The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C–Cdh1 A Herrero-Mendez, A Almeida, E Fernández, C Maestre, S Moncada, ... Nature cell biology 11 (6), 747-752, 2009 | 871 | 2009 |
Nitric oxide‐mediated mitochondrial damage in the brain: mechanisms and implications for neurodegenerative diseases JP Bolaños, A Almeida, V Stewart, S Peuchen, JM Land, JB Clark, ... Journal of neurochemistry 68 (6), 2227-2240, 1997 | 698 | 1997 |
Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway A Almeida, S Moncada, JP Bolaños Nature cell biology 6 (1), 45-51, 2004 | 542 | 2004 |
Different responses of astrocytes and neurons to nitric oxide: the role of glycolytically generated ATP in astrocyte protection A Almeida, J Almeida, JP Bolaños, S Moncada Proceedings of the National Academy of Sciences 98 (26), 15294-15299, 2001 | 491 | 2001 |
Roles of nitric oxide in brain hypoxia-ischemia JP Bolaños, A Almeida Biochimica et Biophysica Acta (BBA)-Bioenergetics 1411 (2-3), 415-436, 1999 | 474 | 1999 |
Glycolysis: a bioenergetic or a survival pathway? JP Bolaños, A Almeida, S Moncada Trends in biochemical sciences 35 (3), 145-149, 2010 | 387 | 2010 |
Complex I assembly into supercomplexes determines differential mitochondrial ROS production in neurons and astrocytes I Lopez-Fabuel, J Le Douce, A Logan, AM James, G Bonvento, ... Proceedings of the National Academy of Sciences 113 (46), 13063-13068, 2016 | 372 | 2016 |
Antioxidant and bioenergetic coupling between neurons and astrocytes S Fernandez-Fernandez, A Almeida, JP Bolaños Biochemical Journal 443 (1), 3-11, 2012 | 303 | 2012 |
Mitochondrial respiratory chain and free radical generation in stroke MA Moro, A Almeida, JP Bolaños, I Lizasoain Free Radical Biology and Medicine 39 (10), 1291-1304, 2005 | 303 | 2005 |
Oxygen and glucose deprivation induces mitochondrial dysfunction and oxidative stress in neurones but not in astrocytes in primary culture A Almeida, M Delgado‐Esteban, JP Bolaños, JM Medina Journal of neurochemistry 81 (2), 207-217, 2002 | 283 | 2002 |
Neuroprotective role of antidiabetic drug metformin against apoptotic cell death in primary cortical neurons MY El-Mir, D Detaille, G R-Villanueva, M Delgado-Esteban, B Guigas, ... Journal of Molecular Neuroscience 34, 77-87, 2008 | 282 | 2008 |
Glucose metabolism links astroglial mitochondria to cannabinoid effects D Jimenez-Blasco, A Busquets-Garcia, E Hebert-Chatelain, R Serrat, ... Nature 583 (7817), 603-608, 2020 | 204 | 2020 |
Interrelationships between astrocyte function, oxidative stress and antioxidant status within the central nervous system S Peuchen, JP Bolaños, SJR Heales, A Almeida, MR Duchen, JB Clark Progress in neurobiology 52 (4), 261-281, 1997 | 204 | 1997 |
Peroxisome proliferator-activated receptor γ thiazolidinedione agonists increase glucose metabolism in astrocytes CD Russo, V Gavrilyuk, G Weinberg, A Almeida, JP Bolanos, J Palmer, ... Journal of Biological Chemistry 278 (8), 5828-5836, 2003 | 203 | 2003 |
E3 ubiquitin ligase APC/C-Cdh1 accounts for the Warburg effect by linking glycolysis to cell proliferation A Almeida, JP Bolaños, S Moncada Proceedings of the National Academy of Sciences 107 (2), 738-741, 2010 | 200 | 2010 |
A transient inhibition of mitochondrial ATP synthesis by nitric oxide synthase activation triggered apoptosis in primary cortical neurons A Almeida, JP Bolaños Journal of neurochemistry 77 (2), 676-690, 2001 | 199 | 2001 |
Cdh1/Hct1-APC is essential for the survival of postmitotic neurons A Almeida, JP Bolanos, S Moreno Journal of Neuroscience 25 (36), 8115-8121, 2005 | 192 | 2005 |
Glutamate neurotoxicity is associated with nitric oxide-mediated mitochondrial dysfunction and glutathione depletion A Almeida, SJR Heales, JP Bolaños, JM Medina Brain research 790 (1-2), 209-216, 1998 | 182 | 1998 |
Peroxynitrite protects neurons against nitric oxide-mediated apoptosis: a key role for glucose-6-phosphate dehydrogenase activity in neuroprotection P Garcı́a-Nogales, A Almeida, JP Bolanos Journal of Biological Chemistry 278 (2), 864-874, 2003 | 179 | 2003 |
Astrocyte NMDA receptors' activity sustains neuronal survival through a Cdk5–Nrf2 pathway D Jimenez-Blasco, P Santofimia-Castaño, A Gonzalez, A Almeida, ... Cell Death & Differentiation 22 (11), 1877-1889, 2015 | 173 | 2015 |