The requirement for cobalt in vitamin B12: A paradigm for protein metalation D Osman, A Cooke, TR Young, E Deery, NJ Robinson, MJ Warren Biochimica et Biophysica Acta (BBA)-Molecular Cell Research, 118896, 2020 | 127 | 2020 |
An integrated study of the affinities of the Aβ16 peptide for Cu (I) and Cu (II): implications for the catalytic production of reactive oxygen species TR Young, A Kirchner, AG Wedd, Z Xiao Metallomics 6 (3), 505-517, 2014 | 73 | 2014 |
Protein metalation in biology AW Foster, TR Young, PT Chivers, NJ Robinson Current Opinion in Chemical Biology 66, 102095, 2022 | 62 | 2022 |
Copper binding and redox chemistry of the Aβ16 peptide and its variants: insights into determinants of copper-dependent reactivity N Yako, TR Young, JMC Jones, CA Hutton, AG Wedd, Z Xiao Metallomics 9 (3), 278-291, 2017 | 47 | 2017 |
Calculating metalation in cells reveals CobW acquires CoII for vitamin B12 biosynthesis while related proteins prefer ZnII TR Young, MA Martini, AW Foster, A Glasfeld, D Osman, RJ Morton, ... Nature Communications 12 (1), 1195, 2021 | 45 | 2021 |
Principles and practice of determining metal–protein affinities TR Young, Z Xiao Biochemical Journal 478 (5), 1085-1116, 2021 | 34 | 2021 |
CopC Protein from Pseudomonas fluorescens SBW25 Features a Conserved Novel High-Affinity Cu(II) Binding Site CJK Wijekoon, TR Young, AG Wedd, Z Xiao Inorganic chemistry 54 (6), 2950-2959, 2015 | 33 | 2015 |
A set of robust fluorescent peptide probes for quantification of Cu (II) binding affinities in the micromolar to femtomolar range TR Young, CJK Wijekoon, B Spyrou, PS Donnelly, AG Wedd, Z Xiao Metallomics 7 (3), 567-578, 2015 | 33 | 2015 |
Quantification of copper binding to amyloid precursor protein domain 2 and its Caenorhabditis elegans ortholog. Implications for biological function SL Leong, TR Young, KJ Barnham, AG Wedd, MG Hinds, Z Xiao, ... Metallomics 6 (1), 105-116, 2014 | 23 | 2014 |
Evaluation of Cu (i) binding to the E2 domain of the amyloid precursor protein–a lesson in quantification of metal binding to proteins via ligand competition TR Young, AG Wedd, Z Xiao Metallomics 10 (1), 108-119, 2018 | 22 | 2018 |
Acquisition of ionic copper by the bacterial outer membrane protein OprC through a novel binding site SP Bhamidimarri, TR Young, M Shanmugam, S Soderholm, A Baslé, ... PLoS biology 19 (11), e3001446, 2021 | 21 | 2021 |
The Human Amyloid Precursor Protein Binds Copper Ions Dominated by a Picomolar-Affinity Site in the Helix-Rich E2 Domain TR Young, TL Pukala, R Cappai, AG Wedd, Z Xiao Biochemistry 57 (28), 4165-4176, 2018 | 20 | 2018 |
Metalation calculators for E. coli strain JM109 (DE3): aerobic, anaerobic, and hydrogen peroxide exposed cells cultured in LB media AW Foster, SE Clough, Z Aki, TR Young, AR Clarke, NJ Robinson Metallomics 14 (9), mfac058, 2022 | 18 | 2022 |
Insights into the antibacterial mechanism of action of chelating agents by selective deprivation of iron, manganese and zinc JR Paterson, MS Beecroft, RS Mulla, D Osman, NL Reeder, JA Caserta, ... Applied and Environmental Microbiology, AEM. 01641-21, 2021 | 16 | 2021 |
Two Distinct Thermodynamic Gradients for Cellular Metalation of Vitamin B12 TR Young, E Deery, AW Foster, MA Martini, D Osman, MJ Warren, ... JACS Au 3 (5), 1472-1483, 2023 | 5 | 2023 |
Acquisition of ionic copper by a bacterial outer membrane protein SP Bhamidimarri, TR Young, M Shanmugam, S Soderholm, A Baslé, ... bioRxiv, 2020.06. 04.134395, 2020 | 3 | 2020 |
Calculating metalation in cells reveals CobW acquires CoII for vitamin B12 biosynthesis upon binding nucleotide TR Young, MA Martini, D Osman, RJ Morton, E Deery, MJ Warren, ... BioRxiv, 2020.06. 26.173062, 2020 | 2 | 2020 |
Hyperaerated metalation calculator for E. coli strain JM109 (DE3) grown in LB media SE Clough, D Osman, TR Young, NJ Robinson bioRxiv, 2022.09. 02.506343, 2022 | | 2022 |
Molecular Characterisation of the Amyloid Precursor Protein TR Young | | 2017 |
Conference Theme: Molecular Imaging-Multiple Modalities Z Xiao, TR Young, AG Wedd | | |