Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer YP Kang, L Torrente, A Falzone, CM Elkins, M Liu, JM Asara, CC Dibble, ... Elife 8, e45572, 2019 | 102 | 2019 |
Targeting NRF2 and its downstream processes: opportunities and challenges L Torrente, GM DeNicola Annual review of pharmacology and toxicology 62 (1), 279-300, 2022 | 99 | 2022 |
Crosstalk between NRF2 and HIPK2 shapes cytoprotective responses L Torrente, C Sanchez, R Moreno, S Chowdhry, P Cabello, K Isono, ... Oncogene 36 (44), 6204-6212, 2017 | 94 | 2017 |
Heat shock factor 1 is a substrate for p38 mitogen-activated protein kinases S Dayalan Naidu, C Sutherland, Y Zhang, A Risco, L de la Vega, ... Molecular and cellular biology 36 (18), 2403-2417, 2016 | 84 | 2016 |
Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone L Torrente, N Prieto-Farigua, A Falzone, CM Elkins, DA Boothman, ... Redox biology 30, 101440, 2020 | 38 | 2020 |
High NRF2 levels correlate with poor prognosis in colorectal cancer patients and with sensitivity to the kinase inhibitor AT9283 in vitro L Torrente, G Maan, A Oumkaltoum Rezig, J Quinn, A Jackson, A Grilli, ... Biomolecules 10 (10), 1365, 2020 | 35 | 2020 |
Oxidation state-specific fluorescent copper sensors reveal oncogene-driven redox changes that regulate labile copper (II) pools AT Pezacki, CD Matier, X Gu, E Kummelstedt, SE Bond, L Torrente, ... Proceedings of the National Academy of Sciences 119 (43), e2202736119, 2022 | 33 | 2022 |
Dynamics and dispensability of variant-specific histone H1 Lys-26/Ser-27 and Thr-165 post-translational modifications JM Terme, L Millán-Ariño, R Mayor, N Luque, A Izquierdo-Bouldstridge, ... FEBS letters 588 (14), 2353-2362, 2014 | 26 | 2014 |
GAPDH redox redux—rewiring pentose phosphate flux L Torrente, GM DeNicola Nature Metabolism 5 (4), 538-539, 2023 | 5 | 2023 |
Stressing out PanIN: NRF2 pushes over the edge L Torrente, GM DeNicola Cancer Cell 32 (6), 723-725, 2017 | 5 | 2017 |
Imaging the master regulator of the antioxidant response in non-small cell lung cancer with positron emission tomography HE Greenwood, RS Edwards, WE Tyrrell, AR Barber, F Baark, M Tanc, ... bioRxiv, 2023 | 2 | 2023 |
Correction: Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer YP Kang, L Torrente, A Falzone, CM Elkins, M Liu, JM Asara, CC Dibble, ... Elife 8, e52671, 2019 | 1 | 2019 |
A tandem activity-based sensing and labeling strategy reveals antioxidant response element regulation of labile iron pools AT Pezacki, RL Gonciarz, T Okamura, CD Matier, L Torrente, K Cheng, ... Proceedings of the National Academy of Sciences 121 (28), e2401579121, 2024 | | 2024 |
An Activity-Based Sensing Approach to Multiplex Mapping of Labile Copper Pools by Stimulated Raman Scattering Y Jiang, E El Khoury, AT Pezacki, N Qian, M Oi, L Torrente, S Miller, ... | | 2024 |
The kinase inhibitor AT9283 selectively kills colorectal cancer cells with hyperactive NRF2 L Torrente, G Maan, L Casares, A Jackson, T Honda, G Wells, E Kulesskiy, ... bioRxiv, 812909, 2019 | | 2019 |