Ivermectin sensitivity in collies is associated with a deletion mutation of the mdr1 gene KL Mealey, SA Bentjen, JM Gay, GH Cantor Pharmacogenetics and Genomics 11 (8), 727-733, 2001 | 573 | 2001 |
Breed distribution and history of canine mdr1-1Δ, a pharmacogenetic mutation that marks the emergence of breeds from the collie lineage MW Neff, KR Robertson, AK Wong, N Safra, KW Broman, M Slatkin, ... Proceedings of the National Academy of Sciences 101 (32), 11725-11730, 2004 | 273 | 2004 |
Therapeutic implications of the MDR‐1 gene KL Mealey Journal of veterinary pharmacology and therapeutics 27 (5), 257-264, 2004 | 259 | 2004 |
The genomic architecture of segmental duplications and associated copy number variants in dogs TJ Nicholas, Z Cheng, M Ventura, K Mealey, EE Eichler, JM Akey Genome research 19 (3), 491-499, 2009 | 188 | 2009 |
Breed distribution of the ABCB1-1Δ (multidrug sensitivity) polymorphism among dogs undergoing ABCB1 genotyping KL Mealey, KM Meurs Journal of the American Veterinary Medical Association 233 (6), 921-924, 2008 | 133 | 2008 |
Pharmacogenetic and metabolic differences between dog breeds: their impact on canine medicine and the use of the dog as a preclinical animal model S Fleischer, M Sharkey, K Mealey, EA Ostrander, M Martinez The AAPS journal 10, 110-119, 2008 | 133 | 2008 |
Increased toxicity of P-glycoprotein-substrate chemotherapeutic agents in a dog with the MDR1 deletion mutation associated with ivermectin sensitivity KL Mealey, NC Northrup, SA Bentjen Journal of the American Veterinary Medical Association 223 (10), 1453-1455, 2003 | 132 | 2003 |
Frequency of the mutant MDR1 allele associated with ivermectin sensitivity in a sample population of collies from the northwestern United States KL Mealey, SA Bentjen, DK Waiting American Journal of Veterinary Research 63 (4), 479-481, 2002 | 113 | 2002 |
Loperamide toxicity in a collie with the MDR1 mutation associated with ivermectin sensitivity LL Sartor, SA Bentjen, L Trepanier, KL Mealey Journal of Veterinary Internal Medicine 18 (1), 117-118, 2004 | 110 | 2004 |
The pharmacogenomics of P‐glycoprotein and its role in veterinary medicine M Martinez, S Modric, M Sharkey, L Troutman, L Walker, K Mealey Journal of veterinary pharmacology and therapeutics 31 (4), 285-300, 2008 | 105 | 2008 |
Systemic absorption of amitriptyline and buspirone after oral and transdermal administration to healthy cats KL Mealey, KE Peck, BS Bennett, RK Sellon, GR Swinney, K Melzer, ... Journal of veterinary internal medicine 18 (1), 43-46, 2004 | 98 | 2004 |
P‐glycoprotein mediated drug interactions in animals and humans with cancer KL Mealey, J Fidel Journal of veterinary internal medicine 29 (1), 1-6, 2015 | 97 | 2015 |
The effects of inhibiting cytochrome P450 3A, p‐glycoprotein, and gastric acid secretion on the oral bioavailability of methadone in dogs B KUKANICH, BDX Lascelles, AM Aman, KL Mealey, MG Papich Journal of Veterinary Pharmacology and Therapeutics 28 (5), 461-466, 2005 | 92 | 2005 |
Doxycycline induces expression of P glycoprotein in MCF-7 breast carcinoma cells KL Mealey, R Barhoumi, RC Burghardt, S Safe, DT Kochevar Antimicrobial agents and chemotherapy 46 (3), 755-761, 2002 | 86 | 2002 |
Pharmacokinetics of flunixin meglumine in donkeys, mules, and horses M Coakley, KE Peck, TS Taylor, NS Matthews, KL Mealey American Journal of Veterinary Research 60 (11), 1441-1444, 1999 | 83 | 1999 |
Frequency of the mutant MDR1 allele associated with multidrug sensitivity in a sample of herding breed dogs living in Australia KL Mealey, KA Munyard, SA Bentjen Veterinary parasitology 131 (3-4), 193-196, 2005 | 80 | 2005 |
Frequency of the mutant MDR1 allele associated with multidrug sensitivity in a sample of collies from France C Hugnet, SA Bentjen, KL Mealey Journal of Veterinary Pharmacology and Therapeutics 27 (4), 227-229, 2004 | 77 | 2004 |
Molecular genetic basis for fluoroquinolone-induced retinal degeneration in cats CJ Ramirez, JD Minch, JM Gay, SM Lahmers, DJ Guerra, GJ Haldorson, ... Pharmacogenetics and genomics 21 (2), 66-75, 2011 | 75 | 2011 |
Tramadol metabolism to O-desmethyl tramadol (M1) and N-desmethyl tramadol (M2) by dog liver microsomes: species comparison and identification of responsible canine cytochrome P450s TE Perez, KL Mealey, TL Grubb, SA Greene, MH Court Drug Metabolism and Disposition 44 (12), 1963-1972, 2016 | 74 | 2016 |
Ivermectin toxicity in an Australian Shepherd dog with the MDR1 mutation associated with ivermectin sensitivity in Collies OL Nelson, E Carsten, SA Bentjen, KL Mealey Journal of veterinary internal medicine 17 (3), 354-356, 2003 | 73 | 2003 |