CRISPR/Cas9-mediated genome editing as a therapeutic approach for Leber congenital amaurosis 10 GX Ruan, E Barry, D Yu, M Lukason, SH Cheng, A Scaria Molecular therapy 25 (2), 331-341, 2017 | 297 | 2017 |
Retinal dopamine mediates multiple dimensions of light-adapted vision CR Jackson, GX Ruan, F Aseem, J Abey, K Gamble, G Stanwood, ... Journal of Neuroscience 32 (27), 9359-9368, 2012 | 282 | 2012 |
Axl is essential for VEGF‐A‐dependent activation of PI3K/Akt GX Ruan, A Kazlauskas The EMBO journal 31 (7), 1692-1703, 2012 | 249 | 2012 |
Circadian organization of the mammalian retina GX Ruan, DQ Zhang, T Zhou, S Yamazaki, DG McMahon Proceedings of the National Academy of Sciences 103 (25), 9703-9708, 2006 | 206 | 2006 |
Lactate engages receptor tyrosine kinases Axl, Tie2, and vascular endothelial growth factor receptor 2 to activate phosphoinositide 3-kinase/Akt and promote angiogenesis GX Ruan, A Kazlauskas Journal of Biological Chemistry 288 (29), 21161-21172, 2013 | 190 | 2013 |
An autonomous circadian clock in the inner mouse retina regulated by dopamine and GABA GX Ruan, GC Allen, S Yamazaki, DG McMahon PLoS biology 6 (10), e249, 2008 | 174 | 2008 |
Divergent roles of clock genes in retinal and suprachiasmatic nucleus circadian oscillators GX Ruan, KL Gamble, ML Risner, LA Young, DG McMahon PLoS One 7 (6), e38985, 2012 | 67 | 2012 |
VEGF-A engages at least three tyrosine kinases to activate PI3K/Akt GX Ruan, A Kazlauskas Cell Cycle 11 (11), 2047-2048, 2012 | 50 | 2012 |
Mammalian retinal Müller cells have circadian clock function L Xu, G Ruan, H Dai, AC Liu, J Penn, DG McMahon Molecular Vision 22, 275, 2016 | 34 | 2016 |
Circadian rhythm of Period1 clock gene expression in NOS amacrine cells of the mouse retina DQ Zhang, T Zhou, GX Ruan, DG McMahon Brain research 1050 (1-2), 101-109, 2005 | 29 | 2005 |
Focus on molecules: Akt (PKB) GX Ruan, A Kazlauskas Experimental eye research 93 (5), 570, 2010 | 18 | 2010 |
329. Using CRISPR/Cas9 as a therapeutic approach for leber congenital amaurosis 10 (LCA10) G Ruan, E Barry, M Lukason, S Cheng, A Scaria Molecular Therapy 24, S131-S132, 2016 | 5 | 2016 |
Lactate engages receptor tyrosine kinases Axl, Tie2 and VEGFR-2 to activate PI3K/Akt and promote angiogenesis GX Ruan, A Kazlauskas J Biol Chem 288 (29), 21161-72, 2013 | 4 | 2013 |
GENE EDITING OF DEEP INTRONIC MUTATIONS G Ruan, A Scaria US Patent App. 18/399,364, 2024 | | 2024 |
Gene editing of deep intronic mutations R Guoxiang, A Scaria US Patent 11,896,651, 2024 | | 2024 |
深內含子突變的基因編輯 G Ruan, A Scaria | | 2019 |