| Integrating evolutionary dynamics into treatment of metastatic castrate-resistant prostate cancer J Zhang, JJ Cunningham, JS Brown, RA Gatenby Nature communications 8 (1), 1816, 2017 | 492 | 2017 |
| Darwinian dynamics of intratumoral heterogeneity: not solely random mutations but also variable environmental selection forces MC Lloyd, JJ Cunningham, MM Bui, RJ Gillies, JS Brown, RA Gatenby Cancer research 76 (11), 3136-3144, 2016 | 249 | 2016 |
| Optimal control to develop therapeutic strategies for metastatic castrate resistant prostate cancer JJ Cunningham, JS Brown, RA Gatenby, K Staňková Journal of theoretical biology 459, 67-78, 2018 | 112 | 2018 |
| Reduction of metastasis using a non-volatile buffer A Ibrahim Hashim, HH Cornnell, ML Coelho Ribeiro, D Abrahams, ... Clinical & experimental metastasis 28, 841-849, 2011 | 111 | 2011 |
| Evolutionary triage governs fitness in driver and passenger mutations and suggests targeting never mutations RA Gatenby, JJ Cunningham, JS Brown Nature communications 5 (1), 5499, 2014 | 89 | 2014 |
| Evolutionary dynamics in cancer therapy JJ Cunningham, RA Gatenby, JS Brown Molecular pharmaceutics 8 (6), 2094-2100, 2011 | 88 | 2011 |
| Spatial vs. non-spatial eco-evolutionary dynamics in a tumor growth model L You, JS Brown, F Thuijsman, JJ Cunningham, RA Gatenby, J Zhang, ... Journal of theoretical biology 435, 78-97, 2017 | 65 | 2017 |
| Optimal control to reach eco-evolutionary stability in metastatic castrate-resistant prostate cancer J Cunningham, F Thuijsman, R Peeters, Y Viossat, J Brown, R Gatenby, ... Plos one 15 (12), e0243386, 2020 | 52 | 2020 |
| Evolution-based mathematical models significantly prolong response to abiraterone in metastatic castrate-resistant prostate cancer and identify strategies to further improve … J Zhang, J Cunningham, J Brown, R Gatenby Elife 11, e76284, 2022 | 50 | 2022 |
| A call for integrated metastatic management JJ Cunningham Nature ecology & evolution 3 (7), 996-998, 2019 | 41 | 2019 |
| Frequency-dependent interactions determine outcome of competition between two breast cancer cell lines AR Freischel, M Damaghi, JJ Cunningham, A Ibrahim-Hashim, RJ Gillies, ... Scientific reports 11 (1), 4908, 2021 | 38 | 2021 |
| Aggregation effects and population-based dynamics as a source of therapy resistance in cancer JS Brown, JJ Cunningham, RA Gatenby IEEE Transactions on Biomedical Engineering 64 (3), 512-518, 2016 | 35 | 2016 |
| Intracellular electric field and pH optimize protein localization and movement J Cunningham, V Estrella, M Lloyd, R Gillies, BR Frieden, R Gatenby PloS one 7 (5), e36894, 2012 | 34 | 2012 |
| The multiple facets of Peto's paradox: a life-history model for the evolution of cancer suppression JS Brown, JJ Cunningham, RA Gatenby Philosophical Transactions of the Royal Society B: Biological Sciences 370 …, 2015 | 31 | 2015 |
| Divergent and convergent evolution in metastases suggest treatment strategies based on specific metastatic sites JJ Cunningham, JS Brown, TL Vincent, RA Gatenby Evolution, medicine, and public health 2015 (1), 76-87, 2015 | 29 | 2015 |
| Cytoplasmic convection currents and intracellular temperature gradients R Howard, A Scheiner, J Cunningham, R Gatenby PLoS Computational Biology 15 (11), e1007372, 2019 | 22 | 2019 |
| Coupled source-sink habitats produce spatial and temporal variation of cancer cell molecular properties as an alternative to branched clonal evolution and stem cell paradigms JJ Cunningham, A Bukkuri, JS Brown, RJ Gillies, RA Gatenby Frontiers in Ecology and Evolution 9, 676071, 2021 | 14 | 2021 |
| A phase 1b adaptive androgen deprivation therapy trial in metastatic castration sensitive prostate cancer J Zhang, J Gallaher, JJ Cunningham, JW Choi, F Ionescu, MS Chatwal, ... Cancers 14 (21), 5225, 2022 | 9 | 2022 |
| Response to mistry J Zhang, JJ Cunningham, JS Brown, RA Gatenby Nature communications 12 (1), 329, 2021 | 9 | 2021 |
| Resistance is not the end: lessons from pest management CJ Whelan, JJ Cunningham Cancer Control 27 (1), 1073274820922543, 2020 | 7 | 2020 |
