| Family-wide chemical profiling and structural analysis of PARP and tankyrase inhibitors E Wahlberg, T Karlberg, E Kouznetsova, N Markova, A Macchiarulo, ... Nature biotechnology 30 (3), 283-288, 2012 | 548 | 2012 |
| Structural basis for potency and promiscuity in poly (ADP-ribose) polymerase (PARP) and tankyrase inhibitors AG Thorsell, T Ekblad, T Karlberg, M Löw, AF Pinto, L Trésaugues, ... Journal of medicinal chemistry 60 (4), 1262-1271, 2017 | 305 | 2017 |
| Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism K Thangavelu, CQ Pan, T Karlberg, G Balaji, M Uttamchandani, V Suresh, ... Proceedings of the National Academy of Sciences 109 (20), 7705-7710, 2012 | 245 | 2012 |
| Structural basis for the inhibition mechanism of human cystathionine γ-lyase, an enzyme responsible for the production of H2S Q Sun, R Collins, S Huang, L Holmberg-Schiavone, GS Anand, CH Tan, ... Journal of Biological Chemistry 284 (5), 3076-3085, 2009 | 221 | 2009 |
| PARP-3 is a mono-ADP-ribosylase that activates PARP-1 in the absence of DNA O Loseva, AS Jemth, HE Bryant, H Schüler, L Lehtiö, T Karlberg, ... Journal of Biological Chemistry 285 (11), 8054-8060, 2010 | 202 | 2010 |
| Crystal structures of the ATPase domains of four human Hsp70 isoforms: HSPA1L/Hsp70-hom, HSPA2/Hsp70-2, HSPA6/Hsp70B', and HSPA5/BiP/GRP78 M Wisniewska, T Karlberg, L Lehtiö, I Johansson, T Kotenyova, M Moche, ... PloS one 5 (1), e8625, 2010 | 178 | 2010 |
| Crystal structures of mammalian glutamine synthetases illustrate substrate-induced conformational changes and provide opportunities for drug and herbicide design WW Krajewski, R Collins, L Holmberg-Schiavone, TA Jones, T Karlberg, ... Journal of molecular biology 375 (1), 217-228, 2008 | 172 | 2008 |
| The DEXD/H-box RNA helicase DDX19 is regulated by an α-helical switch R Collins, T Karlberg, L Lehtio, P Schutz, S van den Berg, LG Dahlgren, ... Journal of Biological Chemistry 284 (16), 10296-10300, 2009 | 154 | 2009 |
| Crystal structure of conserved domains 1 and 2 of the human DEAD-box helicase DDX3X in complex with the mononucleotide AMP M Högbom, R Collins, S van den Berg, RM Jenvert, T Karlberg, ... Journal of molecular biology 372 (1), 150-159, 2007 | 154 | 2007 |
| Recognition of mono-ADP-ribosylated ARTD10 substrates by ARTD8 macrodomains AH Forst, T Karlberg, N Herzog, AG Thorsell, A Gross, KLH Feijs, ... Structure 21 (3), 462-475, 2013 | 145 | 2013 |
| Structural basis for the interaction between tankyrase-2 and a potent Wnt-signaling inhibitor T Karlberg, N Markova, I Johansson, M Hammarstrom, P Schutz, J Weigelt, ... Journal of medicinal chemistry 53 (14), 5352-5355, 2010 | 138 | 2010 |
| Comparative structural analysis of human DEAD-box RNA helicases P Schütz, T Karlberg, S van den Berg, R Collins, L Lehtiö, M Högbom, ... PloS one 5 (9), e12791, 2010 | 136 | 2010 |
| Structural basis for inhibitor specificity in human poly (ADP-ribose) polymerase-3 L Lehtio, AS Jemth, R Collins, O Loseva, A Johansson, N Markova, ... Journal of medicinal chemistry 52 (9), 3108-3111, 2009 | 115 | 2009 |
| Crystal structure of the catalytic domain of human PARP2 in complex with PARP inhibitor ABT-888 T Karlberg, M Hammarström, P Schütz, L Svensson, H Schüler Biochemistry 49 (6), 1056-1058, 2010 | 92 | 2010 |
| The structures of frataxin oligomers reveal the mechanism for the delivery and detoxification of iron T Karlberg, U Schagerlöf, O Gakh, S Park, U Ryde, M Lindahl, K Leath, ... Structure 14 (10), 1535-1546, 2006 | 89 | 2006 |
| Structural biology of the writers, readers, and erasers in mono-and poly (ADP-ribose) mediated signaling T Karlberg, MF Langelier, JM Pascal, H Schüler Molecular aspects of medicine 34 (6), 1088-1108, 2013 | 84 | 2013 |
| Structural basis for lack of ADP-ribosyltransferase activity in poly (ADP-ribose) polymerase-13/zinc finger antiviral protein T Karlberg, M Klepsch, AG Thorsell, CD Andersson, A Linusson, ... Journal of Biological Chemistry 290 (12), 7336-7344, 2015 | 82 | 2015 |
| Zinc binding catalytic domain of human tankyrase 1 L Lehtiö, R Collins, S van den Berg, A Johansson, LG Dahlgren, ... Journal of molecular biology 379 (1), 136-145, 2008 | 79 | 2008 |
| Porphyrin binding and distortion and substrate specificity in the ferrochelatase reaction: the role of active site residues T Karlberg, MD Hansson, RK Yengo, R Johansson, HO Thorvaldsen, ... Journal of molecular biology 378 (5), 1074-1083, 2008 | 67 | 2008 |
| Amino Acid Residues His183 and Glu264 in Bacillus subtilis Ferrochelatase Direct and Facilitate the Insertion of Metal Ion into Protoporphyrin IX, MD Hansson, T Karlberg, MA Rahardja, S Al-Karadaghi, M Hansson Biochemistry 46 (1), 87-94, 2007 | 66 | 2007 |
