Comprehensive genomic characterization of head and neck squamous cell carcinomas Cancer Genome Atlas Network Nature 517 (7536), 576, 2015 | 3248 | 2015 |
Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1 N Agrawal, MJ Frederick, CR Pickering, C Bettegowda, K Chang, RJ Li, ... Science 333 (6046), 1154-1157, 2011 | 2020 | 2011 |
Mutational landscape of aggressive cutaneous squamous cell carcinoma CR Pickering, JH Zhou, JJ Lee, JA Drummond, SA Peng, RE Saade, ... Clinical cancer research 20 (24), 6582-6592, 2014 | 676 | 2014 |
Integrative genomic characterization of oral squamous cell carcinoma identifies frequent somatic drivers CR Pickering, J Zhang, SY Yoo, L Bengtsson, S Moorthy, DM Neskey, ... Cancer discovery 3 (7), 770-781, 2013 | 586 | 2013 |
Detection of somatic mutations and HPV in the saliva and plasma of patients with head and neck squamous cell carcinomas Y Wang, S Springer, CL Mulvey, N Silliman, J Schaefer, M Sausen, ... Science translational medicine 7 (293), 293ra104-293ra104, 2015 | 543 | 2015 |
Characterization of HPV and host genome interactions in primary head and neck cancers M Parfenov, CS Pedamallu, N Gehlenborg, SS Freeman, L Danilova, ... Proceedings of the National Academy of Sciences 111 (43), 15544-15549, 2014 | 422 | 2014 |
The integrated genomic landscape of thymic epithelial tumors M Radovich, CR Pickering, I Felau, G Ha, H Zhang, H Jo, KA Hoadley, ... Cancer cell 33 (2), 244-258. e10, 2018 | 315 | 2018 |
Loss of p53 drives neuron reprogramming in head and neck cancer M Amit, H Takahashi, MP Dragomir, A Lindemann, FO Gleber-Netto, ... Nature 578 (7795), 449-454, 2020 | 293 | 2020 |
Genomic, pathway network, and immunologic features distinguishing squamous carcinomas JD Campbell, C Yau, R Bowlby, Y Liu, K Brennan, H Fan, AM Taylor, ... Cell reports 23 (1), 194-212. e6, 2018 | 293 | 2018 |
Assembly and initial characterization of a panel of 85 genomically validated cell lines from diverse head and neck tumor sites M Zhao, D Sano, CR Pickering, SA Jasser, YC Henderson, GL Clayman, ... Clinical cancer research 17 (23), 7248-7264, 2011 | 289 | 2011 |
High intratumor genetic heterogeneity is related to worse outcome in patients with head and neck squamous cell carcinoma EA Mroz, AD Tward, CR Pickering, JN Myers, RL Ferris, JW Rocco Cancer 119 (16), 3034-3042, 2013 | 233 | 2013 |
Automated hypothesis generation based on mining scientific literature S Spangler, AD Wilkins, BJ Bachman, M Nagarajan, T Dayaram, P Haas, ... Proceedings of the 20th ACM SIGKDD international conference on Knowledge …, 2014 | 177 | 2014 |
Key tumor suppressor genes inactivated by “greater promoter” methylation and somatic mutations in head and neck cancer R Guerrero-Preston, C Michailidi, L Marchionni, CR Pickering, ... Epigenetics 9 (7), 1031-1046, 2014 | 171 | 2014 |
Evolutionary action score of TP53 identifies high-risk mutations associated with decreased survival and increased distant metastases in head and neck cancer DM Neskey, AA Osman, TJ Ow, P Katsonis, T McDonald, SC Hicks, ... Cancer research 75 (7), 1527-1536, 2015 | 168 | 2015 |
Squamous cell carcinoma of the oral tongue in young non-smokers is genomically similar to tumors in older smokers CR Pickering, J Zhang, DM Neskey, M Zhao, SA Jasser, J Wang, A Ward, ... Clinical Cancer Research 20 (14), 3842-3848, 2014 | 160 | 2014 |
Glucose, not glutamine, is the dominant energy source required for proliferation and survival of head and neck squamous carcinoma cells VC Sandulache, TJ Ow, CR Pickering, MJ Frederick, G Zhou, I Fokt, ... Cancer 117 (13), 2926-2938, 2011 | 153 | 2011 |
A pan-cancer analysis reveals high-frequency genetic alterations in mediators of signaling by the TGF-β superfamily A Korkut, S Zaidi, RS Kanchi, S Rao, NR Gough, A Schultz, X Li, ... Cell systems 7 (4), 422-437. e7, 2018 | 145 | 2018 |
Cross-species identification of genomic drivers of squamous cell carcinoma development across preneoplastic intermediates V Chitsazzadeh, C Coarfa, JA Drummond, T Nguyen, A Joseph, ... Nature communications 7 (1), 12601, 2016 | 137 | 2016 |
Chk1/2 inhibition overcomes the cisplatin resistance of head and neck cancer cells secondary to the loss of functional p53 MA Gadhikar, MR Sciuto, MVO Alves, CR Pickering, AA Osman, ... Molecular cancer therapeutics 12 (9), 1860-1873, 2013 | 125 | 2013 |
Disruptive TP53 Mutation Is Associated with Aggressive Disease Characteristics in an Orthotopic Murine Model of Oral Tongue Cancer D Sano, TX Xie, TJ Ow, M Zhao, CR Pickering, G Zhou, VC Sandulache, ... Clinical cancer research 17 (21), 6658-6670, 2011 | 122 | 2011 |