiasis Mouse Model M Zhao, AJ Lepak, B VanScoy, JC Bader, K Marchillo, J Vanhecker, ... Antimicrobial agents and chemotherapy 62 (4), 10.1128/aac. 02542-17, 2018 | 79 | 2018 |
| Pharmacodynamic evaluation of rezafungin (CD101) against Candida auris in the neutropenic mouse invasive candidiasis model AJ Lepak, M Zhao, DR Andes Antimicrobial agents and chemotherapy 62 (11), 10.1128/aac. 01572-18, 2018 | 67 | 2018 |
| Isavuconazole Pharmacodynamic Target Determination for Candida Species in an In Vivo Murine Disseminated Candidiasis Model AJ Lepak, K Marchillo, J VanHecker, D Diekema, DR Andes Antimicrobial agents and chemotherapy 57 (11), 5642-5648, 2013 | 64 | 2013 |
| Comparative pharmacodynamics of the new oxazolidinone tedizolid phosphate and linezolid in a neutropenic murine Staphylococcus aureus pneumonia model AJ Lepak, K Marchillo, S Pichereau, WA Craig, DR Andes Antimicrobial agents and chemotherapy 56 (11), 5916-5922, 2012 | 59 | 2012 |
| A Simple Approach for Estimating Gene Expression in Candida albicans Directly from a Systemic Infection Site D Andes, A Lepak, A Pitula, K Marchillo, J Clark The Journal of infectious diseases 192 (5), 893-900, 2005 | 59 | 2005 |
| Impact of MIC Range for Pseudomonas aeruginosa and Streptococcus pneumoniae on the Ceftolozane In Vivo Pharmacokinetic/Pharmacodynamic Target AJ Lepak, A Reda, K Marchillo, J Van Hecker, WA Craig, D Andes Antimicrobial Agents and Chemotherapy 58 (10), 6311-6314, 2014 | 58 | 2014 |
| Pharmacodynamics of a long-acting echinocandin, CD101, in a neutropenic invasive-candidiasis murine model using an extended-interval dosing design AJ Lepak, M Zhao, B VanScoy, PG Ambrose, DR Andes Antimicrobial Agents and Chemotherapy 62 (2), 10.1128/aac. 02154-17, 2018 | 56 | 2018 |
| Time Course of Microbiologic Outcome and Gene Expression in Candida albicans during and following In Vitro and In Vivo Exposure to Fluconazole A Lepak, J Nett, L Lincoln, K Marchillo, D Andes Antimicrobial agents and chemotherapy 50 (4), 1311-1319, 2006 | 56 | 2006 |
| In Vivo Pharmacodynamic Target Assessment of Delafloxacin against Staphylococcus aureus, Streptococcus pneumoniae, and Klebsiella pneumoniae in a Murine … AJ Lepak, DR Andes Antimicrobial Agents and Chemotherapy 60 (8), 4764-4769, 2016 | 53 | 2016 |
