Broad and potent neutralizing antibodies from an African donor reveal a new HIV-1 vaccine target LM Walker, SK Phogat, PY Chan-Hui, D Wagner, P Phung, JL Goss, ... Science 326 (5950), 285-289, 2009 | 2109 | 2009 |
Broad neutralization coverage of HIV by multiple highly potent antibodies LM Walker, M Huber, KJ Doores, E Falkowska, R Pejchal, JP Julien, ... Nature 477 (7365), 466-470, 2011 | 1745 | 2011 |
Structure of HIV-1 gp120 V1/V2 domain with broadly neutralizing antibody PG9 JS McLellan, M Pancera, C Carrico, J Gorman, JP Julien, R Khayat, ... Nature 480 (7377), 336-343, 2011 | 1040 | 2011 |
A potent and broad neutralizing antibody recognizes and penetrates the HIV glycan shield R Pejchal, KJ Doores, LM Walker, R Khayat, PS Huang, SK Wang, ... Science 334 (6059), 1097-1103, 2011 | 870 | 2011 |
Human immunodeficiency virus type 1 elite neutralizers: individuals with broad and potent neutralizing activity identified by using a high-throughput neutralization assay … MD Simek, W Rida, FH Priddy, P Pung, E Carrow, DS Laufer, JK Lehrman, ... Journal of virology 83 (14), 7337-7348, 2009 | 682 | 2009 |
Broad neutralization of SARS-related viruses by human monoclonal antibodies AZ Wec, D Wrapp, AS Herbert, DP Maurer, D Haslwanter, M Sakharkar, ... Science 369 (6504), 731-736, 2020 | 549 | 2020 |
A blueprint for HIV vaccine discovery DR Burton, R Ahmed, DH Barouch, ST Butera, S Crotty, A Godzik, ... Cell host & microbe 12 (4), 396-407, 2012 | 458 | 2012 |
A limited number of antibody specificities mediate broad and potent serum neutralization in selected HIV-1 infected individuals LM Walker, MD Simek, F Priddy, JS Gach, D Wagner, MB Zwick, ... PLoS pathogens 6 (8), e1001028, 2010 | 443 | 2010 |
Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans JP Julien, D Sok, R Khayat, JH Lee, KJ Doores, LM Walker, A Ramos, ... PLoS pathogens 9 (5), e1003342, 2013 | 406 | 2013 |
Broad and potent activity against SARS-like viruses by an engineered human monoclonal antibody CG Rappazzo, LV Tse, CI Kaku, D Wrapp, M Sakharkar, D Huang, ... Science 371 (6531), 823-829, 2021 | 298 | 2021 |
Mechanism of neutralization by the broadly neutralizing HIV-1 monoclonal antibody VRC01 Y Li, S O'Dell, LM Walker, X Wu, J Guenaga, Y Feng, SD Schmidt, ... Journal of virology 85 (17), 8954-8967, 2011 | 285 | 2011 |
Passive immunotherapy of viral infections:'super-antibodies' enter the fray LM Walker, DR Burton Nature Reviews Immunology 18 (5), 297-308, 2018 | 282 | 2018 |
Rational antibody-based HIV-1 vaccine design: current approaches and future directions LM Walker, DR Burton Current opinion in immunology 22 (3), 358-366, 2010 | 267 | 2010 |
Structure and function of broadly reactive antibody PG16 reveal an H3 subdomain that mediates potent neutralization of HIV-1 R Pejchal, LM Walker, RL Stanfield, SK Phogat, WC Koff, P Poignard, ... Proceedings of the National Academy of Sciences 107 (25), 11483-11488, 2010 | 259 | 2010 |
The effects of somatic hypermutation on neutralization and binding in the PGT121 family of broadly neutralizing HIV antibodies D Sok, U Laserson, J Laserson, Y Liu, F Vigneault, JP Julien, B Briney, ... PLoS pathogens 9 (11), e1003754, 2013 | 249 | 2013 |
Isolation of potent neutralizing antibodies from a survivor of the 2014 Ebola virus outbreak ZA Bornholdt, HL Turner, CD Murin, W Li, D Sok, CA Souders, AE Piper, ... Science 351 (6277), 1078-1083, 2016 | 232 | 2016 |
Rapid profiling of RSV antibody repertoires from the memory B cells of naturally infected adult donors MSA Gilman, CA Castellanos, M Chen, JO Ngwuta, E Goodwin, SM Moin, ... Science immunology 1 (6), eaaj1879, 2016 | 215 | 2016 |
Systematic analysis of monoclonal antibodies against Ebola virus GP defines features that contribute to protection EO Saphire, SL Schendel, ML Fusco, K Gangavarapu, BM Gunn, AZ Wec, ... Cell 174 (4), 938-952. e13, 2018 | 191 | 2018 |
Prolonged evolution of the human B cell response to SARS-CoV-2 infection M Sakharkar, CG Rappazzo, WF Wieland-Alter, CL Hsieh, D Wrapp, ... Science immunology 6 (56), eabg6916, 2021 | 177 | 2021 |
Antibodies from a human survivor define sites of vulnerability for broad protection against ebolaviruses AZ Wec, AS Herbert, CD Murin, EK Nyakatura, DM Abelson, JM Fels, ... Cell 169 (5), 878-890. e15, 2017 | 158 | 2017 |