An environmental bacterial taxon with a large and distinct metabolic repertoire MC Wilson, T Mori, C Rückert, AR Uria, MJ Helf, K Takada, C Gernert, ... Nature 506 (7486), 58-62, 2014 | 629 | 2014 |
Metagenome mining reveals polytheonamides as posttranslationally modified ribosomal peptides MF Freeman, C Gurgui, MJ Helf, BI Morinaka, AR Uria, NJ Oldham, ... Science 338 (6105), 387-390, 2012 | 388 | 2012 |
Radical S‐Adenosyl Methionine Epimerases: Regioselective Introduction of Diverse D‐Amino Acid Patterns into Peptide Natural Products BI Morinaka, AL Vagstad, MJ Helf, M Gugger, C Kegler, MF Freeman, ... Angewandte Chemie International Edition 53 (32), 8503-8507, 2014 | 132* | 2014 |
Seven enzymes create extraordinary molecular complexity in an uncultivated bacterium MF Freeman, MJ Helf, A Bhushan, BI Morinaka, J Piel Nature chemistry 9 (4), 387-395, 2017 | 125 | 2017 |
Autocatalytic backbone N-methylation in a family of ribosomal peptide natural products NS Van Der Velden, N Kälin, MJ Helf, J Piel, MF Freeman, M Künzler Nature chemical biology 13 (8), 833-835, 2017 | 123 | 2017 |
Natural noncanonical protein splicing yields products with diverse β-amino acid residues BI Morinaka, E Lakis, M Verest, MJ Helf, T Scalvenzi, AL Vagstad, J Sims, ... Science 359 (6377), 779-782, 2018 | 102 | 2018 |
A practical guide to metabolomics software development HY Chang, SM Colby, X Du, JD Gomez, MJ Helf, K Kechris, ... Analytical chemistry 93 (4), 1912-1923, 2021 | 46 | 2021 |
Comparative metabolomics with Metaboseek reveals functions of a conserved fat metabolism pathway in C. elegans MJ Helf, BW Fox, AB Artyukhin, YK Zhang, FC Schroeder Nature Communications 13 (1), 782, 2022 | 31 | 2022 |
Deep interrogation of metabolism using a pathway-targeted click-chemistry approach JS Hoki, HH Le, KE Mellott, YK Zhang, BW Fox, PR Rodrigues, Y Yu, ... Journal of the American Chemical Society 142 (43), 18449-18459, 2020 | 21 | 2020 |
Modular metabolite assembly in Caenorhabditis elegans depends on carboxylesterases and formation of lysosome-related organelles HH Le, CJJ Wrobel, SM Cohen, J Yu, H Park, MJ Helf, BJ Curtis, ... Elife 9, e61886, 2020 | 18 | 2020 |
Enzyme from an uncultivated sponge bacterium catalyzes s‐methylation in a ribosomal peptide MJ Helf, A Jud, J Piel ChemBioChem 18 (5), 444-450, 2017 | 17 | 2017 |
Investigations into PoyH, a promiscuous protease from polytheonamide biosynthesis MJ Helf, MF Freeman, J Piel Journal of Industrial Microbiology and Biotechnology 46 (3-4), 551-563, 2019 | 14 | 2019 |
Modular metabolite assembly in C. elegans lysosome-related organelles HH Le, CJJ Wrobel, SM Cohen, J Yu, H Park, MJ Helf, BJ Curtis, ... BioRxiv, in press.[Europe PMC free article][Abstract][Google Scholar], 2020 | 2 | 2020 |
Biosynthetic gene cluster for the production of peptide/protein analogues J Piel, C Gurgui, MF Freeman, AR Uria, MJ Helf US Patent App. 14/342,539, 2014 | 2 | 2014 |
Evolutionarily related host and microbial pathways regulate fat desaturation in C. elegans BW Fox, MJ Helf, RN Burkhardt, AB Artyukhin, BJ Curtis, DF Palomino, ... Nature Communications 15 (1), 1520, 2024 | | 2024 |
Evolutionarily related host and microbial pathways regulate fat desaturation BW Fox, MJ Helf, RN Burkhardt, AB Artyukhin, BJ Curtis, DF Palomino, ... bioRxiv, 2023 | | 2023 |
Exploring the proteusin family of unusual ribosomal peptide natural products MJ Helf ETH Zurich, 2015 | | 2015 |