Mechanosensing by the lamina protects against nuclear rupture, DNA damage, and cell-cycle arrest S Cho, M Vashisth, A Abbas, S Majkut, K Vogel, Y Xia, IL Ivanovska, ... Developmental cell 49 (6), 920-935. e5, 2019 | 248 | 2019 |
Nuclear failure, DNA damage, and cell cycle disruption after migration through small pores: a brief review CR Pfeifer, M Vashisth, Y Xia, DE Discher Essays in Biochemistry 63 (5), 569-577, 2019 | 28 | 2019 |
Gaussian curvature dilutes the nuclear lamina, favoring nuclear rupture, especially at high strain rate CR Pfeifer, MP Tobin, S Cho, M Vashisth, LJ Dooling, LL Vazquez, ... Nucleus 13 (1), 130-144, 2022 | 26 | 2022 |
Cooperative phagocytosis of solid tumours by macrophages triggers durable anti-tumour responses LJ Dooling, JC Andrechak, BH Hayes, S Kadu, W Zhang, R Pan, ... Nature Biomedical Engineering 7 (9), 1081-1096, 2023 | 20 | 2023 |
Scaling concepts in ‘omics: Nuclear lamin-B scales with tumor growth and often predicts poor prognosis, unlike fibrosis M Vashisth, S Cho, J Irianto, Y Xia, M Wang, B Hayes, D Wieland, R Wells, ... Proceedings of the National Academy of Sciences 118 (48), e2112940118, 2021 | 17 | 2021 |
Nuclear mechanoprotection: From tissue atlases as blueprints to distinctive regulation of nuclear lamins M Wang, I Ivanovska, M Vashisth, DE Discher APL bioengineering 6 (2), 2022 | 12 | 2022 |
Confinement plus myosin-II suppression maximizes heritable loss of chromosomes, as revealed by live-cell ChReporters BH Hayes, PK Zhu, M Wang, CR Pfeifer, Y Xia, S Phan, JC Andrechak, ... Journal of cell science 136 (11), jcs260753, 2023 | 7 | 2023 |
Cooperative phagocytosis underlies macrophage immunotherapy of solid tumours and initiates a broad anti-tumour IgG response JC Andrechak, LJ Dooling, BH Hayes, S Kadu, W Zhang, R Pan, ... biorxiv, 2022.01. 01.474150, 2022 | 4 | 2022 |
Manipulating the mechanics of extracellular matrix to study effects on the nucleus and its structure Y Xia, S Cho, M Vashisth, IL Ivanovska, PCDP Dingal, DE Discher Methods 157, 3-14, 2019 | 4 | 2019 |
Heterogeneous strains in tissue suppress collagen degradation by collagenases K Saini, M Tewari, S Cho, M Vashisth, A Jalil, JC Andrechak, A Kasznel, ... Biophysical Journal 121 (3), 492a, 2022 | 2 | 2022 |
Confinement with Myosin-II suppression increases heritable loss of chromosomes, using live-cell ChReporters BH Hayes, PK Zhu, M Wang, CR Pfeifer, Y Xia, S Phan, JC Andrechak, ... BioRxiv, 2023.02. 25.530049, 2023 | 1 | 2023 |
Tension-suppressed degradation of collagen controls tissue stiffness scaling with fibrillar collagen K Saini, S Cho, M Tewari, A Jalil, M Wang, M Vashisth, A Kasznel, ... Biophysical Journal 122 (3), 87a, 2023 | 1 | 2023 |
Scaling concepts in’omics: nuclear lamin-B scales with tumor growth and predicts poor prognosis, whereas fibrosis can be pro-survival M Vashisth, S Cho, J Irianto, Y Xia, M Wang, B Hayes, F Jafarpour, ... bioRxiv, 2021.02. 25.432860, 2021 | 1 | 2021 |
Solid Tumor Cures by Complete Disruption of the CD47: SIRPα Macrophage Checkpoint, Tumor Opsonization, and ‘Phagocytic Feedback’ LJ Dooling, JC Andrechak, BH Hayes, S Kadu, R Pan, MP Tobin, ... Biophysical Journal 120 (3), 89a, 2021 | 1 | 2021 |
Heterogeneously Strained Tissue Collagen Resists Collagenase Degradation where Strains are High K Saini, M Tewari, S Cho, A Jalil, J Irianto, M Vashisth, CR Pfeifer, ... Biophysical Journal 120 (3), 102a, 2021 | 1 | 2021 |
Heterogeneous strains in tissue collagen show that high strains locally suppress degradation by collagenase K Saini, M Tiwari, S Cho, A Jalil, M Vashisth, J Irianto, J Andrechak, ... bioRxiv, 2021.02. 07.430141, 2021 | 1 | 2021 |
Heterogeneously Strained Tissue Collagen Resists Collagenase Degradation Where Strains are High K Saini, M Tewari, S Cho, A Jalil, J Irianto, M Vashisth, C Pfeifer, ... Biophysical Journal 118 (3), 398a, 2020 | 1 | 2020 |
Molecular consequences of acute versus chronic CDK12 loss in prostate carcinoma nominates distinct therapeutic strategies S Frank, T Persse, I Coleman, A Bankhead, D Li, N DeSarkar, D Wilson, ... bioRxiv, 2024 | | 2024 |
A Highlights from MBoC Selection: Differences in cell shape, motility, and growth reflect chromosomal number variations that can be visualized with live-cell ChReporters MP Tobin, CR Pfeifer, PK Zhu, BH Hayes, M Wang, M Vashisth, Y Xia, ... Molecular Biology of the Cell 34 (13), 2023 | | 2023 |
Differences in cell shape, motility, and growth reflect chromosomal number variations that can be visualized with live-cell ChReporters MP Tobin, CR Pfeifer, PK Zhu, BH Hayes, M Wang, M Vashisth, Y Xia, ... Molecular Biology of the Cell 34 (13), br19, 2023 | | 2023 |