| 5-substituted indazoles as kinase inhibitors I Akritopoulou-Zanze, BD Wakefield, H Mack, SC Turner, AF Gasiecki, ... US Patent 8,648,069, 2014 | 223 | 2014 |
| Novel therapeutic compounds EC Breinlinger, KP Cusack, AD Hobson, B Li, TD Gordon, RH Stoffel, ... US Patent App. 12/218,364, 2009 | 122 | 2009 |
| Oxadiazole compounds AD Hobson, SR Fix-Stenzel, KP Cusack, EC Breinlinger, GK Ansell, ... US Patent 7,834,039, 2010 | 119 | 2010 |
| Tricyclic covalent inhibitors selectively target Jak3 through an active site thiol ER Goedken, MA Argiriadi, DL Banach, BA Fiamengo, SE Foley, ... Journal of Biological Chemistry 290 (8), 4573-4589, 2015 | 100 | 2015 |
| Stereoselective construction of quaternary centers at ambient temperature by the highly stereocontrolled migration of groups containing sp-, sp2-, and sp3-hybridized carbon atoms CM Marson, AJ Walker, J Pickering, AD Hobson, R Wrigglesworth, ... The Journal of Organic Chemistry 58 (22), 5944-5951, 1993 | 94 | 1993 |
| Discovery of A-971432, An Orally Bioavailable Selective Sphingosine-1-Phosphate Receptor 5 (S1P5) Agonist for the Potential Treatment of Neurodegenerative … AD Hobson, CM Harris, EL van der Kam, SC Turner, A Abibi, AL Aguirre, ... Journal of medicinal chemistry 58 (23), 9154-9170, 2015 | 60 | 2015 |
| Covalent binders in drug discovery A Vasudevan, MA Argiriadi, A Baranczak, MM Friedman, J Gavrilyuk, ... Progress in medicinal chemistry 58, 1-62, 2019 | 43 | 2019 |
| Highly diastereoselective 1, 3-dipolar cycloaddition reactions of trans-2-methylene-1, 3-dithiolane 1, 3-dioxide with 3-oxidopyridinium and 3-oxidopyrylium betaines: a route to … VK Aggarwal, RS Grainger, GK Newton, PL Spargo, AD Hobson, ... Organic & biomolecular chemistry 1 (11), 1884-1893, 2003 | 42 | 2003 |
| Novel tricyclic compounds N Wishart, DF Bonafoux, KE Frank, AD Hobson, DB Konopacki, ... US Patent App. 13/623,393, 2013 | 40 | 2013 |
| Aminopyrrolidines as chemokine receptor antagonists DM George, RW Dixon, M Friedman, AD Hobson, B Li, L Wang, X Wu, ... US Patent 8,754,107, 2014 | 32 | 2014 |
| Stereocontrolled syntheses of hydroxylated tricyclic systems by a new annulation of 2-cyclohexen-1-one CM Marson, DWM Benzies, AD Hobson Tetrahedron 47 (29), 5491-5506, 1991 | 30 | 1991 |
| Pushing the envelope: Advancement of ADCs outside of oncology MJ McPherson, AD Hobson Antibody-Drug Conjugates: Methods and Protocols, 23-36, 2020 | 28 | 2020 |
| Design and development of glucocorticoid receptor modulators as immunology antibody–drug conjugate payloads AD Hobson, MJ McPherson, W Waegell, CA Goess, RH Stoffel, X Li, ... Journal of Medicinal Chemistry 65 (6), 4500-4533, 2022 | 27 | 2022 |
| Identification of selective dual ROCK1 and ROCK2 inhibitors using structure-based drug design AD Hobson, RA Judge, AL Aguirre, BS Brown, Y Cui, P Ding, ... Journal of medicinal chemistry 61 (24), 11074-11100, 2018 | 25 | 2018 |
| Discovery of ABBV-3373, an anti-TNF glucocorticoid receptor modulator immunology antibody drug conjugate AD Hobson, MJ McPherson, ME Hayes, C Goess, X Li, J Zhou, Z Wang, ... Journal of medicinal chemistry 65 (23), 15893-15934, 2022 | 24 | 2022 |
| Nuclear Hormone Receptor Modulators KP Cusack, TD Gordon, DC Ihle, ME Hayes, EC Breinlinger, AM Ericsson, ... US Patent App. 13/420,957, 2012 | 24 | 2012 |
| Sphingosine-1-phosphate receptor agonist and antagonist compounds GA Wallace, EC Breinlinger, KP Cusack, SR Fix-Stenzel, TD Gordon, ... US Patent 8,217,027, 2012 | 21 | 2012 |
| Development of orally efficacious allosteric inhibitors of TNFα via fragment-based drug design JD Dietrich, KL Longenecker, NS Wilson, C Goess, SC Panchal, ... Journal of Medicinal Chemistry 64 (1), 417-429, 2020 | 19 | 2020 |
| Glucocorticoid receptor agonist and immunoconjugates thereof MJ McPherson, AD Hobson, ME Hayes, CC Marvin, D Schmidt, ... US Patent 10,668,167, 2020 | 15 | 2020 |
| POS0365 anti-TNF glucocorticoid receptor modulator antibody drug conjugate for the treatment of autoimmune diseases B Stoffel, M McPherson, A Hernandez, C Goess, S Mathieu, W Waegell, ... Annals of the Rheumatic Diseases 80 (Suppl 1), 412-413, 2021 | 13 | 2021 |
