Inhibition of NGLY1 inactivates the transcription factor Nrf1 and potentiates proteasome inhibitor cytotoxicity FM Tomlin, UIM Gerling-Driessen, YC Liu, RA Flynn, JR Vangala, ... ACS central science 3 (11), 1143-1155, 2017 | 188 | 2017 |
Design and synthesis of resveratrol-based nitrovinylstilbenes as antimitotic agents MA Reddy, N Jain, D Yada, C Kishore, JR Vangala, R P. Surendra, ... Journal of medicinal chemistry 54 (19), 6751-6760, 2011 | 96 | 2011 |
Regulation of PSMB5 protein and β subunits of mammalian proteasome by constitutively activated signal transducer and activator of transcription 3 (STAT3): potential role in … JR Vangala, S Dudem, N Jain, SV Kalivendi Journal of Biological Chemistry 289 (18), 12612-12622, 2014 | 74 | 2014 |
Nrf1 can be processed and activated in a proteasome-independent manner JR Vangala, F Sotzny, E Krüger, RJ Deshaies, SK Radhakrishnan Current Biology 26 (18), R834-R835, 2016 | 43 | 2016 |
Disabling the protease DDI2 attenuates the transcriptional activity of NRF1 and potentiates proteasome inhibitor cytotoxicity A Northrop, JR Vangala, A Feygin, SK Radhakrishnan International journal of molecular sciences 21 (1), 327, 2020 | 36 | 2020 |
Stereoselective total synthesis of (+)-oploxyne A,(−)-oploxyne B, and their C-10 epimers and structure revision of natural oploxyne B JS Yadav, K Boyapelly, SR Alugubelli, S Pabbaraja, JR Vangala, ... The Journal of Organic Chemistry 76 (8), 2568-2576, 2011 | 31 | 2011 |
Nrf1-mediated transcriptional regulation of the proteasome requires a functional TIP60 complex JR Vangala, SK Radhakrishnan Journal of Biological Chemistry 294 (6), 2036-2045, 2019 | 26 | 2019 |
Two new sesquiterpenoids from the rhizomes of Nardostachys jatamansi K Rekha, RR Rao, R Pandey, KR Prasad, KS Babu, JR Vangala, ... Journal of Asian natural products research 15 (2), 111-116, 2013 | 25 | 2013 |
BET inhibitors synergize with carfilzomib to induce cell death in cancer cells via impairing Nrf1 transcriptional activity and exacerbating the unfolded protein response JR Vangala, A Potluri, SK Radhakrishnan Biomolecules 10 (4), 501, 2020 | 19 | 2020 |
Inhibition of NGLY1 inactivates the transcription factor Nrf1 and potentiates proteasome inhibitor cytotoxicity. ACS Cent Sci 3: 1143–1155 FM Tomlin, UIM Gerling-Driessen, YC Liu, RA Flynn, JR Vangala, ... PLoS Genet 13, e1006696, 2017 | 9 | 2017 |
Inhibition of NGLY1 Inactivates the Transcription Factor Nrf1 and Potentiates Proteasome Inhibitor Cytotoxicity. ACS Central Science, 3 (11), 1143–1155 FM Tomlin, UIM Gerling-Driessen, YC Liu, RA Flynn, JR Vangala, ... | 5 | 2017 |
Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy MA Ward, JR Vangala, HE Kamber Kaya, HA Byers, N Hosseini, A Diaz, ... Journal of Cell Biology 223 (6), e202306150, 2024 | 3 | 2024 |
Evaluation of the NRF1-proteasome axis as a therapeutic target in breast cancer HA Byers, AN Brooks, JR Vangala, JM Grible, A Feygin, CV Clevenger, ... Scientific Reports 13 (1), 15843, 2023 | 3 | 2023 |
R, PS; Addlagatta, A.; Kalivendi, SV; Sreedhar, B. Design and synthesis of resveratrol-based nitrovinylstilbenes as antimitotic agents MA Reddy, N Jain, D Yada, C Kishore, JR Vangala J. Med. Chem 54 (19), 6751-6760, 2011 | 3 | 2011 |
Regulation of PSMB5 and β-subunits of mammalian proteasome by constitutively activated STAT3: potential role in Bortezomib mediated anticancer therapy GR Vangala, S Dudem, N Jain, SD Kaliventi J Biol Chem 113, 542829, 2014 | 2 | 2014 |
Inhibition of NGLY1 inactivates the transcription factor Nrf1 and potentiates proteasome inhibitor cytotoxicity C Bertozzi, F Tomlin, U Gerling-Driessen, YC Liu, R Flynn, J Vangala, ... | 1 | 2017 |
Abstract 1541 Transcription factor Nrf1 regulates proteotoxic stress-induced autophagy S Radhakrishnan, M Ward, J Vangala, HEK Kaya Journal of Biological Chemistry 300 (3), 2024 | | 2024 |
Transcriptional Regulation of the Proteasome: Implications for Cancer Therapy S Radhakrishnan, J Vangala The FASEB Journal 34 (S1), 1-1, 2020 | | 2020 |
Proteotoxic stress-induced Nrf1 transcriptional program requires a functional TIP60 complex JR Vangala, SK Radhakrishnan bioRxiv, 443937, 2018 | | 2018 |
Role of STATS in the regulation of Mammalian Proteasome: Implications for cancer and proteasome associated disorders VJ Reddy | | 2014 |