Staphylococcus aureus colonization: modulation of host immune response and impact on human vaccine design AF Brown, JM Leech, TR Rogers, RM McLoughlin Frontiers in immunology 4, 72999, 2014 | 309 | 2014 |
Alteration of the cutaneous microbiome in psoriasis and potential role in Th17 polarization HW Chang, D Yan, R Singh, J Liu, X Lu, D Ucmak, K Lee, L Afifi, ... Microbiome 6, 1-27, 2018 | 238 | 2018 |
Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection AF Brown, AG Murphy, SJ Lalor, JM Leech, KM O’Keeffe, M Mac Aogáin, ... PLoS pathogens 11 (11), e1005226, 2015 | 170 | 2015 |
Manipulation of autophagy in phagocytes facilitates Staphylococcus aureus bloodstream infection KM O'Keeffe, MM Wilk, JM Leech, AG Murphy, M Laabei, IR Monk, ... Infection and immunity 83 (9), 3445-3457, 2015 | 106 | 2015 |
IL-10 plays opposing roles during Staphylococcus aureus systemic and localized infections JM Leech, KA Lacey, ME Mulcahy, E Medina, RM McLoughlin The Journal of Immunology 198 (6), 2352-2365, 2017 | 89 | 2017 |
Promoting transplantation tolerance; adoptive regulatory T cell therapy N Safinia, J Leech, M Hernandez-Fuentes, R Lechler, G Lombardi Clinical & Experimental Immunology 172 (2), 158-168, 2013 | 82 | 2013 |
Toxin-triggered interleukin-1 receptor signaling enables early-life discrimination of pathogenic versus commensal skin bacteria JM Leech, MO Dhariwala, MM Lowe, K Chu, GR Merana, C Cornuot, ... Cell host & microbe 26 (6), 795-809. e5, 2019 | 70 | 2019 |
Interleukin-22 regulates antimicrobial peptide expression and keratinocyte differentiation to control Staphylococcus aureus colonization of the nasal mucosa ME Mulcahy, JM Leech, JC Renauld, KHG Mills, RM McLoughlin Mucosal immunology 9 (6), 1429-1441, 2016 | 65 | 2016 |
Evidence of potent humoral immune activity in COVID-19-infected kidney transplant recipients S Hartzell, S Bin, C Benedetti, M Haverly, L Gallon, G Zaza, LV Riella, ... American Journal of Transplantation 20 (11), 3149-3161, 2020 | 62 | 2020 |
Regulatory T cells promote innate inflammation after skin barrier breach via TGF-β activation JM Moreau, MO Dhariwala, V Gouirand, DP Boda, IC Boothby, MM Lowe, ... Science immunology 6 (62), eabg2329, 2021 | 33 | 2021 |
Sampling the host response to SARS-CoV-2 in hospitals under siege AW Charney, NW Simons, K Mouskas, L Lepow, E Cheng, J Le Berichel, ... Nature Medicine 26 (8), 1157-1158, 2020 | 30 | 2020 |
A streamlined whole blood CyTOF workflow defines a circulating immune cell signature of COVID‐19 D Geanon, B Lee, E Gonzalez‐Kozlova, G Kelly, D Handler, B Upadhyaya, ... Cytometry Part A 99 (5), 446-461, 2021 | 29 | 2021 |
The Staphylococcus aureus cell wall-anchored protein clumping factor A is an important T cell antigen KA Lacey, JM Leech, SJ Lalor, N McCormack, JA Geoghegan, ... Infection and immunity 85 (12), 10.1128/iai. 00549-17, 2017 | 29 | 2017 |
Long-term tolerance to skin commensals is established neonatally through a specialized dendritic cell subgroup A Weckel, MO Dhariwala, K Ly, VM Tran, OT Ojewumi, JB Riggs, ... Immunity 56 (6), 1239-1254. e7, 2023 | 19 | 2023 |
Whole-body imaging of adoptively transferred T cells using magnetic resonance imaging, single photon emission computed tomography and positron emission tomography techniques … JM Leech, E Sharif-Paghaleh, J Maher, L Livieratos, RI Lechler, ... Clinical & Experimental Immunology 172 (2), 169-177, 2013 | 17 | 2013 |
Monitoring the efficacy of dendritic cell vaccination by early detection of 99mTc‐HMPAO‐labelled CD4+ T cells E Sharif‐Paghaleh, J Leech, K Sunassee, N Ali, P Sagoo, RI Lechler, ... European Journal of Immunology 44 (7), 2188-2191, 2014 | 11 | 2014 |
Staphylococcus aureus-induced immunosuppression mediated by IL-10 and IL-27 facilitates nasal colonisation AM Kelly, JM Leech, SL Doyle, RM McLoughlin PLoS Pathogens 18 (7), e1010647, 2022 | 10 | 2022 |
A streamlined CyTOF workflow to facilitate standardized multi-site immune profiling of COVID-19 patients D Geanon, B Lee, G Kelly, D Handler, B Upadhyaya, J Leech, M Herbinet, ... medRxiv, 2020.06. 26.20141341, 2020 | 10 | 2020 |
Seasonal variation in the Canastra cheese mycobiota JGP Martin, JMM Silva, ICR Cesar, M da Silva, SA Santana, TGR Veloso, ... Frontiers in microbiology 13, 1076672, 2023 | 5 | 2023 |
Commensal myeloid crosstalk in neonatal skin regulates long-term cutaneous type 17 inflammation MO Dhariwala, AM DeRogatis, JN Okoro, A Weckel, VM Tran, I Habrylo, ... bioRxiv, 2023 | 1 | 2023 |