| Human embryonic stem cell-derived test systems for developmental neurotoxicity: a transcriptomics approach AK Krug, R Kolde, JA Gaspar, E Rempel, NV Balmer, K Meganathan, ... Archives of toxicology 87, 123-143, 2013 | 252 | 2013 |
| Integration of light and metabolic signals for stem cell activation at the shoot apical meristem A Pfeiffer, D Janocha, Y Dong, A Medzihradszky, S Schöne, G Daum, ... elife 5, e17023, 2016 | 190 | 2016 |
| Implementing tumor mutational burden (TMB) analysis in routine diagnostics—a primer for molecular pathologists and clinicians M Allgäuer, J Budczies, P Christopoulos, V Endris, A Lier, E Rempel, ... Translational lung cancer research 7 (6), 703, 2018 | 175 | 2018 |
| Size matters: dissecting key parameters for panel‐based tumor mutational burden analysis I Buchhalter, E Rempel, V Endris, M Allgäuer, O Neumann, AL Volckmar, ... International journal of cancer 144 (4), 848-858, 2019 | 162 | 2019 |
| Toxicogenomics directory of chemically exposed human hepatocytes M Grinberg, RM Stöber, K Edlund, E Rempel, P Godoy, R Reif, A Widera, ... Archives of toxicology 88, 2261-2287, 2014 | 150 | 2014 |
| Optimizing panel-based tumor mutational burden (TMB) measurement J Budczies, M Allgäuer, K Litchfield, E Rempel, P Christopoulos, D Kazdal, ... Annals of Oncology 30 (9), 1496-1506, 2019 | 140 | 2019 |
| Design principles of concentration-dependent transcriptome deviations in drug-exposed differentiating stem cells T Waldmann, E Rempel, NV Balmer, A König, R Kolde, JA Gaspar, ... Chemical research in toxicology 27 (3), 408-420, 2014 | 112 | 2014 |
| Measurement of tumor mutational burden (TMB) in routine molecular diagnostics: in silico and real‐life analysis of three larger gene panels V Endris, I Buchhalter, M Allgäuer, E Rempel, A Lier, AL Volckmar, ... International journal of cancer 144 (9), 2303-2312, 2019 | 109 | 2019 |
| A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors E Rempel, L Hoelting, T Waldmann, NV Balmer, S Schildknecht, ... Archives of toxicology 89, 1599-1618, 2015 | 102 | 2015 |
| Harmonization and standardization of panel-based tumor mutational burden measurement: real-world results and recommendations of the quality in pathology study A Stenzinger, V Endris, J Budczies, S Merkelbach-Bruse, D Kazdal, ... Journal of Thoracic Oncology 15 (7), 1177-1189, 2020 | 101 | 2020 |
| Combined targeted DNA and RNA sequencing of advanced NSCLC in routine molecular diagnostics: analysis of the first 3,000 Heidelberg cases AL Volckmar, J Leichsenring, M Kirchner, P Christopoulos, O Neumann, ... International Journal of Cancer 145 (3), 649-661, 2019 | 100 | 2019 |
| Variant classification in precision oncology J Leichsenring, P Horak, S Kreutzfeldt, C Heining, P Christopoulos, ... International Journal of Cancer 145 (11), 2996-3010, 2019 | 99 | 2019 |
| Spatial and temporal heterogeneity of panel-based tumor mutational burden in pulmonary adenocarcinoma: separating biology from technical artifacts D Kazdal, V Endris, M Allgäuer, M Kriegsmann, J Leichsenring, ... Journal of Thoracic Oncology 14 (11), 1935-1947, 2019 | 90 | 2019 |
| From transient transcriptome responses to disturbed neurodevelopment: role of histone acetylation and methylation as epigenetic switch between reversible and irreversible drug … NV Balmer, S Klima, E Rempel, VN Ivanova, R Kolde, MK Weng, ... Archives of toxicology 88, 1451-1468, 2014 | 80 | 2014 |
| Motor neurons control blood vessel patterning in the developing spinal cord P Himmels, I Paredes, H Adler, A Karakatsani, R Luck, HH Marti, ... Nature communications 8 (1), 14583, 2017 | 72 | 2017 |
| Glycerol-3-phosphate acyltransferase 1 promotes tumor cell migration and poor survival in ovarian carcinoma R Marchan, B Büttner, J Lambert, K Edlund, I Glaeser, M Blaszkewicz, ... Cancer research 77 (17), 4589-4601, 2017 | 67 | 2017 |
| Definition of transcriptome-based indices for quantitative characterization of chemically disturbed stem cell development: introduction of the STOP-Tox ukn and STOP-Tox ukk tests V Shinde, L Hoelting, SP Srinivasan, J Meisig, K Meganathan, S Jagtap, ... Archives of toxicology 91, 839-864, 2017 | 61 | 2017 |
| Human pluripotent stem cell based developmental toxicity assays for chemical safety screening and systems biology data generation V Shinde, S Klima, PS Sureshkumar, K Meganathan, S Jagtap, E Rempel, ... JoVE (Journal of Visualized Experiments), e52333, 2015 | 57 | 2015 |
| RNA-based detection of gene fusions in formalin-fixed and paraffin-embedded solid cancer samples M Kirchner, O Neumann, AL Volckmar, F Stögbauer, M Allgäuer, D Kazdal, ... Cancers 11 (9), 1309, 2019 | 48 | 2019 |
| Stem cell transcriptome responses and corresponding biomarkers that indicate the transition from adaptive responses to cytotoxicity T Waldmann, M Grinberg, A Konig, E Rempel, S Schildknecht, M Henry, ... Chemical research in toxicology 30 (4), 905-922, 2017 | 45 | 2017 |
