Targeting RNA polymerase I with an oral small molecule CX-5461 inhibits ribosomal RNA synthesis and solid tumor growth D Drygin, A Lin, J Bliesath, CB Ho, SE O'Brien, C Proffitt, M Omori, ... Cancer research 71 (4), 1418-1430, 2011 | 626 | 2011 |
Targeting the nucleolus for cancer intervention JE Quin, JR Devlin, D Cameron, KM Hannan, RB Pearson, RD Hannan Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1842 (6), 802-816, 2014 | 279 | 2014 |
UBF levels determine the number of active ribosomal RNA genes in mammals E Sanij, G Poortinga, K Sharkey, S Hung, TP Holloway, J Quin, E Robb, ... The Journal of cell biology 183 (7), 1259-1274, 2008 | 249 | 2008 |
Inhibition of RNA polymerase I transcription initiation by CX-5461 activates non-canonical ATM/ATR signaling J Quin, KT Chan, JR Devlin, DP Cameron, J Diesch, C Cullinane, J Ahern, ... Oncotarget 7 (31), 49800, 2016 | 110 | 2016 |
Inhibition of Pol I transcription treats murine and human AML by targeting the leukemia-initiating cell population N Hein, DP Cameron, KM Hannan, NYN Nguyen, CY Fong, J Sornkom, ... Blood, The Journal of the American Society of Hematology 129 (21), 2882-2895, 2017 | 87 | 2017 |
ADAR RNA modifications, the epitranscriptome and innate immunity J Quin, J Sedmík, D Vukić, A Khan, LP Keegan, MA O’Connell Trends in biochemical sciences 46 (9), 758-771, 2021 | 83 | 2021 |
Major transcriptional changes observed in the Fulani, an ethnic group less susceptible to malaria JE Quin, I Bujila, M Cherif, GS Sanou, Y Qu, M Vafa Homann, A Rolicka, ... Elife 6, e29156, 2017 | 44 | 2017 |
The nucleolus and ribosomal genes in aging and senescence N Hein, E Sanij, J Quin, KM Hannan, A Ganley, RD Hannan Senescence, 2012 | 38 | 2012 |
Epigenetics and malaria susceptibility/protection: A missing piece of the puzzle C Arama, JE Quin, B Kouriba, AK Östlund Farrants, M Troye-Blomberg, ... Frontiers in Immunology 9, 1733, 2018 | 31 | 2018 |
Gut commensal Limosilactobacillus reuteri induces atypical memory-like phenotype in human dendritic cells in vitro G Lasaviciute, M Barz, M van Der Heiden, C Arasa, K Tariq, J Quin, ... Gut microbes 14 (1), 2045046, 2022 | 9 | 2022 |
What will studies of Fulani individuals naturally exposed to malaria teach us about protective immunity to malaria? M Troye‐Blomberg, C Arama, J Quin, I Bujila, AK Östlund Farrants Scandinavian Journal of Immunology 92 (4), e12932, 2020 | 8 | 2020 |
The chromatin‐remodeling complexes B‐WICH and NuRD regulate ribosomal transcription in response to glucose A Rolicka, Y Guo, A Gañez Zapater, K Tariq, J Quin, A Vintermist, ... The FASEB Journal 34 (8), 10818-10834, 2020 | 7 | 2020 |
Malaria-derived hemozoin alters chromatin remodelling and skews dendritic cell responses to subsequent bacterial infections G Lasaviciute, K Tariq, A Sugathan, J Quin, I Bujila, O Skorokhod, ... bioRxiv, 2024.03. 18.585548, 2024 | 1 | 2024 |
Changes in ADAR1 activity during Plasmodium infection contribute to protection from malaria. JE Quin, E Kopel, R Gawish, M Eidelman, D Vukić, P Linhartová, ... bioRxiv, 2023.12. 07.570604, 2023 | | 2023 |
Lactobacilli-mediated dampening of pro-inflammatory T-cell immune responses-is this due to epigenetic alterations in the dendritic cells? G Lasaviciute, J Quin, OAK Farrants, E Sverremark-Ekstrom EUROPEAN JOURNAL OF IMMUNOLOGY 48, 120-121, 2018 | | 2018 |
The chromatin remodelling complex B-WICH is required for transcriptional activation of the ribosomal transcription by glucose stimulation. A Rolicka, Y Guo, A Gañez-Zapater, J Quin, A Vintermist, F Sadeghifar, ... | | 2018 |
A method of classification and treatment R Pearson, RD HANNAN, E SANIJ, KE SHEPPARD, KM HANNAN, ... | | 2017 |
Bioinformatics Core Facility 1. Development of bioinformatics methods for radiogenomics approaches in cancer research CP Spielvogel | | |