| Identification of known drugs that act as inhibitors of NF-κB signaling and their mechanism of action SC Miller, R Huang, S Sakamuru, SJ Shukla, MS Attene-Ramos, P Shinn, ... Biochemical pharmacology 79 (9), 1272-1280, 2010 | 315 | 2010 |
| Mitochondrial membrane potential assay S Sakamuru, MS Attene-Ramos, M Xia High-throughput screening assays in toxicology, 17-22, 2016 | 244 | 2016 |
| Modelling the Tox21 10 K chemical profiles for in vivo toxicity prediction and mechanism characterization R Huang, M Xia, S Sakamuru, J Zhao, SA Shahane, M Attene-Ramos, ... Nature communications 7 (1), 10425, 2016 | 229 | 2016 |
| Analysis of eight oil spill dispersants using rapid, in vitro tests for endocrine and other biological activity RS Judson, MT Martin, DM Reif, KA Houck, TB Knudsen, DM Rotroff, ... Environmental science & technology 44 (15), 5979-5985, 2010 | 220 | 2010 |
| Chemical genomics profiling of environmental chemical modulation of human nuclear receptors R Huang, M Xia, MH Cho, S Sakamuru, P Shinn, KA Houck, DJ Dix, ... Environmental health perspectives 119 (8), 1142-1148, 2011 | 210 | 2011 |
| Tox21Challenge to build predictive models of nuclear receptor and stress response pathways as mediated by exposure to environmental chemicals and drugs R Huang, M Xia, DT Nguyen, T Zhao, S Sakamuru, J Zhao, SA Shahane, ... Frontiers in Environmental Science 3, 85, 2016 | 202 | 2016 |
| Existing drugs as broad-spectrum and potent inhibitors for Zika virus by targeting NS2B-NS3 interaction Z Li, M Brecher, YQ Deng, J Zhang, S Sakamuru, B Liu, R Huang, ... Cell research 27 (8), 1046-1064, 2017 | 197 | 2017 |
| Development and validation of a computational model for androgen receptor activity NC Kleinstreuer, P Ceger, ED Watt, M Martin, K Houck, P Browne, ... Chemical research in toxicology 30 (4), 946-964, 2017 | 188 | 2017 |
| Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway R Huang, S Sakamuru, MT Martin, DM Reif, RS Judson, KA Houck, ... Scientific reports 4 (1), 5664, 2014 | 167 | 2014 |
| High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death JT Fox, S Sakamuru, R Huang, N Teneva, SO Simmons, M Xia, RR Tice, ... Proceedings of the National Academy of Sciences 109 (14), 5423-5428, 2012 | 136 | 2012 |
| Identification of clinically used drugs that activate pregnane X receptors SJ Shukla, S Sakamuru, R Huang, TA Moeller, P Shinn, D VanLeer, ... Drug Metabolism and Disposition 39 (1), 151-159, 2011 | 113 | 2011 |
| Population-Based in Vitro Hazard and Concentration–Response Assessment of Chemicals: The 1000 Genomes High-Throughput Screening Study N Abdo, M Xia, CC Brown, O Kosyk, R Huang, S Sakamuru, YH Zhou, ... Environmental health perspectives 123 (5), 458-466, 2015 | 110 | 2015 |
| Application of a homogenous membrane potential assay to assess mitochondrial function S Sakamuru, X Li, MS Attene-Ramos, R Huang, J Lu, L Shou, M Shen, ... Physiological genomics 44 (9), 495-503, 2012 | 91 | 2012 |
| Systematic study of mitochondrial toxicity of environmental chemicals using quantitative high throughput screening MS Attene-Ramos, R Huang, S Sakamuru, KL Witt, GC Beeson, L Shou, ... Chemical research in toxicology 26 (9), 1323-1332, 2013 | 78 | 2013 |
| Characterization of three human cell line models for high‐throughput neuronal cytotoxicity screening ZB Tong, H Hogberg, D Kuo, S Sakamuru, M Xia, L Smirnova, T Hartung, ... Journal of Applied Toxicology 37 (2), 167-180, 2017 | 75 | 2017 |
| Erythrosin B is a potent and broad-spectrum orthosteric inhibitor of the flavivirus NS2B-NS3 protease Z Li, S Sakamuru, R Huang, M Brecher, CA Koetzner, J Zhang, H Chen, ... Antiviral research 150, 217-225, 2018 | 71 | 2018 |
| Limited chemical structural diversity found to modulate thyroid hormone receptor in the Tox21 chemical library K Paul-Friedman, M Martin, KM Crofton, CW Hsu, S Sakamuru, J Zhao, ... Environmental health perspectives 127 (9), 097009, 2019 | 60 | 2019 |
| Characterization of environmental chemicals with potential for DNA damage using isogenic DNA repair‐deficient chicken DT40 cell lines KN Yamamoto, K Hirota, K Kono, S Takeda, S Sakamuru, M Xia, R Huang, ... Environmental and molecular mutagenesis 52 (7), 547-561, 2011 | 58 | 2011 |
| Cell-based high-throughput screening for aromatase inhibitors in the Tox21 10K library S Chen, JH Hsieh, R Huang, S Sakamuru, LY Hsin, M Xia, KR Shockley, ... Toxicological Sciences 147 (2), 446-457, 2015 | 47 | 2015 |
| Identification of small molecule compounds that inhibit the HIF-1 signaling pathway M Xia, K Bi, R Huang, MH Cho, S Sakamuru, SC Miller, H Li, Y Sun, ... Molecular cancer 8, 1-13, 2009 | 41 | 2009 |
