Inhibitory effect of tumor cell–derived lactic acid on human T cells K Fischer, P Hoffmann, S Voelkl, N Meidenbauer, J Ammer, M Edinger, ... Blood 109 (9), 3812-3819, 2007 | 1901 | 2007 |
LDHA-associated lactic acid production blunts tumor immunosurveillance by T and NK cells A Brand, K Singer, GE Koehl, M Kolitzus, G Schoenhammer, A Thiel, ... Cell metabolism 24 (5), 657-671, 2016 | 1426 | 2016 |
Tumor-derived lactic acid modulates dendritic cell activation and antigen expression E Gottfried, LA Kunz-Schughart, S Ebner, W Mueller-Klieser, S Hoves, ... Blood 107 (5), 2013-2021, 2006 | 738 | 2006 |
Metagenomic analysis of the stool microbiome in patients receiving allogeneic stem cell transplantation: loss of diversity is associated with use of systemic antibiotics and … E Holler, P Butzhammer, K Schmid, C Hundsrucker, J Koestler, K Peter, ... Biology of Blood and Marrow Transplantation 20 (5), 640-645, 2014 | 548 | 2014 |
Multicellular spheroids: a threedimensional in vitro culture system to study tumour biology LA KUNZSCHUGHART, M Kreutz, R Knuechel International journal of experimental pathology 79 (1), 1-23, 1998 | 464 | 1998 |
Serum dehydroepiandrosterone (DHEA) and DHEA sulfate are negatively correlated with serum interleukin-6 (IL-6), and DHEA inhibits IL-6 secretion from mononuclear cells in man … RH Straub, L Konecna, S Hrach, G Rothe, M Kreutz, J Scholmerich, ... The Journal of Clinical Endocrinology & Metabolism 83 (6), 2012-2017, 1998 | 444 | 1998 |
Lactic acid and acidification inhibit TNF secretion and glycolysis of human monocytes K Dietl, K Renner, K Dettmer, B Timischl, K Eberhart, C Dorn, ... The Journal of Immunology 184 (3), 1200-1209, 2010 | 432 | 2010 |
GLUT1 expression is increased in hepatocellular carcinoma and promotes tumorigenesis T Amann, U Maegdefrau, A Hartmann, A Agaimy, J Marienhagen, ... The American journal of pathology 174 (4), 1544-1552, 2009 | 389 | 2009 |
Metabolic hallmarks of tumor and immune cells in the tumor microenvironment K Renner, K Singer, GE Koehl, EK Geissler, K Peter, PJ Siska, M Kreutz Frontiers in immunology 8, 248, 2017 | 369 | 2017 |
Tumor immunoevasion via acidosis-dependent induction of regulatory tumor-associated macrophages T Bohn, S Rapp, N Luther, M Klein, TJ Bruehl, N Kojima, P Aranda Lopez, ... Nature immunology 19 (12), 1319-1329, 2018 | 353 | 2018 |
Regulation of 25-hydroxyvitamin D3-1α-hydroxylase and production of 1α,25-dihydroxyvitamin D3 by human dendritic cells J Fritsche, K Mondal, A Ehrnsperger, R Andreesen, M Kreutz Blood 102 (9), 3314-3316, 2003 | 340 | 2003 |
1, 25-dihydroxyvitamin D3 production and vitamin D3 receptor expression are developmentally regulated during differentiation of human monocytes into macrophages M Kreutz, R Andreesen, SW Krause, A Szabo, E Ritz, H Reichel | 312 | 1993 |
Expression of CD68 in nonmyeloid cell types E Gottfried, LA KunzSchughart, A Weber, M Rehli, A Peuker, A Müller, ... Scandinavian journal of immunology 67 (5), 453-463, 2008 | 305 | 2008 |
Tumor lactic acidosis suppresses CTL function by inhibition of p38 and JNK/cJun activation AN Mendler, B Hu, PU Prinz, M Kreutz, E Gottfried, E Noessner International journal of cancer 131 (3), 633-640, 2012 | 294 | 2012 |
Lactate promotes glioma migration by TGF-β2–dependent regulation of matrix metalloproteinase-2 F Baumann, P Leukel, A Doerfelt, CP Beier, K Dettmer, PJ Oefner, ... Neuro-oncology 11 (4), 368-380, 2009 | 291 | 2009 |
CD137 (ILA/4-1BB), a member of the TNF receptor family, induces monocyte activation via bidirectional signaling J Langstein, J Michel, J Fritsche, M Kreutz, R Andreesen, H Schwarz The Journal of Immunology 160 (5), 2488-2494, 1998 | 256 | 1998 |
Surface phenotype analysis of human monocyte to macrophage maturation R Andreesen, W Brugger, C Scheibenbogen, M Kreutz, HG Leser, ... Journal of leukocyte biology 47 (6), 490-497, 1990 | 249 | 1990 |
Restricting glycolysis preserves T cell effector functions and augments checkpoint therapy K Renner, C Bruss, A Schnell, G Koehl, HM Becker, M Fante, ... Cell reports 29 (1), 135-150. e9, 2019 | 247 | 2019 |
Reverse signaling through transmembrane TNF confers resistance to lipopolysaccharide in human monocytes and macrophages G Eissner, S Kirchner, H Lindner, W Kolch, P Janosch, M Grell, ... The Journal of Immunology 164 (12), 6193-6198, 2000 | 246 | 2000 |
Differential screening identifies genetic markers of monocyte to macrophage maturation SW Krause, M Rehli, M Kreutz, L Schwarzfischer, JD Paulauskis, ... Journal of leukocyte biology 60 (4), 540-545, 1996 | 241 | 1996 |