β-Sitosterol targets Trx/Trx1 reductase to induce apoptosis in A549 cells via ROS mediated mitochondrial dysregulation and p53 activation T Rajavel, P Packiyaraj, V Suryanarayanan, SK Singh, K Ruckmani, ... Scientific Reports 8 (1), 2071, 2018 | 96 | 2018 |
Anti-amyloidogenic and anti-apoptotic effect of α-bisabolol against Aβ induced neurotoxicity in PC12 cells B Shanmuganathan, V Suryanarayanan, S Sathya, M Narenkumar, ... European journal of medicinal chemistry 143, 1196-1207, 2018 | 50 | 2018 |
Vitexin inhibits Aβ25-35 induced toxicity in Neuro-2a cells by augmenting Nrf-2/HO-1 dependent antioxidant pathway and regulating lipid homeostasis by the activation of LXR-α DS Malar, V Suryanarayanan, MI Prasanth, SK Singh, K Balamurugan, ... Toxicology in Vitro 50, 160-171, 2018 | 47 | 2018 |
Assessment of dual inhibition property of newly discovered inhibitors against PCAF and GCN5 through in silico screening, molecular dynamics simulation and DFT approach V Suryanarayanan, SK Singh Journal of Receptors and Signal Transduction 35 (5), 370-380, 2015 | 45 | 2015 |
Shape and pharmacophore-based virtual screening to identify potential cytochrome P450 sterol 14α-demethylase inhibitors KK Reddy, SK Singh, SK Tripathi, C Selvaraj, V Suryanarayanan Journal of Receptors and Signal Transduction 33 (4), 234-243, 2013 | 41 | 2013 |
Molecular docking and structure-based virtual screening studies of potential drug target, CAAX prenyl proteases, of Leishmania donovani S Singh, S Vijaya Prabhu, V Suryanarayanan, R Bhardwaj, SK Singh, ... Journal of Biomolecular Structure and Dynamics 34 (11), 2367-2386, 2016 | 34 | 2016 |
Daucosterol disturbs redox homeostasis and elicits oxidative-stress mediated apoptosis in A549 cells via targeting thioredoxin reductase by a p53 dependent mechanism T Rajavel, GB Priya, V Suryanarayanan, SK Singh, KP Devi European Journal of Pharmacology 855, 112-123, 2019 | 20 | 2019 |
A three-dimensional chemical phase pharmacophore mapping, QSAR modelling and electronic feature analysis of benzofuran salicylic acid derivatives as LYP inhibitors V Suryanarayanan, S Kumar Singh, S Kumar Tripathi, C Selvaraj, ... SAR and QSAR in Environmental Research 24 (12), 1025-1040, 2013 | 20 | 2013 |
α-bisabolol β-D-fucopyranoside as a potential modulator of β-amyloid peptide induced neurotoxicity: An in vitro & in silico study M Jeyakumar, S Sathya, S Gandhi, P Tharra, V Suryanarayanan, ... Bioorganic Chemistry 88, 102935, 2019 | 16 | 2019 |
Atom-based 3D QSAR studies on novel N-β-d-xylosylindole derivatives as SGLT2 inhibitors V Suryanarayanan, A Sudha, S Rajamanikandan, R Vanajothi, ... Medicinal Chemistry Research 22, 615-624, 2013 | 16 | 2013 |
Targeting the cyclin-binding groove site to inhibit the catalytic activity of CDK2/cyclin A complex using p27KIP1-derived peptidomimetic inhibitors A Karthiga, SK Tripathi, R Shanmugam, V Suryanarayanan, SK Singh Journal of chemical biology 8, 11-24, 2015 | 15 | 2015 |
De novo design of ligands using computational methods V Suryanarayanan, U Panwar, I Chandra, SK Singh Computational Drug Discovery and Design, 71-86, 2018 | 14 | 2018 |
Dissecting the structure–function relationship in lysozyme domain of mycobacteriophage D29‐encoded peptidoglycan hydrolase H Joshi, SP Seniya, V Suryanarayanan, ND Patidar, SK Singh, V Jain FEBS letters 591 (20), 3276-3287, 2017 | 12 | 2017 |
Molecular modeling and structural analysis of nAChR variants uncovers the mechanism of resistance to snake toxins D Gunasekaran, J Sridhar, V Suryanarayanan, NC Manimaran, SK Singh Journal of Biomolecular Structure and Dynamics 35 (8), 1654-1671, 2017 | 12 | 2017 |
Structure based identification and biological evaluation of novel and potent inhibitors of PCAF catalytic domain V Suryanarayanan, T Rajavel, KP Devi, SK Singh International journal of biological macromolecules 120, 823-834, 2018 | 11 | 2018 |
Investigating the folding pathway and substrate induced conformational changes in B. malayi Guanylate kinase S Gupta, S Yadav, V Suryanarayanan, SK Singh, JK Saxena International journal of biological macromolecules 94, 621-633, 2017 | 11 | 2017 |
Unravelling novel congeners from acetyllysine mimicking ligand targeting a lysine acetyltransferase PCAF bromodomain V Suryanarayanan, SK Singh Journal of Biomolecular Structure and Dynamics 36 (16), 4303-4319, 2018 | 10 | 2018 |
Explicit drug re-positioning: Predicting novel drug–target interactions of the shelved molecules with qm/mm based approaches A Omer, V Suryanarayanan, C Selvaraj, SK Singh, P Singh Advances in Protein Chemistry and Structural Biology 100, 89-112, 2015 | 9 | 2015 |
Chemopreventive effect of saponin isolated from Gymnema sylevestre on prostate cancer through in silico and in vivo analysis R Pon Nivedha, V Suryanarayanan, C Selvaraj, SK Singh, M Rajalakshmi Medicinal Chemistry Research 26, 1915-1925, 2017 | 8 | 2017 |
Exploration of new and potent lead molecules against CAAX prenyl protease I of Leishmania donovani through Pharmacophore based virtual screening approach S Vijaya Prabhu, K Tiwari, V Suryanarayanan, V Kumar Dubey, ... Combinatorial Chemistry & High Throughput Screening 20 (3), 255-271, 2017 | 6 | 2017 |