Transformative network modeling of multi-omics data reveals detailed circuits, key regulators, and potential therapeutics for Alzheimer’s disease M Wang, A Li, M Sekiya, ND Beckmann, X Quan, N Schrode, ... Neuron 109 (2), 257-272. e14, 2021 | 144 | 2021 |
Neuronal impact of patient-specific aberrant NRXN1α splicing E Flaherty, S Zhu, N Barretto, E Cheng, PJM Deans, MB Fernando, ... Nature genetics 51 (12), 1679-1690, 2019 | 117 | 2019 |
Common genetic variation in humans impacts in vitro susceptibility to SARS-CoV-2 infection K Dobrindt, DA Hoagland, C Seah, B Kassim, CP O'Shea, A Murphy, ... Stem Cell Reports 16 (3), 505-518, 2021 | 59 | 2021 |
The three-dimensional landscape of cortical chromatin accessibility in Alzheimer’s disease J Bendl, ME Hauberg, K Girdhar, E Im, JM Vicari, S Rahman, ... Nature neuroscience 25 (10), 1366-1378, 2022 | 46 | 2022 |
ASCL1-and DLX2-induced GABAergic neurons from hiPSC-derived NPCs N Barretto, H Zhang, SK Powell, MB Fernando, S Zhang, EK Flaherty, ... Journal of neuroscience methods 334, 108548, 2020 | 44 | 2020 |
Modeling the complex genetic architectures of brain disease MB Fernando, T Ahfeldt, KJ Brennand Nature genetics 52 (4), 363-369, 2020 | 43 | 2020 |
Population-level variation in enhancer expression identifies disease mechanisms in the human brain P Dong, GE Hoffman, P Apontes, J Bendl, S Rahman, MB Fernando, ... Nature genetics 54 (10), 1493-1503, 2022 | 36* | 2022 |
Induced pluripotent stem cells in psychiatry: an overview and critical perspective A De Los Angeles, MB Fernando, NAL Hall, KJ Brennand, PJ Harrison, ... Biological psychiatry 90 (6), 362-372, 2021 | 31 | 2021 |
Lineage specific 3D genome structure in the adult human brain and neurodevelopmental changes in the chromatin interactome S Rahman, P Dong, P Apontes, MB Fernando, R Kosoy, KG Townsley, ... Nucleic acids research 51 (20), 11142-11161, 2023 | 15* | 2023 |
Integrating CRISPR engineering and hiPSC-derived 2D disease modeling systems K Rehbach, MB Fernando, KJ Brennand Journal of Neuroscience 40 (6), 1176-1185, 2020 | 15 | 2020 |
Precise Therapeutic Targeting of Distinct NRXN1+/− Mutations MB Fernando, Y Fan, Y Zhang, S Kammourh, AN Murphy, S Ghorbani, ... bioRxiv, 2023 | 3 | 2023 |
Upregulated GIRK2 counteracts ethanol-induced changes in excitability and respiration in human neurons I Prytkova, Y Liu, M Fernando, I Gameiro-Ros, D Popova, C Kamarajan, ... Journal of Neuroscience 44 (16), 2024 | 2 | 2024 |
Functional genomics of psychiatric disease risk using genome engineering MF Garcia, SK Powell, EA LaMarca, MB Fernando, S Cohen, G Fang, ... Epigenetics in Psychiatry, 711-734, 2021 | 2 | 2021 |
R-loop landscapes in the developing human brain are linked to neural differentiation and cell-type specific transcription EA LaMarca, A Saito, A Plaza-Jennings, S Espeso-Gil, A Hellmich, ... bioRxiv, 2023 | 1 | 2023 |
Quickly moving too slowly: Interneuron migration in Timothy Syndrome MB Fernando, KJ Brennand Cell Stem Cell 29 (2), 181-183, 2022 | | 2022 |
Cross-Platform Validation of 15q13. 3 Microdeletion Network Effects in Human Neurons MB Fernando Biological Psychiatry 89 (5), e25-e27, 2021 | | 2021 |