An unstructured initiation site is required for efficient proteasome-mediated degradation S Prakash, L Tian, KS Ratliff, RE Lehotzky, A Matouschek Nature structural & molecular biology 11 (9), 830-837, 2004 | 528 | 2004 |
ATP-dependent proteases degrade their substrates by processively unraveling them from the degradation signal C Lee, MP Schwartz, S Prakash, M Iwakura, A Matouschek Molecular cell 7 (3), 627-637, 2001 | 505 | 2001 |
USP7 small-molecule inhibitors interfere with ubiquitin binding L Kategaya, P Di Lello, L Rougé, R Pastor, KR Clark, J Drummond, ... Nature 550 (7677), 534-538, 2017 | 287 | 2017 |
Lack of a robust unfoldase activity confers a unique level of substrate specificity to the universal AAA protease FtsH C Herman, S Prakash, CZ Lu, A Matouschek, CA Gross Molecular cell 11 (3), 659-669, 2003 | 204 | 2003 |
Ubiquitination in the regulation of inflammatory cell death and cancer PE Cockram, M Kist, S Prakash, SH Chen, IE Wertz, D Vucic Cell Death & Differentiation 28 (2), 591-605, 2021 | 190 | 2021 |
Defining the geometry of the two-component proteasome degron T Inobe, S Fishbain, S Prakash, A Matouschek Nature chemical biology 7 (3), 161-167, 2011 | 179 | 2011 |
Protein unfolding in the cell S Prakash, A Matouschek Trends in biochemical sciences 29 (11), 593-600, 2004 | 178 | 2004 |
Substrate selection by the proteasome during degradation of protein complexes S Prakash, T Inobe, AJ Hatch, A Matouschek Nature chemical biology 5 (1), 29-36, 2009 | 152 | 2009 |
Controlling a single protein in a nanopore through electrostatic traps Mohammad, S Prakash, A Matouschek, L Movileanu Journal of the American Chemical Society 130 (12), 4081-4088, 2008 | 151 | 2008 |
Rad23 escapes degradation because it lacks a proteasome initiation region S Fishbain, S Prakash, A Herrig, S Elsasser, A Matouschek Nature communications 2 (1), 192, 2011 | 110 | 2011 |
Concurrent translocation of multiple polypeptide chains through the proteasomal degradation channel C Lee, S Prakash, A Matouschek Journal of Biological Chemistry 277 (38), 34760-34765, 2002 | 86 | 2002 |
ATP-dependent proteases differ substantially in their ability to unfold globular proteins P Koodathingal, NE Jaffe, DA Kraut, S Prakash, S Fishbain, C Herman, ... Journal of biological chemistry 284 (28), 18674-18684, 2009 | 85 | 2009 |
Targeted degradation via direct 26S proteasome recruitment C Bashore, S Prakash, MC Johnson, RJ Conrad, IA Kekessie, SJ Scales, ... Nature Chemical Biology 19 (1), 55-63, 2023 | 38 | 2023 |
Allosteric N-WASP activation by an inter-SH3 domain linker in Nck J Okrut, S Prakash, Q Wu, MJS Kelly, J Taunton Proceedings of the National Academy of Sciences 112 (47), E6436-E6445, 2015 | 38 | 2015 |
To degrade or release: ubiquitin-chain remodeling DA Kraut, S Prakash, A Matouschek Trends in cell biology 17 (9), 419-421, 2007 | 35 | 2007 |
Primary amine tethered small molecules promote the degradation of X-linked inhibitor of apoptosis protein W den Besten, K Verma, S Yamazoe, N Blaquiere, W Phung, ... Journal of the American Chemical Society 143 (28), 10571-10575, 2021 | 8 | 2021 |
Constitutive protein degradation induces acute cell death via proteolysis products SH Chen, S Prakash, E Helgason, CL Gilchrist, LR Kenner, R Srinivasan, ... bioRxiv, 2023.02. 06.527237, 2023 | 1 | 2023 |
After load reduction therapy with nitroprusside in chronic severe aortic regurgitation. A non invasive assessment. M Durairaj, SN Handekar, HL Kher, S Prakash, GR Narayanan Indian heart j, 1980 | 1 | 1980 |
Prevalence of hypertension with reversible risk factors in railway employees–A sample report CK Das, S Prakash, P Barapatre, AK Das, MM Pathak, G Chakraborty Indian Heart Journal 70, S11, 2018 | | 2018 |
Multifaceted presentations of ictal syncope CK Das, A Minz, S Prakash, MS Tripathy, GK Chakraborty Indian Heart Journal 70, S87, 2018 | | 2018 |