关注
Laura M. Walker
Laura M. Walker
未知所在单位机构
在 adagiotx.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target
LM Walker, SK Phogat, PY Chan-Hui, D Wagner, P Phung, JL Goss, ...
Science 326 (5950), 285-289, 2009
21092009
Broad neutralization coverage of HIV by multiple highly potent antibodies
LM Walker, M Huber, KJ Doores, E Falkowska, R Pejchal, JP Julien, ...
Nature 477 (7365), 466-470, 2011
17452011
Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9
JS McLellan, M Pancera, C Carrico, J Gorman, JP Julien, R Khayat, ...
Nature 480 (7377), 336-343, 2011
10402011
A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield
R Pejchal, KJ Doores, LM Walker, R Khayat, PS Huang, SK Wang, ...
Science 334 (6059), 1097-1103, 2011
8702011
Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay …
MD Simek, W Rida, FH Priddy, P Pung, E Carrow, DS Laufer, JK Lehrman, ...
Journal of virology 83 (14), 7337-7348, 2009
6822009
Broad neutralization of SARS-related viruses by human monoclonal antibodies
AZ Wec, D Wrapp, AS Herbert, DP Maurer, D Haslwanter, M Sakharkar, ...
Science 369 (6504), 731-736, 2020
5492020
A blueprint for HIV vaccine discovery
DR Burton, R Ahmed, DH Barouch, ST Butera, S Crotty, A Godzik, ...
Cell host & microbe 12 (4), 396-407, 2012
4582012
A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals
LM Walker, MD Simek, F Priddy, JS Gach, D Wagner, MB Zwick, ...
PLoS pathogens 6 (8), e1001028, 2010
4432010
Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans
JP Julien, D Sok, R Khayat, JH Lee, KJ Doores, LM Walker, A Ramos, ...
PLoS pathogens 9 (5), e1003342, 2013
4062013
Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody
CG Rappazzo, LV Tse, CI Kaku, D Wrapp, M Sakharkar, D Huang, ...
Science 371 (6531), 823-829, 2021
2982021
Mechanism of neutralization by the broadly neutralizing HIV-1 monoclonal antibody VRC01
Y Li, S O'Dell, LM Walker, X Wu, J Guenaga, Y Feng, SD Schmidt, ...
Journal of virology 85 (17), 8954-8967, 2011
2852011
Passive immunotherapy of viral infections:'super-antibodies' enter the fray
LM Walker, DR Burton
Nature Reviews Immunology 18 (5), 297-308, 2018
2822018
Rational antibody-based HIV-1 vaccine design: current approaches and future directions
LM Walker, DR Burton
Current opinion in immunology 22 (3), 358-366, 2010
2672010
Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1
R Pejchal, LM Walker, RL Stanfield, SK Phogat, WC Koff, P Poignard, ...
Proceedings of the National Academy of Sciences 107 (25), 11483-11488, 2010
2592010
The effects of somatic hypermutation on neutralization and binding in the PGT121 family of broadly neutralizing HIV antibodies
D Sok, U Laserson, J Laserson, Y Liu, F Vigneault, JP Julien, B Briney, ...
PLoS pathogens 9 (11), e1003754, 2013
2492013
Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak
ZA Bornholdt, HL Turner, CD Murin, W Li, D Sok, CA Souders, AE Piper, ...
Science 351 (6277), 1078-1083, 2016
2322016
Rapid profiling of RSV antibody repertoires from the memory B cells of naturally infected adult donors
MSA Gilman, CA Castellanos, M Chen, JO Ngwuta, E Goodwin, SM Moin, ...
Science immunology 1 (6), eaaj1879, 2016
2152016
Systematic analysis of monoclonal antibodies against Ebola virus GP defines features that contribute to protection
EO Saphire, SL Schendel, ML Fusco, K Gangavarapu, BM Gunn, AZ Wec, ...
Cell 174 (4), 938-952. e13, 2018
1912018
Prolonged evolution of the human B cell response to SARS-CoV-2 infection
M Sakharkar, CG Rappazzo, WF Wieland-Alter, CL Hsieh, D Wrapp, ...
Science immunology 6 (56), eabg6916, 2021
1772021
Antibodies from a human survivor define sites of vulnerability for broad protection against ebolaviruses
AZ Wec, AS Herbert, CD Murin, EK Nyakatura, DM Abelson, JM Fels, ...
Cell 169 (5), 878-890. e15, 2017
1582017
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