The first-in-class peptide binder to the SARS-CoV-2 spike protein G Zhang, S Pomplun, AR Loftis, A Loas, BL Pentelute BioRxiv 10 (2020.03), 19.999318, 2020 | 115 | 2020 |
Investigation of ACE2 N-terminal fragments binding to SARS-CoV-2 Spike RBD G Zhang, S Pomplun, AR Loftis, X Tan, A Loas, BL Pentelute BioRxiv, 2020.03. 19.999318, 2020 | 90 | 2020 |
De Novo Discovery of High-Affinity Peptide Binders for the SARS-CoV-2 Spike Protein S Pomplun, M Jbara, AJ Quartararo, G Zhang, JS Brown, YC Lee, X Ye, ... ACS central science 7 (1), 156-163, 2020 | 78 | 2020 |
Chemogenomic profiling of human and microbial FK506-binding proteins S Pomplun, C Sippel, A Hähle, D Tay, K Shima, A Klages, CM Ünal, ... Journal of medicinal chemistry 61 (8), 3660-3673, 2018 | 64 | 2018 |
Rational Design and Asymmetric Synthesis of Potent and Neurotrophic Ligands for FK506‐Binding Proteins (FKBPs) S Pomplun, Y Wang, A Kirschner, C Kozany, A Bracher, F Hausch Angewandte Chemie International Edition 54 (1), 345-348, 2015 | 41 | 2015 |
Targeting the SARS-CoV-2-spike protein: from antibodies to miniproteins and peptides S Pomplun RSC Medicinal Chemistry 12 (2), 197-202, 2021 | 39 | 2021 |
Engineering bioactive dimeric transcription factor analogs via palladium rebound reagents M Jbara, S Pomplun, CK Schissel, SW Hawken, A Boija, I Klein, ... Journal of the American Chemical Society 143 (30), 11788-11798, 2021 | 31 | 2021 |
Recent progress in FKBP ligand development X Feng, S Pomplun, F Hausch Current molecular pharmacology 9 (1), 27-36, 2016 | 27 | 2016 |
Picomolar FKBP inhibitors enabled by a single water-displacing methyl group in bicyclic [4.3. 1] aza-amides JM Kolos, S Pomplun, S Jung, B Rieß, PL Purder, AM Voll, S Merz, ... Chemical science 12 (44), 14758-14765, 2021 | 26 | 2021 |
Loratadine and Analogues: Discovery and Preliminary Structure–Activity Relationship of Inhibitors of the Amino Acid Transporter B0AT2 S Cuboni, C Devigny, B Hoogeland, A Strasser, S Pomplun, B Hauger, ... Journal of medicinal chemistry 57 (22), 9473-9479, 2014 | 26 | 2014 |
Discovery of nucleic acid binding molecules from combinatorial biohybrid nucleobase peptide libraries S Pomplun, ZP Gates, G Zhang, AJ Quartararo, BL Pentelute Journal of the American Chemical Society 142 (46), 19642-19651, 2020 | 25 | 2020 |
Efficient Pictet–Spengler Bioconjugation with N‐Substituted Pyrrolyl Alanine Derivatives S Pomplun, MYH Mohamed, T Oelschlaegel, C Wellner, F Bergmann Angewandte Chemie 131 (11), 3580-3585, 2019 | 23 | 2019 |
Parallel automated flow synthesis of covalent protein complexes that can inhibit MYC-driven transcription S Pomplun, M Jbara, CK Schissel, S Wilson Hawken, A Boija, C Li, I Klein, ... ACS Central Science 7 (8), 1408-1418, 2021 | 22 | 2021 |
Secondary amino alcohols: traceless cleavable linkers for use in affinity capture and release S Pomplun, CR Shugrue, AM Schmitt, CK Schissel, CE Farquhar, ... Angewandte Chemie International Edition 59 (28), 11566-11572, 2020 | 12 | 2020 |
Advances in ultrahigh throughput hit discovery with tandem mass spectrometry encoded libraries JM Mata, E van der Nol, SJ Pomplun Journal of the American Chemical Society 145 (34), 19129-19139, 2023 | 7 | 2023 |
Rationales Design und asymmetrische Synthese potenter neuritotropher Liganden für FK506‐bindende Proteine (FKBPs) S Pomplun, Y Wang, A Kirschner, C Kozany, A Bracher, F Hausch Angewandte Chemie 127 (1), 352-355, 2015 | 5 | 2015 |
Synthetic Peptides: Promising Modalities for the Targeting of Disease‐Related Nucleic Acids BD Ellenbroek, JP Kahler, SR Evers, SJ Pomplun Angewandte Chemie International Edition 63 (20), e202401704, 2024 | 3 | 2024 |
Automated flow peptide synthesis enables engineering of proteins with stabilized transient binding pockets A Charalampidou, T Nehls, C Meyners, S Gandhesiri, S Pomplun, ... ACS Central Science 10 (3), 649-657, 2024 | 1 | 2024 |
Use of DNA forceps to measure receptor-ligand dissociation equilibrium constants in a single-molecule competition assay. F Stransky, D Kostrz, M Follenfant, S Pomplun, C Meyners, T Strick, ... Methods in Enzymology 694, 51-82, 2024 | 1 | 2024 |
Development of DuoMYC: a synthetic cell penetrant miniprotein that efficiently inhibits the oncogenic transcription factor MYC S Pomplun, B Ellenbroek, JP Kahler, D Arella, C Lin, W Jespers bioRxiv, 2024.03. 04.583305, 2024 | 1 | 2024 |