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Joanne X Shen
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JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality
J Stebbing, G Sánchez Nievas, M Falcone, S Youhanna, P Richardson, ...
Science advances 7 (1), eabe4724, 2021
2042021
Comprehensive evaluation of organotypic and microphysiological liver models for prediction of drug-induced liver injury
Y Zhou, JX Shen, VM Lauschke
Frontiers in pharmacology 10, 1093, 2019
1122019
In vitro and ex vivo models of adipocytes
J Dufau, JX Shen, M Couchet, TDC Barbosa, N Mejhert, L Massier, ...
American Journal of Physiology-Cell Physiology, 2021
932021
3D adipose tissue culture links the organotypic microenvironment to improved adipogenesis
JX Shen, M Couchet, J Dufau, T de Castro Barbosa, MH Ulbrich, ...
Advanced Science 8 (16), 2100106, 2021
562021
Liver macrophages inhibit the endogenous antioxidant response in obesity-associated insulin resistance
V Azzimato, J Jager, P Chen, C Morgantini, L Levi, E Barreby, A Sulen, ...
Science translational medicine 12 (532), eaaw9709, 2020
532020
Hepatic miR-144 drives fumarase activity preventing NRF2 activation during obesity
V Azzimato, P Chen, E Barreby, C Morgantini, L Levi, A Vankova, J Jager, ...
Gastroenterology 161 (6), 1982-1997. e11, 2021
422021
Organotypic and microphysiological models of liver, gut, and kidney for studies of drug metabolism, pharmacokinetics, and toxicity
JX Shen, S Youhanna, R Zandi Shafagh, J Kele, VM Lauschke
Chemical research in toxicology 33 (1), 38-60, 2019
392019
Organotypic and microphysiological human tissue models for drug discovery and development—current state-of-the-art and future perspectives
S Youhanna, AM Kemas, L Preiss, Y Zhou, JX Shen, SD Cakal, ...
Pharmacological Reviews 74 (1), 141-206, 2022
332022
Bioengineered pancreas–liver crosstalk in a microfluidic coculture chip identifies human metabolic response signatures in prediabetic hyperglycemia
R Zandi Shafagh, S Youhanna, J Keulen, JX Shen, N Taebnia, LC Preiss, ...
Advanced Science 9 (34), 2203368, 2022
202022
Facile nanoimprinting of robust high-aspect-ratio nanostructures for human cell biomechanics
R Zandi Shafagh, JX Shen, S Youhanna, W Guo, VM Lauschke, ...
ACS Applied Bio Materials 3 (12), 8757-8767, 2020
122020
Human resident liver myeloid cells protect against metabolic stress in obesity
E Barreby, B Strunz, S Nock, L Naudet, JX Shen, H Johansson, ...
Nature Metabolism 5 (7), 1188-1203, 2023
102023
A gene regulatory network anchored by LIM homeobox 1 for embryonic head development
T Sibbritt, CK Ip, PL Khoo, E Wilkie, V Jones, JQJ Sun, JX Shen, G Peng, ...
genesis 56 (9), e23246, 2018
102018
The effect of blood pressure lowering medications on the prevention of episodic migraine: a systematic review and meta-analysis
C Carcel, F Haghdoost, J Shen, P Nanda, Y Bai, E Atkins, ...
Cephalalgia 43 (6), 03331024231183166, 2023
92023
Gene editing of mouse embryonic and epiblast stem cells
T Sibbritt, P Osteil, X Fan, J Sun, N Salehin, H Knowles, J Shen, PPL Tam
Mouse Cell Culture: Methods and Protocols, 77-95, 2019
52019
Estrogen receptor activation remodels TEAD1 gene expression to alleviate hepatic steatosis
C Sommerauer, CJ Gallardo-Dodd, C Savva, L Hases, M Birgersson, ...
Molecular Systems Biology 20 (4), 374-402, 2024
12024
Estrogen receptor activation remodels TEAD1 gene expression to alleviate nonalcoholic fatty liver disease
C Sommerauer, CJ Gallardo-Dodd, C Savva, L Hases, M Birgersson, ...
bioRxiv, 2023.09. 07.556687, 2023
2023
Novel in Vitro Systems Elucidating Metabolic Health and Disease
JX Shen
PQDT-Global, 2023
2023
Hepatic miR-144 drives fumarase activity preventing NRF2 activation during obesity
V Azzimato, P Chen, E Barreby, C Morgantini, L Levi, A Vankova, J Jager, ...
Journal of Hepatology 77, S665-S666, 2022
2022
Human resident liver macrophages protect against metabolic stress in obesity
E Barreby, B Strunz, V Azzimato, JX Shen, L Naudet, I Sönnerborg, ...
Journal of Hepatology 77, S756-S757, 2022
2022
Deciphering the gene regulatory network necessary for head formation
T Sibbritt, V Jones, CK Ip, E Wilkie, J Shen, J Sun, R Rawson, JB Studdert, ...
Mechanisms of Development, S143, 2017
2017
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