Self-organized cerebral organoids with human-specific features predict effective drugs to combat Zika virus infection M Watanabe, JE Buth, N Vishlaghi, L de la Torre-Ubieta, J Taxidis, ... Cell reports 21 (2), 517-532, 2017 | 341 | 2017 |
25-Hydroxycholesterol protects host against Zika virus infection and its associated microcephaly in a mouse model C Li, YQ Deng, S Wang, F Ma, R Aliyari, XY Huang, NN Zhang, ... Immunity 46 (3), 446-456, 2017 | 325 | 2017 |
Maternal embryonic leucine zipper kinase is a key regulator of the proliferation of malignant brain tumors, including brain tumor stem cells I Nakano, M Masterman‐Smith, K Saigusa, AA Paucar, S Horvath, ... Journal of neuroscience research 86 (1), 48-60, 2007 | 176 | 2007 |
Identification of neural oscillations and epileptiform changes in human brain organoids RA Samarasinghe, OA Miranda, JE Buth, S Mitchell, I Ferando, ... Nature neuroscience 24 (10), 1488-1500, 2021 | 162 | 2021 |
Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production MP Lun, MB Johnson, KG Broadbelt, M Watanabe, Y Kang, KF Chau, ... Journal of Neuroscience 35 (12), 4903-4916, 2015 | 151 | 2015 |
BMP4 sufficiency to induce choroid plexus epithelial fate from embryonic stem cell-derived neuroepithelial progenitors M Watanabe, YJ Kang, LM Davies, S Meghpara, K Lau, CY Chung, ... Journal of Neuroscience 32 (45), 15934-15945, 2012 | 82 | 2012 |
The Fbw7 Tumor Suppressor Regulates Nuclear Factor E2-related Factor 1 Transcription Factor Turnover through Proteasome-mediated Proteolysis M Biswas, D Phan, M Watanabe, JY Chan Journal of Biological Chemistry 286 (45), 39282-39289, 2011 | 80 | 2011 |
Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway I Nakano, K Joshi, K Visnyei, B Hu, M Watanabe, D Lam, E Wexler, ... Neuro-oncology 13 (6), 622-634, 2011 | 77 | 2011 |
Mapping the ethical issues of brain organoid research and application T Sawai, Y Hayashi, T Niikawa, J Shepherd, E Thomas, TL Lee, A Erler, ... AJOB neuroscience 13 (2), 81-94, 2022 | 69 | 2022 |
TGFβ superfamily signaling regulates the state of human stem cell pluripotency and capacity to create well-structured telencephalic organoids M Watanabe, JE Buth, JR Haney, N Vishlaghi, F Turcios, LS Elahi, W Gu, ... Stem Cell Reports 17 (10), 2220-2238, 2022 | 15 | 2022 |
BMP4 acts as a dorsal telencephalic morphogen in a mouse embryonic stem cell culture system M Watanabe, ES Fung, FB Chan, JS Wong, M Coutts, ES Monuki Biology open 5 (12), 1834-1843, 2016 | 9 | 2016 |
TGFβ superfamily signaling regulates the state of human stem cell pluripotency and competency to create telencephalic organoids M Watanabe, JR Haney, N Vishlaghi, F Turcios, JE Buth, W Gu, AJ Collier, ... bioRxiv, 2019.12. 13.875773, 2019 | 8 | 2019 |
Restoration of the defect in radial glial fiber migration and cortical plate organization in a brain organoid model of Fukuyama muscular dystrophy M Taniguchi-Ikeda, M Koyanagi-Aoi, T Maruyama, T Takaori, A Hosoya, ... IScience 24 (10), 2021 | 5 | 2021 |
Brain organoid-on-a-chip to create multiple domains in forebrain organoids YC Tsai, H Ozaki, A Morikawa, K Shiraiwa, AP Pin, AG Salem, ... bioRxiv, 2023.09. 18.558278, 2023 | 2 | 2023 |
Generation of choroid plexus epithelial cells from human embryonic stem cells ES Monuki, M Watanabe US Patent 8,748,176, 2014 | 1 | 2014 |
Brain organoids: New models to study neural development and disease M Watanabe, J Buth, N Vishlaghi, F Turcios, R Samarasinghe, B Novitch APS March Meeting Abstracts 2023, A13. 002, 2023 | | 2023 |
Spatially Heterogeneous Choroid Plexus Transcriptomes Encode Positional Identity and Contribute to Regional CSF Production (March, pg 4903, 2015) MP Lun, MB Johnson, KG Broadbelt, M Watanabe, Y Kang, KF Chau, ... JOURNAL OF NEUROSCIENCE 35 (22), 8686-8686, 2015 | | 2015 |
Bmp4 as a Classic Morphogen for Deriving Dorsal Telencephalic Midline Fates from Embryonic Stem Cells M Watanabe University of California, Irvine, 2013 | | 2013 |
Embryonic Stem Cell-Derived Choroid Plexus Epithelial Cells: A Potential Therapy for Alzheimer's Disease E Monuki, M Watanabe, L Davies, CY Chung, J Kathiriya JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY 70 (6), 517-517, 2011 | | 2011 |
Restoration of Alpha Dystroglycan Glycosylation in Disease Models of Fukuyama Muscular Dystrophy M Taniguchi-Ikeda, M Koyanagi-Aoi, T Maruyama, T Takaori, A Hosoya, ... | | |