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peng he
peng he
在 tsinghua.edu.cn 的电子邮件经过验证 - 首页
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年份
Synthesis and Biological Evaluation of B-Cell Lymphoma 6 Inhibitors of N-Phenyl-4-pyrimidinamine Derivatives Bearing Potent Activities against Tumor Growth
W Guo, Y Xing, Q Zhang, J Xie, D Huang, H Gu, P He, M Zhou, S Xu, ...
Journal of medicinal chemistry 63 (2), 676-695, 2020
272020
Discovery of 2-Amino-3-cyanothiophene derivatives as potent STAT3 inhibitors for the treatment of osteosarcoma growth and metastasis
W Jin, T Zhang, W Zhou, P He, Y Sun, S Hu, H Chen, X Ma, Y Peng, Z Yi, ...
Journal of Medicinal Chemistry 65 (9), 6710-6728, 2022
202022
Discovery of YH677 as a cancer stemness inhibitor that suppresses triple-negative breast cancer growth and metastasis by regulating the TGFβ signaling pathway
Y Zhang, J Chen, D Mi, J Ling, H Li, P He, N Liu, Q Chen, Y Chen, ...
Cancer Letters 560, 216142, 2023
172023
Discovery of a Novel Potent STAT3 Inhibitor HP590 with Dual p-Tyr705/Ser727 Inhibitory Activity for Gastric Cancer Treatment
P He, Y Miao, Y Sun, A Bian, W Jin, H Chen, J Ye, J He, Y Peng, H Gu, ...
Journal of Medicinal Chemistry 65 (19), 12650-12674, 2022
142022
Discovery of the Highly Selective and Potent STAT3 Inhibitor for Pancreatic Cancer Treatment
H Chen, A Bian, W Zhou, Y Miao, J Ye, J Li, P He, Q Zhang, Y Sun, Z Sun, ...
ACS Central Science 10 (3), 579-594, 2024
122024
Discovery of a highly potent and orally bioavailable STAT3 dual phosphorylation inhibitor for pancreatic cancer treatment
P He, A Bian, Y Miao, W Jin, H Chen, J He, L Li, Y Sun, J Ye, M Liu, Z Yi, ...
Journal of Medicinal Chemistry 65 (22), 15487-15511, 2022
112022
Discovery of a potent and oral available complex I OXPHOS inhibitor that abrogates tumor growth and circumvents MEKi resistance
P He, J Feng, X Xia, Y Sun, J He, T Guan, Y Peng, X Zhang, M Liu, ...
Journal of Medicinal Chemistry 66 (9), 6047-6069, 2023
102023
Research on function and mechanisms of a novel small molecule WG 449E for hypertrophic scar
T Shao, W Tang, Y Li, D Gao, K Lv, P He, Y Song, S Gao, M Liu, Y Chen, ...
Journal of the European Academy of Dermatology and Venereology 34 (3), 608-618, 2020
102020
Discovery of pyrimidinediamine derivatives as potent methuosis inducers for the treatment of triple-negative breast cancer
J He, L Wang, DZ Mi, T Guan, W Liu, P He, H Gu, Y Li, Y Peng, AQ Jia, ...
Journal of Medicinal Chemistry 66 (11), 7421-7437, 2023
32023
Discovery of 1, 5-diaryl-1, 2, 4-triazole derivatives as myoferlin inhibitors and their antitumor effects in pancreatic cancer
H Gu, T Zhang, Y Li, Y He, T Guan, W Kan, P He, Z Yi, Y Chen
Future Medicinal Chemistry 14 (20), 1425-1440, 2022
32022
Recent advances of small molecular regulators targeting G protein-coupled receptors family for oncology immunotherapy
P He, W Zhou, M Liu, Y Chen
Current Topics in Medicinal Chemistry 19 (16), 1464-1483, 2019
32019
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