| A critical role for IGF-II in memory consolidation and enhancement DY Chen, SA Stern, A Garcia-Osta, B Saunier-Rebori, G Pollonini, ... Nature 469 (7331), 491-497, 2011 | 480 | 2011 |
| Phenylbutyrate ameliorates cognitive deficit and reduces tau pathology in an Alzheimer's disease mouse model A Ricobaraza, M Cuadrado-Tejedor, A Pérez-Mediavilla, D Frechilla, ... Neuropsychopharmacology 34 (7), 1721-1732, 2009 | 462 | 2009 |
| Phenylbutyrate rescues dendritic spine loss associated with memory deficits in a mouse model of Alzheimer disease A Ricobaraza, M Cuadrado‐Tejedor, S Marco, I Pérez‐Otaño, ... Hippocampus 22 (5), 1040-1050, 2012 | 294 | 2012 |
| Phosphodiesterases as therapeutic targets for Alzheimer's disease A García-Osta, M Cuadrado-Tejedor, C García-Barroso, J Oyarzabal, ... ACS chemical neuroscience 3 (11), 832-844, 2012 | 274 | 2012 |
| Rosiglitazone rescues memory impairment in Alzheimer's transgenic mice: mechanisms involving a reduced amyloid and tau pathology L Escribano, AM Simón, E Gimeno, M Cuadrado-Tejedor, ... Neuropsychopharmacology 35 (7), 1593-1604, 2010 | 272 | 2010 |
| Sildenafil restores cognitive function without affecting β‐amyloid burden in a mouse model of Alzheimer's disease M Cuadrado‐Tejedor, I Hervias, A Ricobaraza, E Puerta, ... British journal of pharmacology 164 (8), 2029-2041, 2011 | 223 | 2011 |
| Amyloid beta mediates memory formation A Garcia-Osta, CM Alberini Learning & memory 16 (4), 267-272, 2009 | 217 | 2009 |
| Tadalafil crosses the blood–brain barrier and reverses cognitive dysfunction in a mouse model of AD C García-Barroso, A Ricobaraza, M Pascual-Lucas, N Unceta, AJ Rico, ... Neuropharmacology 64, 114-123, 2013 | 187 | 2013 |
| Insulin‐like growth factor 2 reverses memory and synaptic deficits in APP transgenic mice M Pascual‐Lucas, S Viana da Silva, M Di Scala, C Garcia‐Barroso, ... EMBO molecular medicine 6 (10), 1246-1262, 2014 | 144 | 2014 |
| Decreased levels of guanosine 3′, 5′‐monophosphate (c GMP) in cerebrospinal fluid (CSF) are associated with cognitive decline and amyloid pathology in A lzheimer's disease A Ugarte, F Gil‐Bea, C García‐Barroso, Á Cedazo‐Minguez, MJ Ramírez, ... Neuropathology and applied neurobiology 41 (4), 471-482, 2015 | 109 | 2015 |
| MuSK expressed in the brain mediates cholinergic responses, synaptic plasticity, and memory formation A Garcia-Osta, P Tsokas, G Pollonini, EM Landau, R Blitzer, CM Alberini Journal of Neuroscience 26 (30), 7919-7932, 2006 | 108 | 2006 |
| BDNF mediates the neuroprotective effect of PACAP-38 on rat cortical neurons D Frechilla, A García-Osta, S Palacios, E Cenarruzabeitia, J Del Río Neuroreport 12 (5), 919-923, 2001 | 105 | 2001 |
| A first-in-class small-molecule that acts as a dual inhibitor of HDAC and PDE5 and that rescues hippocampal synaptic impairment in Alzheimer’s disease mice M Cuadrado-Tejedor, C Garcia-Barroso, JA Sánchez-Arias, O Rabal, ... Neuropsychopharmacology 42 (2), 524-539, 2017 | 104 | 2017 |
| Phosphodiesterase‐5 inhibitors: action on the signaling pathways of neuroinflammation, neurodegeneration, and cognition CA Peixoto, AKS Nunes, A Garcia-Osta Mediators of Inflammation 2015 (1), 940207, 2015 | 103 | 2015 |
| Targeting RNA-mediated toxicity in C9orf72 ALS and/or FTD by RNAi-based gene therapy R Martier, JM Liefhebber, A García-Osta, J Miniarikova, ... Molecular Therapy-Nucleic Acids 16, 26-37, 2019 | 97 | 2019 |
| Design, synthesis, and biological evaluation of first-in-class dual acting histone deacetylases (HDACs) and phosphodiesterase 5 (PDE5) inhibitors for the treatment of Alzheimer … O Rabal, JA Sánchez-Arias, M Cuadrado-Tejedor, I de Miguel, ... Journal of medicinal chemistry 59 (19), 8967-9004, 2016 | 87 | 2016 |
| Sildenafil protects against 3-nitropropionic acid neurotoxicity through the modulation of calpain, CREB, and BDNF E Puerta, I Hervias, L Barros-Miñones, J Jordan, A Ricobaraza, ... Neurobiology of disease 38 (2), 237-245, 2010 | 86 | 2010 |
| Chronic mild stress accelerates the onset and progression of the Alzheimer's disease phenotype in Tg2576 mice M Cuadrado-Tejedor, A Ricobaraza, D Frechilla, R Franco, ... Journal of Alzheimer's Disease 28 (3), 567-578, 2012 | 76 | 2012 |
| Phenylbutyrate is a multifaceted drug that exerts neuroprotective effects and reverses the Alzheimer s disease-like phenotype of a commonly used mouse model M Cuadrado-Tejedor, A L. Ricobaraza, R Torrijo, R Franco, A Garcia-Osta Current pharmaceutical design 19 (28), 5076-5084, 2013 | 74 | 2013 |
| Differential Regulation by Methylenedioxymethamphetamine of 5‐Hydroxytryptamine1A Receptor Density and mRNA Expression in Rat Hippocampus, Frontal … N Aguirre, D Frechilla, A García‐Osta, B Lasheras, JI Del RIo Journal of neurochemistry 68 (3), 1099-1105, 1997 | 70 | 1997 |
