JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality J Stebbing, G Sánchez Nievas, M Falcone, S Youhanna, P Richardson, ... Science advances 7 (1), eabe4724, 2021 | 204 | 2021 |
Comprehensive evaluation of organotypic and microphysiological liver models for prediction of drug-induced liver injury Y Zhou, JX Shen, VM Lauschke Frontiers in pharmacology 10, 1093, 2019 | 112 | 2019 |
In vitro and ex vivo models of adipocytes J Dufau, JX Shen, M Couchet, TDC Barbosa, N Mejhert, L Massier, ... American Journal of Physiology-Cell Physiology, 2021 | 93 | 2021 |
3D adipose tissue culture links the organotypic microenvironment to improved adipogenesis JX Shen, M Couchet, J Dufau, T de Castro Barbosa, MH Ulbrich, ... Advanced Science 8 (16), 2100106, 2021 | 56 | 2021 |
Liver macrophages inhibit the endogenous antioxidant response in obesity-associated insulin resistance V Azzimato, J Jager, P Chen, C Morgantini, L Levi, E Barreby, A Sulen, ... Science translational medicine 12 (532), eaaw9709, 2020 | 53 | 2020 |
Hepatic miR-144 drives fumarase activity preventing NRF2 activation during obesity V Azzimato, P Chen, E Barreby, C Morgantini, L Levi, A Vankova, J Jager, ... Gastroenterology 161 (6), 1982-1997. e11, 2021 | 42 | 2021 |
Organotypic and microphysiological models of liver, gut, and kidney for studies of drug metabolism, pharmacokinetics, and toxicity JX Shen, S Youhanna, R Zandi Shafagh, J Kele, VM Lauschke Chemical research in toxicology 33 (1), 38-60, 2019 | 39 | 2019 |
Organotypic and microphysiological human tissue models for drug discovery and development—current state-of-the-art and future perspectives S Youhanna, AM Kemas, L Preiss, Y Zhou, JX Shen, SD Cakal, ... Pharmacological Reviews 74 (1), 141-206, 2022 | 33 | 2022 |
Bioengineered pancreas–liver crosstalk in a microfluidic coculture chip identifies human metabolic response signatures in prediabetic hyperglycemia R Zandi Shafagh, S Youhanna, J Keulen, JX Shen, N Taebnia, LC Preiss, ... Advanced Science 9 (34), 2203368, 2022 | 20 | 2022 |
Facile nanoimprinting of robust high-aspect-ratio nanostructures for human cell biomechanics R Zandi Shafagh, JX Shen, S Youhanna, W Guo, VM Lauschke, ... ACS Applied Bio Materials 3 (12), 8757-8767, 2020 | 12 | 2020 |
Human resident liver myeloid cells protect against metabolic stress in obesity E Barreby, B Strunz, S Nock, L Naudet, JX Shen, H Johansson, ... Nature Metabolism 5 (7), 1188-1203, 2023 | 10 | 2023 |
A gene regulatory network anchored by LIM homeobox 1 for embryonic head development T Sibbritt, CK Ip, PL Khoo, E Wilkie, V Jones, JQJ Sun, JX Shen, G Peng, ... genesis 56 (9), e23246, 2018 | 10 | 2018 |
The effect of blood pressure lowering medications on the prevention of episodic migraine: a systematic review and meta-analysis C Carcel, F Haghdoost, J Shen, P Nanda, Y Bai, E Atkins, ... Cephalalgia 43 (6), 03331024231183166, 2023 | 9 | 2023 |
Gene editing of mouse embryonic and epiblast stem cells T Sibbritt, P Osteil, X Fan, J Sun, N Salehin, H Knowles, J Shen, PPL Tam Mouse Cell Culture: Methods and Protocols, 77-95, 2019 | 5 | 2019 |
Estrogen receptor activation remodels TEAD1 gene expression to alleviate hepatic steatosis C Sommerauer, CJ Gallardo-Dodd, C Savva, L Hases, M Birgersson, ... Molecular Systems Biology 20 (4), 374-402, 2024 | 1 | 2024 |
Estrogen receptor activation remodels TEAD1 gene expression to alleviate nonalcoholic fatty liver disease C Sommerauer, CJ Gallardo-Dodd, C Savva, L Hases, M Birgersson, ... bioRxiv, 2023.09. 07.556687, 2023 | | 2023 |
Novel in Vitro Systems Elucidating Metabolic Health and Disease JX Shen PQDT-Global, 2023 | | 2023 |
Hepatic miR-144 drives fumarase activity preventing NRF2 activation during obesity V Azzimato, P Chen, E Barreby, C Morgantini, L Levi, A Vankova, J Jager, ... Journal of Hepatology 77, S665-S666, 2022 | | 2022 |
Human resident liver macrophages protect against metabolic stress in obesity E Barreby, B Strunz, V Azzimato, JX Shen, L Naudet, I Sönnerborg, ... Journal of Hepatology 77, S756-S757, 2022 | | 2022 |
Deciphering the gene regulatory network necessary for head formation T Sibbritt, V Jones, CK Ip, E Wilkie, J Shen, J Sun, R Rawson, JB Studdert, ... Mechanisms of Development, S143, 2017 | | 2017 |